quinisocaine-2151 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the quinisocaine-2151 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACACB acetyl-CoA carboxylase beta
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALAD aminolevulinate dehydratase
ANO2 anoctamin 2, calcium activated chloride channel
APAF1 apoptotic peptidase activating factor 1
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
ATXN3 ataxin 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC57 coiled-coil domain containing 57
CCDC71 coiled-coil domain containing 71
CD209 CD209 molecule
CLCN4 chloride channel, voltage-sensitive 4
COL4A2 collagen, type IV, alpha 2
CPTP ceramide-1-phosphate transfer protein
CXCL6 chemokine (C-X-C motif) ligand 6
CXCR3 chemokine (C-X-C motif) receptor 3
DLK2 delta-like 2 homolog (Drosophila)
EDIL3 EGF-like repeats and discoidin I-like domains 3
EDRF1 erythroid differentiation regulatory factor 1
EFNA5 ephrin-A5
EFNB2 ephrin-B2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FAM127B family with sequence similarity 127, member B
FAM155A family with sequence similarity 155, member A
FAM49B family with sequence similarity 49, member B
FAM65A family with sequence similarity 65, member A
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FOLR2 folate receptor 2 (fetal)
FOXD2 forkhead box D2
FRAS1 Fraser extracellular matrix complex subunit 1
FZD1 frizzled class receptor 1
GAB1 GRB2-associated binding protein 1
GALC galactosylceramidase
GPR153 G protein-coupled receptor 153
GRIA4 glutamate receptor, ionotropic, AMPA 4
HIST1H4E histone cluster 1, H4e
ICOS inducible T-cell co-stimulator
IFI6 interferon, alpha-inducible protein 6
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCK IQ motif containing K
ITGB5 integrin, beta 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2
MAP4 microtubule-associated protein 4
MAP7 microtubule-associated protein 7
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MORN1 MORN repeat containing 1
MR1 major histocompatibility complex, class I-related
MUC3B mucin 3B, cell surface associated
MYO15A myosin XVA
NCLN nicalin
NEK9 NIMA-related kinase 9
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NIN ninein (GSK3B interacting protein)
NPAT nuclear protein, ataxia-telangiectasia locus
NPEPL1 aminopeptidase-like 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PROL1 proline rich, lacrimal 1
PTCRA pre T-cell antigen receptor alpha
PYGB phosphorylase, glycogen; brain
PYHIN1 pyrin and HIN domain family, member 1
RAB40A RAB40A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
REPS2 RALBP1 associated Eps domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SAG S-antigen; retina and pineal gland (arrestin)
SERHL2 serine hydrolase-like 2
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SORBS3 sorbin and SH3 domain containing 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
TBL2 transducin (beta)-like 2
TCAF1 TRPM8 channel-associated factor 1
THSD7A thrombospondin, type I, domain containing 7A
TMC7 transmembrane channel-like 7
TMEM2 transmembrane protein 2
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
ZFPL1 zinc finger protein-like 1
ZNF510 zinc finger protein 510
ZNF518A zinc finger protein 518A
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ACAD10 acyl-CoA dehydrogenase family, member 10
AHCTF1 AT hook containing transcription factor 1
AHDC1 AT hook, DNA binding motif, containing 1
ANKRD36 ankyrin repeat domain 36
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARSB arylsulfatase B
ASB7 ankyrin repeat and SOCS box containing 7
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPN asporin
AXIN1 axin 1
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
BNC2 basonuclin 2
BPHL biphenyl hydrolase-like (serine hydrolase)
BTBD18 BTB (POZ) domain containing 18
C22ORF46 chromosome 22 open reading frame 46
C5AR1 complement component 5a receptor 1
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CD3D CD3d molecule, delta (CD3-TCR complex)
CD9 CD9 molecule
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLEC4E C-type lectin domain family 4, member E
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CSF1R colony stimulating factor 1 receptor
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEFB1 defensin, beta 1
DGKG diacylglycerol kinase, gamma 90kDa
DNM3 dynamin 3
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGR2 early growth response 2
ELP6 elongator acetyltransferase complex subunit 6
ERCC2 excision repair cross-complementation group 2
ETV4 ets variant 4
FAM188A family with sequence similarity 188, member A
FOSL1 FOS-like antigen 1
FURIN furin (paired basic amino acid cleaving enzyme)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GSTT1 glutathione S-transferase theta 1
HHLA3 HERV-H LTR-associating 3
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HRH1 histamine receptor H1
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
KDM5C lysine (K)-specific demethylase 5C
KIAA0754 KIAA0754
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAK male germ cell-associated kinase
MANSC1 MANSC domain containing 1
MAPK13 mitogen-activated protein kinase 13
MED15 mediator complex subunit 15
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MYOZ3 myozenin 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NTSR1 neurotensin receptor 1 (high affinity)
PADI1 peptidyl arginine deiminase, type I
PDGFD platelet derived growth factor D
PHACTR1 phosphatase and actin regulator 1
PLTP phospholipid transfer protein
PMFBP1 polyamine modulated factor 1 binding protein 1
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PPT2 palmitoyl-protein thioesterase 2
PRR7 proline rich 7 (synaptic)
RAB13 RAB13, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RRAS related RAS viral (r-ras) oncogene homolog
SETD6 SET domain containing 6
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI1 snail family zinc finger 1
STEAP3 STEAP family member 3, metalloreductase
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
THEM6 thioesterase superfamily member 6
TMEM180 transmembrane protein 180
TOR4A torsin family 4, member A
TRAIP TRAF interacting protein
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
WASF3 WAS protein family, member 3
ZFHX2 zinc finger homeobox 2
ZMYM3 zinc finger, MYM-type 3
ZNF250 zinc finger protein 250
ZNF528 zinc finger protein 528
ZNF770 zinc finger protein 770
ZNHIT2 zinc finger, HIT-type containing 2