quinpirole-456 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the quinpirole-456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
ALLC allantoicase
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN2 ataxin 2
BAHCC1 BAH domain and coiled-coil containing 1
C7ORF43 chromosome 7 open reading frame 43
CBX8 chromobox homolog 8
CCDC176 coiled-coil domain containing 176
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDK19 cyclin-dependent kinase 19
CDK6 cyclin-dependent kinase 6
CHMP1B charged multivesicular body protein 1B
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COBL cordon-bleu WH2 repeat protein
COL18A1 collagen, type XVIII, alpha 1
CPOX coproporphyrinogen oxidase
DAXX death-domain associated protein
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DEFB126 defensin, beta 126
DOK5 docking protein 5
DRP2 dystrophin related protein 2
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EFS embryonal Fyn-associated substrate
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EXOC2 exocyst complex component 2
FSD1 fibronectin type III and SPRY domain containing 1
GAB2 GRB2-associated binding protein 2
GAS7 growth arrest-specific 7
GATAD1 GATA zinc finger domain containing 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GP2 glycoprotein 2 (zymogen granule membrane)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRIP2 glutamate receptor interacting protein 2
GYPB glycophorin B (MNS blood group)
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IGFBP3 insulin-like growth factor binding protein 3
IL11 interleukin 11
IL15RA interleukin 15 receptor, alpha
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF5B kinesin family member 5B
KLHL36 kelch-like family member 36
KREMEN2 kringle containing transmembrane protein 2
LEMD3 LEM domain containing 3
LGALS8 lectin, galactoside-binding, soluble, 8
LINC00574 long intergenic non-protein coding RNA 574
MBNL2 muscleblind-like splicing regulator 2
MNAT1 MNAT CDK-activating kinase assembly factor 1
MT3 metallothionein 3
MXD4 MAX dimerization protein 4
MYL12B myosin, light chain 12B, regulatory
NAGA N-acetylgalactosaminidase, alpha-
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PHC1 polyhomeotic homolog 1 (Drosophila)
PHIP pleckstrin homology domain interacting protein
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLSCR3 phospholipid scramblase 3
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PTGDS prostaglandin D2 synthase 21kDa (brain)
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RHOBTB3 Rho-related BTB domain containing 3
RHOD ras homolog family member D
RIC8A RIC8 guanine nucleotide exchange factor A
RNF220 ring finger protein 220
RPS28 ribosomal protein S28
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNDC3A RUN domain containing 3A
RUNX2 runt-related transcription factor 2
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SH2B2 SH2B adaptor protein 2
SIDT2 SID1 transmembrane family, member 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLPI secretory leukocyte peptidase inhibitor
SOAT1 sterol O-acyltransferase 1
SZRD1 SUZ RNA binding domain containing 1
TAOK2 TAO kinase 2
TCF3 transcription factor 3
TG thyroglobulin
TGFA transforming growth factor, alpha
THBD thrombomodulin
THBS4 thrombospondin 4
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP53I11 tumor protein p53 inducible protein 11
TRIM29 tripartite motif containing 29
TSHB thyroid stimulating hormone, beta
VAC14 Vac14 homolog (S. cerevisiae)
WDR77 WD repeat domain 77
ZFP36 ZFP36 ring finger protein
ZNF276 zinc finger protein 276
ZNF518A zinc finger protein 518A
ZNF654 zinc finger protein 654
ZNHIT1 zinc finger, HIT-type containing 1

decreased expression

Symbol Name
ACVR2B activin A receptor, type IIB
ADCK3 aarF domain containing kinase 3
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALPK1 alpha-kinase 1
ARSA arylsulfatase A
ASB6 ankyrin repeat and SOCS box containing 6
ATXN8OS ATXN8 opposite strand (non-protein coding)
BAGE B melanoma antigen
BMP10 bone morphogenetic protein 10
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF30 chromosome 5 open reading frame 30
CARTPT CART prepropeptide
CAV3 caveolin 3
CCDC71 coiled-coil domain containing 71
CD300C CD300c molecule
CD53 CD53 molecule
CD83 CD83 molecule
CDK18 cyclin-dependent kinase 18
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNGB3 cyclic nucleotide gated channel beta 3
COCH cochlin
COG7 component of oligomeric golgi complex 7
CRYAB crystallin, alpha B
CYB5R2 cytochrome b5 reductase 2
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DIO3 deiodinase, iodothyronine, type III
DNAI1 dynein, axonemal, intermediate chain 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EGFL6 EGF-like-domain, multiple 6
EGFL7 EGF-like-domain, multiple 7
EVPL envoplakin
FGFBP1 fibroblast growth factor binding protein 1
FOLR2 folate receptor 2 (fetal)
FOXC1 forkhead box C1
FOXD1 forkhead box D1
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GDF9 growth differentiation factor 9
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HAND1 heart and neural crest derivatives expressed 1
HCG9 HLA complex group 9 (non-protein coding)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1D histone cluster 1, H1d
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IRAK4 interleukin-1 receptor-associated kinase 4
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
LIAS lipoic acid synthetase
LMBR1L limb development membrane protein 1-like
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MGC2889 uncharacterized protein MGC2889
MIS18BP1 MIS18 binding protein 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MPZ myelin protein zero
MRPL12 mitochondrial ribosomal protein L12
MTCP1 mature T-cell proliferation 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OTOR otoraplin
PEX26 peroxisomal biogenesis factor 26
PF4 platelet factor 4
PNMAL1 paraneoplastic Ma antigen family-like 1
PQLC2 PQ loop repeat containing 2
PQLC3 PQ loop repeat containing 3
PRPH2 peripherin 2 (retinal degeneration, slow)
PSAT1 phosphoserine aminotransferase 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RNF39 ring finger protein 39
RUFY2 RUN and FYVE domain containing 2
S100A1 S100 calcium binding protein A1
SDC3 syndecan 3
SIGLEC5 sialic acid binding Ig-like lectin 5
SIL1 SIL1 nucleotide exchange factor
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SNHG3 small nucleolar RNA host gene 3
SULT4A1 sulfotransferase family 4A, member 1
SYNDIG1 synapse differentiation inducing 1
T T, brachyury homolog (mouse)
TMEM176A transmembrane protein 176A
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
VSIG4 V-set and immunoglobulin domain containing 4
WNT16 wingless-type MMTV integration site family, member 16
ZNF180 zinc finger protein 180
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF432 zinc finger protein 432
ZNF528 zinc finger protein 528
ZNF668 zinc finger protein 668
ZNHIT2 zinc finger, HIT-type containing 2