quinidine-5793 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the quinidine-5793 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP11 A kinase (PRKA) anchor protein 11
AKAP5 A kinase (PRKA) anchor protein 5
ALPK1 alpha-kinase 1
ASIC1 acid sensing (proton gated) ion channel 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP9A ATPase, class II, type 9A
BMP7 bone morphogenetic protein 7
C1ORF95 chromosome 1 open reading frame 95
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD58 CD58 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDC14A cell division cycle 14A
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLDN17 claudin 17
CLUL1 clusterin-like 1 (retinal)
COL7A1 collagen, type VII, alpha 1
DDO D-aspartate oxidase
DMBT1 deleted in malignant brain tumors 1
DST dystonin
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FBXL8 F-box and leucine-rich repeat protein 8
FBXO2 F-box protein 2
FGD2 FYVE, RhoGEF and PH domain containing 2
FSCN3 fascin actin-bundling protein 3, testicular
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GJA4 gap junction protein, alpha 4, 37kDa
GJA8 gap junction protein, alpha 8, 50kDa
GK glycerol kinase
HHIPL2 HHIP-like 2
HLA-DOA major histocompatibility complex, class II, DO alpha
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMG20B high mobility group 20B
HMOX1 heme oxygenase 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ICMT isoprenylcysteine carboxyl methyltransferase
ICOSLG inducible T-cell co-stimulator ligand
IFT27 intraflagellar transport 27
IRF4 interferon regulatory factor 4
JAK3 Janus kinase 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIF13A kinesin family member 13A
KMT2A lysine (K)-specific methyltransferase 2A
KRTAP1-3 keratin associated protein 1-3
LOC100294391 uncharacterized LOC100294391
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
OR2W1 olfactory receptor, family 2, subfamily W, member 1
PAPPA2 pappalysin 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDHB1 protocadherin beta 1
PDE10A phosphodiesterase 10A
PKD1 polycystic kidney disease 1 (autosomal dominant)
PPARD peroxisome proliferator-activated receptor delta
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVR poliovirus receptor
PWAR5 Prader Willi/Angelman region RNA 5
RAB27B RAB27B, member RAS oncogene family
RBPMS RNA binding protein with multiple splicing
RECQL5 RecQ protein-like 5
ROM1 retinal outer segment membrane protein 1
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
S100A13 S100 calcium binding protein A13
S1PR1 sphingosine-1-phosphate receptor 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SEZ6L seizure related 6 homolog (mouse)-like
SH2B1 SH2B adaptor protein 1
SH3BP1 SH3-domain binding protein 1
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
ST18 suppression of tumorigenicity 18, zinc finger
STAB1 stabilin 1
SULF1 sulfatase 1
TFR2 transferrin receptor 2
TRAC T cell receptor alpha constant
TRIM22 tripartite motif containing 22
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSC22D3 TSC22 domain family, member 3
TTLL5 tubulin tyrosine ligase-like family member 5
TUBA3C tubulin, alpha 3c
WDR25 WD repeat domain 25
ZNF224 zinc finger protein 224
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACSL4 acyl-CoA synthetase long-chain family member 4
ADTRP androgen-dependent TFPI-regulating protein
AGO4 argonaute RISC catalytic component 4
ALAS1 5'-aminolevulinate synthase 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGAP10 Rho GTPase activating protein 10
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATAT1 alpha tubulin acetyltransferase 1
AXIN1 axin 1
BEND5 BEN domain containing 5
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C17ORF53 chromosome 17 open reading frame 53
C1R complement component 1, r subcomponent
CA11 carbonic anhydrase XI
CARM1 coactivator-associated arginine methyltransferase 1
CCDC71 coiled-coil domain containing 71
CCNO cyclin O
CEMIP cell migration inducing protein, hyaluronan binding
CISH cytokine inducible SH2-containing protein
CLEC16A C-type lectin domain family 16, member A
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORO2A coronin, actin binding protein, 2A
CUL9 cullin 9
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DBF4B DBF4 zinc finger B
DDIT4 DNA-damage-inducible transcript 4
ECM1 extracellular matrix protein 1
EGR2 early growth response 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FBXL7 F-box and leucine-rich repeat protein 7
FKBP10 FK506 binding protein 10, 65 kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FRS3 fibroblast growth factor receptor substrate 3
GALE UDP-galactose-4-epimerase
GAN gigaxonin
GMEB1 glucocorticoid modulatory element binding protein 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H3C histone cluster 1, H3c
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL2 interleukin 2
INF2 inverted formin, FH2 and WH2 domain containing
JAM3 junctional adhesion molecule 3
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA1549L KIAA1549-like
KIRREL kin of IRRE like (Drosophila)
KRT86 keratin 86, type II
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC100286895 cell division cycle 27 homolog pseudogene
LOC257152 uncharacterized LOC257152
MAGEH1 melanoma antigen family H1
MANBA mannosidase, beta A, lysosomal
MATN3 matrilin 3
MMRN2 multimerin 2
MNX1 motor neuron and pancreas homeobox 1
MOXD1 monooxygenase, DBH-like 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYO1F myosin IF
NDRG1 N-myc downstream regulated 1
NHEJ1 nonhomologous end-joining factor 1
NT5M 5',3'-nucleotidase, mitochondrial
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHEX phosphate regulating endopeptidase homolog, X-linked
PLAT plasminogen activator, tissue
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS16 protease, serine, 16 (thymus)
PTDSS2 phosphatidylserine synthase 2
RHOBTB2 Rho-related BTB domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
SETBP1 SET binding protein 1
SH2D2A SH2 domain containing 2A
TBC1D19 TBC1 domain family, member 19
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEP1 telomerase-associated protein 1
TFRC transferrin receptor
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM8B transmembrane protein 8B
TRAF2 TNF receptor-associated factor 2
TRIM21 tripartite motif containing 21
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UNC119 unc-119 homolog (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
USP27X ubiquitin specific peptidase 27, X-linked
WDR33 WD repeat domain 33
WNT7A wingless-type MMTV integration site family, member 7A
YPEL1 yippee-like 1 (Drosophila)
ZFHX3 zinc finger homeobox 3
ZNF204P zinc finger protein 204, pseudogene
ZNF510 zinc finger protein 510
ZNF76 zinc finger protein 76
ZNF778 zinc finger protein 778
ZNF862 zinc finger protein 862