quinisocaine-4207 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the quinisocaine-4207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACOT11 acyl-CoA thioesterase 11
AKAP5 A kinase (PRKA) anchor protein 5
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ALDOB aldolase B, fructose-bisphosphate
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBC3 BCL2 binding component 3
CCDC186 coiled-coil domain containing 186
CCNG2 cyclin G2
CD58 CD58 molecule
CDC14B cell division cycle 14B
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPN2 carboxypeptidase N, polypeptide 2
CRHR2 corticotropin releasing hormone receptor 2
CTC1 CTS telomere maintenance complex component 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH3 cytohesin 3
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DENND3 DENN/MADD domain containing 3
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOHH deoxyhypusine hydroxylase/monooxygenase
DPF1 D4, zinc and double PHD fingers family 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGR1 early growth response 1
ETNK2 ethanolamine kinase 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FRMD4A FERM domain containing 4A
GABARAPL1 GABA(A) receptor-associated protein like 1
GLRX glutaredoxin (thioltransferase)
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GOLGA8A golgin A8 family, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIPK3 homeodomain interacting protein kinase 3
HIST1H4C histone cluster 1, H4c
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLF hepatic leukemia factor
HOMER3 homer scaffolding protein 3
ICAM1 intercellular adhesion molecule 1
IFFO1 intermediate filament family orphan 1
IL18RAP interleukin 18 receptor accessory protein
IL6 interleukin 6
INHBA inhibin, beta A
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM7A lysine (K)-specific demethylase 7A
LDLR low density lipoprotein receptor
LHX3 LIM homeobox 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYRM9 LYR motif containing 9
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MAP7 microtubule-associated protein 7
MEP1B meprin A, beta
MKL1 megakaryoblastic leukemia (translocation) 1
MST1 macrophage stimulating 1
MTRF1L mitochondrial translational release factor 1-like
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTNG1 netrin G1
NUPR1 nuclear protein, transcriptional regulator, 1
NYNRIN NYN domain and retroviral integrase containing
OTOR otoraplin
PARP6 poly (ADP-ribose) polymerase family, member 6
PCDH11X protocadherin 11 X-linked
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRB1 proline-rich protein BstNI subfamily 1
RAB36 RAB36, member RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS4 regulator of G-protein signaling 4
RPLP2 ribosomal protein, large, P2
RPS3A ribosomal protein S3A
RUFY3 RUN and FYVE domain containing 3
SAMD4A sterile alpha motif domain containing 4A
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETDB1 SET domain, bifurcated 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD4 SMAD family member 4
STC1 stanniocalcin 1
STC2 stanniocalcin 2
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
THOC5 THO complex 5
TLE4 transducin-like enhancer of split 4
TM4SF4 transmembrane 4 L six family member 4
TMEM50B transmembrane protein 50B
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRA2A transformer 2 alpha homolog (Drosophila)
TRIB3 tribbles pseudokinase 3
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WNT5B wingless-type MMTV integration site family, member 5B
WSB1 WD repeat and SOCS box containing 1
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACE angiotensin I converting enzyme
ADAM2 ADAM metallopeptidase domain 2
AEN apoptosis enhancing nuclease
AXIN1 axin 1
BFSP1 beaded filament structural protein 1, filensin
C16ORF59 chromosome 16 open reading frame 59
C1R complement component 1, r subcomponent
C22ORF46 chromosome 22 open reading frame 46
C8A complement component 8, alpha polypeptide
CAPN15 calpain 15
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD70 CD70 molecule
CDT1 chromatin licensing and DNA replication factor 1
CNN1 calponin 1, basic, smooth muscle
CTSD cathepsin D
DDN dendrin
DLK2 delta-like 2 homolog (Drosophila)
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
EPHB6 EPH receptor B6
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPR1 G protein-coupled receptor 1
GSTA3 glutathione S-transferase alpha 3
GTF2I general transcription factor IIi
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HOXA6 homeobox A6
IL17RB interleukin 17 receptor B
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KANSL3 KAT8 regulatory NSL complex subunit 3
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KRT15 keratin 15, type I
KRT20 keratin 20, type I
LIME1 Lck interacting transmembrane adaptor 1
LOC100287590 uncharacterized LOC100287590
LOC157562 uncharacterized LOC157562
LPAR4 lysophosphatidic acid receptor 4
LTC4S leukotriene C4 synthase
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MFSD12 major facilitator superfamily domain containing 12
MGP matrix Gla protein
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MLYCD malonyl-CoA decarboxylase
MN1 meningioma (disrupted in balanced translocation) 1
MRAS muscle RAS oncogene homolog
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
MTCP1 mature T-cell proliferation 1
MYLIP myosin regulatory light chain interacting protein
MYO1F myosin IF
NBEAL2 neurobeachin-like 2
NDP Norrie disease (pseudoglioma)
NRSN2 neurensin 2
NTSR1 neurotensin receptor 1 (high affinity)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PADI1 peptidyl arginine deiminase, type I
PCDH12 protocadherin 12
PLXNA3 plexin A3
PRR7 proline rich 7 (synaptic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S1PR1 sphingosine-1-phosphate receptor 1
SCAMP4 secretory carrier membrane protein 4
SCEL sciellin
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT1 SID1 transmembrane family, member 1
SLC22A18 solute carrier family 22, member 18
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLN sarcolipin
SNHG3 small nucleolar RNA host gene 3
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX12 SRY (sex determining region Y)-box 12
SSBP3 single stranded DNA binding protein 3
TENM4 teneurin transmembrane protein 4
TESPA1 thymocyte expressed, positive selection associated 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMP4 TIMP metallopeptidase inhibitor 4
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMPRSS4 transmembrane protease, serine 4
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TOR4A torsin family 4, member A
TTLL1 tubulin tyrosine ligase-like family member 1
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF408 zinc finger protein 408
ZNF629 zinc finger protein 629