quinpirole-7481 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the quinpirole-7481 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ALOX15 arachidonate 15-lipoxygenase
AMPH amphiphysin
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
BMP7 bone morphogenetic protein 7
BRCA2 breast cancer 2, early onset
C19ORF73 chromosome 19 open reading frame 73
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHD3 chromodomain helicase DNA binding protein 3
COL5A1 collagen, type V, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DBF4B DBF4 zinc finger B
DGAT1 diacylglycerol O-acyltransferase 1
DMC1 DNA meiotic recombinase 1
DNAL4 dynein, axonemal, light chain 4
DNPEP aspartyl aminopeptidase
FASTK Fas-activated serine/threonine kinase
FECH ferrochelatase
FLOT1 flotillin 1
HK2 hexokinase 2
HLA-E major histocompatibility complex, class I, E
IFITM1 interferon induced transmembrane protein 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ISG20 interferon stimulated exonuclease gene 20kDa
ITPKB inositol-trisphosphate 3-kinase B
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KAZN kazrin, periplakin interacting protein
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIF1A kinesin family member 1A
KLK8 kallikrein-related peptidase 8
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MATK megakaryocyte-associated tyrosine kinase
MBOAT7 membrane bound O-acyltransferase domain containing 7
MID1 midline 1
MIIP migration and invasion inhibitory protein
MYCNOS MYCN opposite strand
NCOR2 nuclear receptor corepressor 2
NOL6 nucleolar protein 6 (RNA-associated)
NOX1 NADPH oxidase 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NRSN2 neurensin 2
NUMA1 nuclear mitotic apparatus protein 1
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PBX2 pre-B-cell leukemia homeobox 2
PCDHB13 protocadherin beta 13
PCNX pecanex homolog (Drosophila)
PEX19 peroxisomal biogenesis factor 19
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLXNB1 plexin B1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RAB30 RAB30, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RB1 retinoblastoma 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS4 regulator of G-protein signaling 4
RHOQ ras homolog family member Q
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL23 ribosomal protein L23
RPS4Y1 ribosomal protein S4, Y-linked 1
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SIRT3 sirtuin 3
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SOX4 SRY (sex determining region Y)-box 4
SPN sialophorin
SVIL supervillin
SYNJ2 synaptojanin 2
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TJAP1 tight junction associated protein 1 (peripheral)
TLE4 transducin-like enhancer of split 4
TMC7 transmembrane channel-like 7
TREX1 three prime repair exonuclease 1
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
TTLL5 tubulin tyrosine ligase-like family member 5
VIPR2 vasoactive intestinal peptide receptor 2
WDTC1 WD and tetratricopeptide repeats 1
XDH xanthine dehydrogenase
YY1 YY1 transcription factor
ZNF428 zinc finger protein 428
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AFF4 AF4/FMR2 family, member 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APH1A APH1A gamma secretase subunit
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BAGE B melanoma antigen
BAX BCL2-associated X protein
BBS10 Bardet-Biedl syndrome 10
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF30 chromosome 11 open reading frame 30
CBR3 carbonyl reductase 3
CCNE1 cyclin E1
CDK3 cyclin-dependent kinase 3
CERK ceramide kinase
CFD complement factor D (adipsin)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF13 DDB1 and CUL4 associated factor 13
DDIT3 DNA-damage-inducible transcript 3
DGKE diacylglycerol kinase, epsilon 64kDa
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ERCC4 excision repair cross-complementation group 4
FAM184A family with sequence similarity 184, member A
FCHO1 FCH domain only 1
GPR27 G protein-coupled receptor 27
GPR87 G protein-coupled receptor 87
GRAMD4 GRAM domain containing 4
GSTT1 glutathione S-transferase theta 1
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST1H2BI histone cluster 1, H2bi
HMOX1 heme oxygenase 1
HPN hepsin
HTRA1 HtrA serine peptidase 1
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL17RA interleukin 17 receptor A
INCENP inner centromere protein antigens 135/155kDa
INSIG2 insulin induced gene 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KRT86 keratin 86, type II
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMCD1 LIM and cysteine-rich domains 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MRPL52 mitochondrial ribosomal protein L52
MYO1F myosin IF
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OLFML3 olfactomedin-like 3
PARP12 poly (ADP-ribose) polymerase family, member 12
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF121 ring finger protein 121
RNF126P1 ring finger protein 126 pseudogene 1
RPAP2 RNA polymerase II associated protein 2
SCAMP5 secretory carrier membrane protein 5
SCD5 stearoyl-CoA desaturase 5
SCHIP1 schwannomin interacting protein 1
SCN1B sodium channel, voltage gated, type I beta subunit
SH2B3 SH2B adaptor protein 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SMA4 glucuronidase, beta pseudogene
SOX3 SRY (sex determining region Y)-box 3
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TEX30 testis expressed 30
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMPRSS4 transmembrane protease, serine 4
TRAPPC11 trafficking protein particle complex 11
UNC13B unc-13 homolog B (C. elegans)
WDR4 WD repeat domain 4
WWC2 WW and C2 domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF184 zinc finger protein 184
ZNF250 zinc finger protein 250
ZNF32 zinc finger protein 32
ZNF480 zinc finger protein 480
ZNF557 zinc finger protein 557