quinethazone-4529 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the quinethazone-4529 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADCK2 aarF domain containing kinase 2
AFF3 AF4/FMR2 family, member 3
AFF4 AF4/FMR2 family, member 4
AKT2 v-akt murine thymoma viral oncogene homolog 2
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASCL1 achaete-scute family bHLH transcription factor 1
ATXN2L ataxin 2-like
BEX1 brain expressed, X-linked 1
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CADM4 cell adhesion molecule 4
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHI3L2 chitinase 3-like 2
CNGA1 cyclic nucleotide gated channel alpha 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DCLK2 doublecortin-like kinase 2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DOPEY2 dopey family member 2
EDA ectodysplasin A
ELAC2 elaC ribonuclease Z 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FBXO22 F-box protein 22
FGF5 fibroblast growth factor 5
FGFR1 fibroblast growth factor receptor 1
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
FPR1 formyl peptide receptor 1
FYB FYN binding protein
GAS7 growth arrest-specific 7
GATA3 GATA binding protein 3
GK glycerol kinase
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AB histone cluster 1, H2ab
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUND jun D proto-oncogene
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KCTD13 potassium channel tetramerization domain containing 13
KIAA1024 KIAA1024
KIF5C kinesin family member 5C
LRP1 low density lipoprotein receptor-related protein 1
MDFI MyoD family inhibitor
MEGF9 multiple EGF-like-domains 9
MON2 MON2 homolog (S. cerevisiae)
MRPL41 mitochondrial ribosomal protein L41
MUC4 mucin 4, cell surface associated
MVB12B multivesicular body subunit 12B
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow
NCOR2 nuclear receptor corepressor 2
NFX1 nuclear transcription factor, X-box binding 1
NOL4 nucleolar protein 4
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NTF3 neurotrophin 3
ORC5 origin recognition complex, subunit 5
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDE11A phosphodiesterase 11A
PDGFA platelet-derived growth factor alpha polypeptide
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PECAM1 platelet/endothelial cell adhesion molecule 1
PILRA paired immunoglobin-like type 2 receptor alpha
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRUNE2 prune homolog 2 (Drosophila)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RFPL3S RFPL3 antisense
RHEB Ras homolog enriched in brain
RUNX1 runt-related transcription factor 1
SCN3A sodium channel, voltage gated, type III alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SORBS2 sorbin and SH3 domain containing 2
SOS2 son of sevenless homolog 2 (Drosophila)
SPRR2B small proline-rich protein 2B
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D2B TBC1 domain family, member 2B
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THPO thrombopoietin
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK2 tyrosine kinase, non-receptor, 2
UBE2B ubiquitin-conjugating enzyme E2B
WT1 Wilms tumor 1
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF287 zinc finger protein 287
ZNF573 zinc finger protein 573
ZSCAN18 zinc finger and SCAN domain containing 18
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
AGMAT agmatine ureohydrolase (agmatinase)
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P1 annexin A2 pseudogene 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATXN2 ataxin 2
AXIN1 axin 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
C11ORF30 chromosome 11 open reading frame 30
C5ORF42 chromosome 5 open reading frame 42
C5ORF45 chromosome 5 open reading frame 45
CBX4 chromobox homolog 4
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDH7 cadherin 7, type 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLIC3 chloride intracellular channel 3
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNN2 calponin 2
CNTLN centlein, centrosomal protein
CYBRD1 cytochrome b reductase 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELP6 elongator acetyltransferase complex subunit 6
FBRS fibrosin
FBXW12 F-box and WD repeat domain containing 12
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GMIP GEM interacting protein
GRTP1 growth hormone regulated TBC protein 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HIRA histone cell cycle regulator
HIST1H2AK histone cluster 1, H2ak
HIST1H3G histone cluster 1, H3g
HOXA6 homeobox A6
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HYAL3 hyaluronoglucosaminidase 3
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDM5C lysine (K)-specific demethylase 5C
KLF3 Kruppel-like factor 3 (basic)
LOC390998 ribosomal protein L10 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LZTR1 leucine-zipper-like transcription regulator 1
MBTD1 mbt domain containing 1
MON1B MON1 secretory trafficking family member B
MT1HL1 metallothionein 1H-like 1
MTHFSD methenyltetrahydrofolate synthetase domain containing
MYO1F myosin IF
NKX3-2 NK3 homeobox 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPFFR1 neuropeptide FF receptor 1
PDE12 phosphodiesterase 12
PHKG2 phosphorylase kinase, gamma 2 (testis)
PLAC1 placenta-specific 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRR7 proline rich 7 (synaptic)
PTPRS protein tyrosine phosphatase, receptor type, S
RBM38 RNA binding motif protein 38
RGCC regulator of cell cycle
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPS17P5 ribosomal protein S17 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SDC3 syndecan 3
SETBP1 SET binding protein 1
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SMR3A submaxillary gland androgen regulated protein 3A
STARD5 StAR-related lipid transfer (START) domain containing 5
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
THOC6 THO complex 6
TMEM19 transmembrane protein 19
TNRC6B trinucleotide repeat containing 6B
TUBG2 tubulin, gamma 2
ULBP2 UL16 binding protein 2
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
VEGFB vascular endothelial growth factor B
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB39 zinc finger and BTB domain containing 39
ZFAND3 zinc finger, AN1-type domain 3
ZNF205 zinc finger protein 205
ZNF446 zinc finger protein 446
ZNF510 zinc finger protein 510