quinidine-3191 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the quinidine-3191 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACAN aggrecan
ADAM19 ADAM metallopeptidase domain 19
ALPL alkaline phosphatase, liver/bone/kidney
ANPEP alanyl (membrane) aminopeptidase
AQP5 aquaporin 5
ARL3 ADP-ribosylation factor-like 3
ATXN8OS ATXN8 opposite strand (non-protein coding)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BIN1 bridging integrator 1
C21ORF2 chromosome 21 open reading frame 2
CALD1 caldesmon 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC70 coiled-coil domain containing 70
CCDC85B coiled-coil domain containing 85B
CD2 CD2 molecule
CD6 CD6 molecule
CDRT1 CMT1A duplicated region transcript 1
CHIA chitinase, acidic
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
COL4A6 collagen, type IV, alpha 6
CPB1 carboxypeptidase B1 (tissue)
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
CYTH4 cytohesin 4
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGKB diacylglycerol kinase, beta 90kDa
DLX4 distal-less homeobox 4
DNAI2 dynein, axonemal, intermediate chain 2
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
ETV4 ets variant 4
FBLN1 fibulin 1
FYB FYN binding protein
GDNF glial cell derived neurotrophic factor
GGT1 gamma-glutamyltransferase 1
GLUD2 glutamate dehydrogenase 2
GPR162 G protein-coupled receptor 162
GPSM3 G-protein signaling modulator 3
GRPR gastrin-releasing peptide receptor
HAO2 hydroxyacid oxidase 2 (long chain)
HHLA2 HERV-H LTR-associating 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HYAL1 hyaluronoglucosaminidase 1
JAKMIP2 janus kinase and microtubule interacting protein 2
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA0040 KIAA0040
LMOD1 leiomodin 1 (smooth muscle)
MAGEA8 melanoma antigen family A8
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MINK1 misshapen-like kinase 1
MITF microphthalmia-associated transcription factor
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCAM1 neural cell adhesion molecule 1
NCKIPSD NCK interacting protein with SH3 domain
NPVF neuropeptide VF precursor
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PAPPA2 pappalysin 2
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PKN2 protein kinase N2
PLCL2 phospholipase C-like 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPARD peroxisome proliferator-activated receptor delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAB6B RAB6B, member RAS oncogene family
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGS14 regulator of G-protein signaling 14
RPL35A ribosomal protein L35a
SAG S-antigen; retina and pineal gland (arrestin)
SCG2 secretogranin II
SIM2 single-minded family bHLH transcription factor 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNTA1 syntrophin, alpha 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STOM stomatin
TAC1 tachykinin, precursor 1
TAS2R4 taste receptor, type 2, member 4
TAT tyrosine aminotransferase
TBX5 T-box 5
TFCP2L1 transcription factor CP2-like 1
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THY1 Thy-1 cell surface antigen
TMCC2 transmembrane and coiled-coil domain family 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM22 tripartite motif containing 22
TSC2 tuberous sclerosis 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
UTS2 urotensin 2
VGLL3 vestigial-like family member 3
WIF1 WNT inhibitory factor 1
ZNF175 zinc finger protein 175
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACSF2 acyl-CoA synthetase family member 2
ADCY6 adenylate cyclase 6
ADM adrenomedullin
ALAS1 5'-aminolevulinate synthase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
BAG4 BCL2-associated athanogene 4
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C8ORF60 chromosome 8 open reading frame 60
CADPS2 Ca++-dependent secretion activator 2
CCDC132 coiled-coil domain containing 132
CD302 CD302 molecule
CGREF1 cell growth regulator with EF-hand domain 1
CHRM3 cholinergic receptor, muscarinic 3
CIR1 corepressor interacting with RBPJ, 1
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDAR ectodysplasin A receptor
F8 coagulation factor VIII, procoagulant component
FAM131A family with sequence similarity 131, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FPGS folylpolyglutamate synthase
FRS2 fibroblast growth factor receptor substrate 2
GBP2 guanylate binding protein 2, interferon-inducible
GPATCH3 G patch domain containing 3
GTPBP2 GTP binding protein 2
HIRA histone cell cycle regulator
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFT22 intraflagellar transport 22
INCENP inner centromere protein antigens 135/155kDa
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
JOSD1 Josephin domain containing 1
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCTD7 potassium channel tetramerization domain containing 7
KIF13A kinesin family member 13A
KLHL26 kelch-like family member 26
LHX1 LIM homeobox 1
LOC390998 ribosomal protein L10 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LYRM9 LYR motif containing 9
LYZ lysozyme
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAMLD1 mastermind-like domain containing 1
MBTD1 mbt domain containing 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN3 mucolipin 3
MDM4 MDM4, p53 regulator
MED9 mediator complex subunit 9
MPO myeloperoxidase
MTERF4 mitochondrial transcription termination factor 4
MYBBP1A MYB binding protein (P160) 1a
MYL5 myosin, light chain 5, regulatory
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACS1 phosphofurin acidic cluster sorting protein 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PITX2 paired-like homeodomain 2
PLA2G15 phospholipase A2, group XV
PLXNA3 plexin A3
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRR4 proline rich 4 (lacrimal)
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTPRE protein tyrosine phosphatase, receptor type, E
PYCRL pyrroline-5-carboxylate reductase-like
QSER1 glutamine and serine rich 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPGR retinitis pigmentosa GTPase regulator
SCAMP5 secretory carrier membrane protein 5
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D4A SH2 domain containing 4A
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SRGN serglycin
STK16 serine/threonine kinase 16
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTA T-cell leukemia translocation altered
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFRC transferrin receptor
THRAP3 thyroid hormone receptor associated protein 3
TMPRSS3 transmembrane protease, serine 3
TNRC6B trinucleotide repeat containing 6B
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3C tubulin, alpha 3c
ZBTB6 zinc finger and BTB domain containing 6
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF35 zinc finger protein 35
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZNF74 zinc finger protein 74