quinisocaine-2807 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the quinisocaine-2807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATF3 activating transcription factor 3
ATXN7L1 ataxin 7-like 1
BAAT bile acid CoA:amino acid N-acyltransferase
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BIRC7 baculoviral IAP repeat containing 7
CABIN1 calcineurin binding protein 1
CARD14 caspase recruitment domain family, member 14
CCDC57 coiled-coil domain containing 57
CD160 CD160 molecule
CD48 CD48 molecule
CD82 CD82 molecule
CD83 CD83 molecule
CGA glycoprotein hormones, alpha polypeptide
CLTA clathrin, light chain A
CTSE cathepsin E
CXORF21 chromosome X open reading frame 21
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
DAZL deleted in azoospermia-like
DDIT3 DNA-damage-inducible transcript 3
DNASE1L3 deoxyribonuclease I-like 3
DNASE2B deoxyribonuclease II beta
DST dystonin
DUSP10 dual specificity phosphatase 10
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGR1 early growth response 1
ESR1 estrogen receptor 1
ETV5 ets variant 5
F13A1 coagulation factor XIII, A1 polypeptide
FLJ22184
FOSL1 FOS-like antigen 1
FST follistatin
GAB1 GRB2-associated binding protein 1
GLB1L galactosidase, beta 1-like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HBEGF heparin-binding EGF-like growth factor
HFE hemochromatosis
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HOXC4 homeobox C4
ICAM1 intercellular adhesion molecule 1
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD17 potassium channel tetramerization domain containing 17
LEPR leptin receptor
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBP2 latent transforming growth factor beta binding protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MED16 mediator complex subunit 16
MXD4 MAX dimerization protein 4
MYH14 myosin, heavy chain 14, non-muscle
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
N4BP2L1 NEDD4 binding protein 2-like 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPY2R neuropeptide Y receptor Y2
PACS1 phosphofurin acidic cluster sorting protein 1
PAX5 paired box 5
POU5F1B POU class 5 homeobox 1B
PRKCQ protein kinase C, theta
PTRF polymerase I and transcript release factor
RAB3B RAB3B, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPL37A ribosomal protein L37a
RSG1 REM2 and RAB-like small GTPase 1
SAPCD1 suppressor APC domain containing 1
SARDH sarcosine dehydrogenase
SLC43A3 solute carrier family 43, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SOX15 SRY (sex determining region Y)-box 15
SPTA1 spectrin, alpha, erythrocytic 1
ST7L suppression of tumorigenicity 7 like
STX2 syntaxin 2
TBCD tubulin folding cofactor D
TBX10 T-box 10
TCF25 transcription factor 25 (basic helix-loop-helix)
TENM1 teneurin transmembrane protein 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UCN urocortin
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VAC14 Vac14 homolog (S. cerevisiae)
WAS Wiskott-Aldrich syndrome
WDR62 WD repeat domain 62
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ASAP1-IT1 ASAP1 intronic transcript 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
BAG4 BCL2-associated athanogene 4
BCL7C B-cell CLL/lymphoma 7C
BCORL1 BCL6 corepressor-like 1
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C11ORF30 chromosome 11 open reading frame 30
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
CA2 carbonic anhydrase II
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC15 coiled-coil domain containing 15
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CECR5 cat eye syndrome chromosome region, candidate 5
CLSTN2 calsyntenin 2
COL4A5 collagen, type IV, alpha 5
CRY2 cryptochrome circadian clock 2
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DEAF1 DEAF1 transcription factor
DENND1B DENN/MADD domain containing 1B
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
EFHD2 EF-hand domain family, member D2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FAM127B family with sequence similarity 127, member B
FAM188A family with sequence similarity 188, member A
GAMT guanidinoacetate N-methyltransferase
GAN gigaxonin
GID4 GID complex subunit 4
GLS2 glutaminase 2 (liver, mitochondrial)
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2AI histone cluster 1, H2ai
IQCG IQ motif containing G
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCTD20 potassium channel tetramerization domain containing 20
KIAA0125 KIAA0125
KLF3 Kruppel-like factor 3 (basic)
KPTN kaptin (actin binding protein)
LIN7A lin-7 homolog A (C. elegans)
MAGEF1 melanoma antigen family F1
MBNL3 muscleblind-like splicing regulator 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MGC12488
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase
MLYCD malonyl-CoA decarboxylase
MSMB microseminoprotein, beta-
MTCP1 mature T-cell proliferation 1
MTG1 mitochondrial ribosome-associated GTPase 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NHLRC2 NHL repeat containing 2
NIPAL2 NIPA-like domain containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
NUBPL nucleotide binding protein-like
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PNPLA6 patatin-like phospholipase domain containing 6
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
RAB30 RAB30, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RPIA ribose 5-phosphate isomerase A
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SCRIB scribbled planar cell polarity protein
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGK1 serum/glucocorticoid regulated kinase 1
SHARPIN SHANK-associated RH domain interactor
SLC22A18 solute carrier family 22, member 18
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOBP sine oculis binding protein homolog (Drosophila)
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
SYT17 synaptotagmin XVII
TCTN1 tectonic family member 1
TRAIP TRAF interacting protein
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
WDR3 WD repeat domain 3
WDR60 WD repeat domain 60
XK X-linked Kx blood group
ZBTB3 zinc finger and BTB domain containing 3
ZBTB6 zinc finger and BTB domain containing 6
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMYM1 zinc finger, MYM-type 1
ZNF10 zinc finger protein 10
ZNF23 zinc finger protein 23
ZW10 zw10 kinetochore protein