| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the quinethazone-3875 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ANGPT4 | angiopoietin 4 |
| ATM | ATM serine/threonine kinase |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BIN1 | bridging integrator 1 |
| C10ORF12 | chromosome 10 open reading frame 12 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CDH18 | cadherin 18, type 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| CLDN11 | claudin 11 |
| CLIC5 | chloride intracellular channel 5 |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTNAP1 | contactin associated protein 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CST2 | cystatin SA |
| DMXL2 | Dmx-like 2 |
| DRD2 | dopamine receptor D2 |
| EMC3 | ER membrane protein complex subunit 3 |
| FGF16 | fibroblast growth factor 16 |
| FGL2 | fibrinogen-like 2 |
| FLCN | folliculin |
| GPR137 | G protein-coupled receptor 137 |
| GPR68 | G protein-coupled receptor 68 |
| HAB1 | B1 for mucin |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIST1H1D | histone cluster 1, H1d |
| HLF | hepatic leukemia factor |
| HOXA6 | homeobox A6 |
| HRG | histidine-rich glycoprotein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFT140 | intraflagellar transport 140 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL2 | interleukin 2 |
| IRF4 | interferon regulatory factor 4 |
| IVL | involucrin |
| KCNIP1 | Kv channel interacting protein 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA1024 | KIAA1024 |
| KIAA1456 | KIAA1456 |
| KLF12 | Kruppel-like factor 12 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY86 | lymphocyte antigen 86 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NF1 | neurofibromin 1 |
| NFIB | nuclear factor I/B |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PARVB | parvin, beta |
| PDE12 | phosphodiesterase 12 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PHF20 | PHD finger protein 20 |
| PLCH1 | phospholipase C, eta 1 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLIN2 | perilipin 2 |
| PLTP | phospholipid transfer protein |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PRKCE | protein kinase C, epsilon |
| PRX | periaxin |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPLP2 | ribosomal protein, large, P2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SKIL | SKI-like proto-oncogene |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SMAD5 | SMAD family member 5 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRR3 | small proline-rich protein 3 |
| SSPN | sarcospan |
| TBC1D29 | TBC1 domain family, member 29 |
| TDRD12 | tudor domain containing 12 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNIK | TRAF2 and NCK interacting kinase |
| TP53I11 | tumor protein p53 inducible protein 11 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| VN1R1 | vomeronasal 1 receptor 1 |
| WASL | Wiskott-Aldrich syndrome-like |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACP2 | acid phosphatase 2, lysosomal |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARMC4 | armadillo repeat containing 4 |
| ARRB1 | arrestin, beta 1 |
| ARSB | arylsulfatase B |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BST2 | bone marrow stromal cell antigen 2 |
| C3 | complement component 3 |
| CAPN5 | calpain 5 |
| CCNK | cyclin K |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD8A | CD8a molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLGN | calmegin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CXADR | coxsackie virus and adenovirus receptor |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP9 | dual specificity phosphatase 9 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| FAM120C | family with sequence similarity 120C |
| FAM46C | family with sequence similarity 46, member C |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FER | fer (fps/fes related) tyrosine kinase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH2L | G patch domain containing 2-like |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3E | histone cluster 1, H3e |
| IL17RA | interleukin 17 receptor A |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITM2C | integral membrane protein 2C |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIAA1107 | KIAA1107 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LIF | leukemia inhibitory factor |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MALL | mal, T-cell differentiation protein-like |
| MAP2 | microtubule-associated protein 2 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PADI1 | peptidyl arginine deiminase, type I |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDHB13 | protocadherin beta 13 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLCD1 | phospholipase C, delta 1 |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMEL | premelanosome protein |
| PODNL1 | podocan-like 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRAMEF11 | PRAME family member 11 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB3A | RAB3A, member RAS oncogene family |
| RAB5C | RAB5C, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RETSAT | retinol saturase (all-trans-retinol 13,14-reductase) |
| RIN1 | Ras and Rab interactor 1 |
| RNF121 | ring finger protein 121 |
| RNF2 | ring finger protein 2 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNTA1 | syntrophin, alpha 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TESC | tescalcin |
| TEX40 | testis expressed 40 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFF2 | trefoil factor 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP37 | ZFP37 zinc finger protein |
| ZIC3 | Zic family member 3 |
| ZNF212 | zinc finger protein 212 |
| ZNF34 | zinc finger protein 34 |
| ZNF747 | zinc finger protein 747 |