quinethazone-4351 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the quinethazone-4351 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDOB aldolase B, fructose-bisphosphate
APC2 adenomatosis polyposis coli 2
ATXN7L1 ataxin 7-like 1
AVPR1B arginine vasopressin receptor 1B
BTN3A1 butyrophilin, subfamily 3, member A1
C3 complement component 3
CAPN2 calpain 2, (m/II) large subunit
CC2D1A coiled-coil and C2 domain containing 1A
CCKAR cholecystokinin A receptor
CD160 CD160 molecule
CD300C CD300c molecule
CDC25C cell division cycle 25C
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CNTN1 contactin 1
CNTNAP2 contactin associated protein-like 2
COL6A2 collagen, type VI, alpha 2
CPB1 carboxypeptidase B1 (tissue)
CROCC ciliary rootlet coiled-coil, rootletin
CTIF CBP80/20-dependent translation initiation factor
CTRL chymotrypsin-like
DGCR8 DGCR8 microprocessor complex subunit
DPF1 D4, zinc and double PHD fingers family 1
DSC3 desmocollin 3
EN2 engrailed homeobox 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERN2 endoplasmic reticulum to nucleus signaling 2
FCMR Fc fragment of IgM receptor
FGF16 fibroblast growth factor 16
FRMD1 FERM domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
G0S2 G0/G1 switch 2
GHRHR growth hormone releasing hormone receptor
GLP1R glucagon-like peptide 1 receptor
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GPER1 G protein-coupled estrogen receptor 1
GRM7 glutamate receptor, metabotropic 7
HIST1H3J histone cluster 1, H3j
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNMT histamine N-methyltransferase
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAM3 junctional adhesion molecule 3
KHSRP KH-type splicing regulatory protein
KLRD1 killer cell lectin-like receptor subfamily D, member 1
LINC00260 long intergenic non-protein coding RNA 260
LMO1 LIM domain only 1 (rhombotin 1)
MAN1C1 mannosidase, alpha, class 1C, member 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MBP myelin basic protein
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MKRN3 makorin ring finger protein 3
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MORC1 MORC family CW-type zinc finger 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MST1 macrophage stimulating 1
MUC3B mucin 3B, cell surface associated
MX1 MX dynamin-like GTPase 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NR4A1 nuclear receptor subfamily 4, group A, member 1
PDE4C phosphodiesterase 4C, cAMP-specific
PEG10 paternally expressed 10
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLD2 phospholipase D2
PXDC1 PX domain containing 1
RAB6B RAB6B, member RAS oncogene family
REM1 RAS (RAD and GEM)-like GTP-binding 1
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEZ6L seizure related 6 homolog (mouse)-like
SH2D3A SH2 domain containing 3A
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
TAGLN3 transgelin 3
TBX3 T-box 3
TBX5 T-box 5
TBX6 T-box 6
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TP53I11 tumor protein p53 inducible protein 11
TPMT thiopurine S-methyltransferase
TRIM31 tripartite motif containing 31
TRIM36 tripartite motif containing 36
TRIO trio Rho guanine nucleotide exchange factor
TSC2 tuberous sclerosis 2
TSC22D2 TSC22 domain family, member 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ARMC4 armadillo repeat containing 4
ARRB1 arrestin, beta 1
BIRC7 baculoviral IAP repeat containing 7
C11ORF21 chromosome 11 open reading frame 21
C11ORF63 chromosome 11 open reading frame 63
CA4 carbonic anhydrase IV
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX2 chromobox homolog 2
CCDC25 coiled-coil domain containing 25
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CGA glycoprotein hormones, alpha polypeptide
CHML choroideremia-like (Rab escort protein 2)
CLCN6 chloride channel, voltage-sensitive 6
CRIP1 cysteine-rich protein 1 (intestinal)
CRLF1 cytokine receptor-like factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DEPDC5 DEP domain containing 5
DNASE1L2 deoxyribonuclease I-like 2
DPY19L1P1 DPY19L1 pseudogene 1
EGFL7 EGF-like-domain, multiple 7
ELP6 elongator acetyltransferase complex subunit 6
ELSPBP1 epididymal sperm binding protein 1
EPHX2 epoxide hydrolase 2, cytoplasmic
EPPK1 epiplakin 1
FAAH fatty acid amide hydrolase
FGF23 fibroblast growth factor 23
FLJ22184
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXB2 homeobox B2
IFI27 interferon, alpha-inducible protein 27
IGSF6 immunoglobulin superfamily, member 6
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT83 keratin 83, type II
LINS lines homolog (Drosophila)
LOC157562 uncharacterized LOC157562
LONRF3 LON peptidase N-terminal domain and ring finger 3
LTBP2 latent transforming growth factor beta binding protein 2
MAGEF1 melanoma antigen family F1
MALL mal, T-cell differentiation protein-like
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MGC12488
MXD3 MAX dimerization protein 3
MYO1F myosin IF
NACA2 nascent polypeptide-associated complex alpha subunit 2
OSMR oncostatin M receptor
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARP3 poly (ADP-ribose) polymerase family, member 3
PDE12 phosphodiesterase 12
PITX2 paired-like homeodomain 2
PLAC1 placenta-specific 1
POLH polymerase (DNA directed), eta
PPT2 palmitoyl-protein thioesterase 2
PRF1 perforin 1 (pore forming protein)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTCD2 pentatricopeptide repeat domain 2
RAB30 RAB30, member RAS oncogene family
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
S100A7 S100 calcium binding protein A7
SCGB2A2 secretoglobin, family 2A, member 2
SEC14L2 SEC14-like 2 (S. cerevisiae)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLPI secretory leukocyte peptidase inhibitor
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
STX1A syntaxin 1A (brain)
TBX19 T-box 19
TDRD1 tudor domain containing 1
TEX40 testis expressed 40
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TM4SF5 transmembrane 4 L six family member 5
TMEM53 transmembrane protein 53
TPSG1 tryptase gamma 1
USP27X ubiquitin specific peptidase 27, X-linked
VEZT vezatin, adherens junctions transmembrane protein
VGF VGF nerve growth factor inducible
ZNF134 zinc finger protein 134
ZNF204P zinc finger protein 204, pseudogene
ZNF205 zinc finger protein 205
ZNF304 zinc finger protein 304
ZNF34 zinc finger protein 34
ZNF37BP zinc finger protein 37B, pseudogene
ZNF41 zinc finger protein 41
ZNF480 zinc finger protein 480
ZNF532 zinc finger protein 532