quinethazone-3875 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the quinethazone-3875 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM22 ADAM metallopeptidase domain 22
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ANGPT4 angiopoietin 4
ATM ATM serine/threonine kinase
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BIN1 bridging integrator 1
C10ORF12 chromosome 10 open reading frame 12
C19ORF66 chromosome 19 open reading frame 66
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCL13 chemokine (C-C motif) ligand 13
CDH18 cadherin 18, type 2
CDK19 cyclin-dependent kinase 19
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLDN11 claudin 11
CLIC5 chloride intracellular channel 5
CNTFR ciliary neurotrophic factor receptor
CNTNAP1 contactin associated protein 1
CSRNP3 cysteine-serine-rich nuclear protein 3
CST2 cystatin SA
DMXL2 Dmx-like 2
DRD2 dopamine receptor D2
EMC3 ER membrane protein complex subunit 3
FGF16 fibroblast growth factor 16
FGL2 fibrinogen-like 2
FLCN folliculin
GPR137 G protein-coupled receptor 137
GPR68 G protein-coupled receptor 68
HAB1 B1 for mucin
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HEMK1 HemK methyltransferase family member 1
HIST1H1D histone cluster 1, H1d
HLF hepatic leukemia factor
HOXA6 homeobox A6
HRG histidine-rich glycoprotein
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFT140 intraflagellar transport 140
IGLJ3 immunoglobulin lambda joining 3
IL2 interleukin 2
IRF4 interferon regulatory factor 4
IVL involucrin
KCNIP1 Kv channel interacting protein 1
KDM4B lysine (K)-specific demethylase 4B
KIAA1024 KIAA1024
KIAA1456 KIAA1456
KLF12 Kruppel-like factor 12
LINC00260 long intergenic non-protein coding RNA 260
LTBP4 latent transforming growth factor beta binding protein 4
LY86 lymphocyte antigen 86
MAPK11 mitogen-activated protein kinase 11
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MON2 MON2 homolog (S. cerevisiae)
MSL3 male-specific lethal 3 homolog (Drosophila)
NF1 neurofibromin 1
NFIB nuclear factor I/B
NSUN6 NOP2/Sun domain family, member 6
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PARVB parvin, beta
PDE12 phosphodiesterase 12
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PHF20 PHD finger protein 20
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLIN2 perilipin 2
PLTP phospholipid transfer protein
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCE protein kinase C, epsilon
PRX periaxin
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS10 regulator of G-protein signaling 10
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPLP2 ribosomal protein, large, P2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SH3GL3 SH3-domain GRB2-like 3
SKIL SKI-like proto-oncogene
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMAD5 SMAD family member 5
SOGA1 suppressor of glucose, autophagy associated 1
SOX2 SRY (sex determining region Y)-box 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR3 small proline-rich protein 3
SSPN sarcospan
TBC1D29 TBC1 domain family, member 29
TDRD12 tudor domain containing 12
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNIK TRAF2 and NCK interacting kinase
TP53I11 tumor protein p53 inducible protein 11
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UHRF1BP1L UHRF1 binding protein 1-like
VN1R1 vomeronasal 1 receptor 1
WASL Wiskott-Aldrich syndrome-like
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACP2 acid phosphatase 2, lysosomal
ADTRP androgen-dependent TFPI-regulating protein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARHGAP4 Rho GTPase activating protein 4
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
ARSB arylsulfatase B
ATP7B ATPase, Cu++ transporting, beta polypeptide
BST2 bone marrow stromal cell antigen 2
C3 complement component 3
CAPN5 calpain 5
CCNK cyclin K
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD8A CD8a molecule
CDK6 cyclin-dependent kinase 6
CHRM3 cholinergic receptor, muscarinic 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
CXADR coxsackie virus and adenovirus receptor
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
DUSP9 dual specificity phosphatase 9
EGFL7 EGF-like-domain, multiple 7
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FAM120C family with sequence similarity 120C
FAM46C family with sequence similarity 46, member C
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FER fer (fps/fes related) tyrosine kinase
FKBP10 FK506 binding protein 10, 65 kDa
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GAMT guanidinoacetate N-methyltransferase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2BO histone cluster 1, H2bo
HIST1H3E histone cluster 1, H3e
IL17RA interleukin 17 receptor A
IQSEC2 IQ motif and Sec7 domain 2
ITM2C integral membrane protein 2C
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA1107 KIAA1107
LARP6 La ribonucleoprotein domain family, member 6
LIF leukemia inhibitory factor
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MALL mal, T-cell differentiation protein-like
MAP2 microtubule-associated protein 2
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MMP17 matrix metallopeptidase 17 (membrane-inserted)
NPM3 nucleophosmin/nucleoplasmin 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PCDHB13 protocadherin beta 13
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMEL premelanosome protein
PODNL1 podocan-like 1
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
QPCT glutaminyl-peptide cyclotransferase
RAB3A RAB3A, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RAI2 retinoic acid induced 2
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RIN1 Ras and Rab interactor 1
RNF121 ring finger protein 121
RNF2 ring finger protein 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNTA1 syntrophin, alpha 1
SOAT2 sterol O-acyltransferase 2
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TESC tescalcin
TEX40 testis expressed 40
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
WNT16 wingless-type MMTV integration site family, member 16
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZIC3 Zic family member 3
ZNF212 zinc finger protein 212
ZNF34 zinc finger protein 34
ZNF747 zinc finger protein 747