quipazine-2782 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the quipazine-2782 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ANP32A-IT1 ANP32A intronic transcript 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ART1 ADP-ribosyltransferase 1
BIRC7 baculoviral IAP repeat containing 7
C1ORF61 chromosome 1 open reading frame 61
C1ORF95 chromosome 1 open reading frame 95
C6 complement component 6
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCDC69 coiled-coil domain containing 69
CHRNG cholinergic receptor, nicotinic, gamma (muscle)
COL7A1 collagen, type VII, alpha 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CUZD1 CUB and zona pellucida-like domains 1
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DLG5 discs, large homolog 5 (Drosophila)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK6 dedicator of cytokinesis 6
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELSPBP1 epididymal sperm binding protein 1
ETV5 ets variant 5
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP8 FK506 binding protein 8, 38kDa
GGT1 gamma-glutamyltransferase 1
GPER1 G protein-coupled estrogen receptor 1
GRPR gastrin-releasing peptide receptor
HCRP1 hepatocellular carcinoma-related HCRP1
HIST2H2AA3 histone cluster 2, H2aa3
HOMER3 homer scaffolding protein 3
ICA1 islet cell autoantigen 1, 69kDa
IDS iduronate 2-sulfatase
IL6R interleukin 6 receptor
IRF2 interferon regulatory factor 2
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
MAP4 microtubule-associated protein 4
MED16 mediator complex subunit 16
MSR1 macrophage scavenger receptor 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MX1 MX dynamin-like GTPase 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
N4BP1 NEDD4 binding protein 1
NF2 neurofibromin 2 (merlin)
NME5 NME/NM23 family member 5
NR2F1 nuclear receptor subfamily 2, group F, member 1
NRGN neurogranin (protein kinase C substrate, RC3)
PCDHGA8 protocadherin gamma subfamily A, 8
PEAK1 pseudopodium-enriched atypical kinase 1
PGBD5 piggyBac transposable element derived 5
PHF14 PHD finger protein 14
PLAGL1 pleiomorphic adenoma gene-like 1
PLCD1 phospholipase C, delta 1
POLM polymerase (DNA directed), mu
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PROSC proline synthetase co-transcribed homolog (bacterial)
PSD3 pleckstrin and Sec7 domain containing 3
PTHLH parathyroid hormone-like hormone
PVT1 Pvt1 oncogene (non-protein coding)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6B RAB6B, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGD Ras-related GTP binding D
SIGLEC7 sialic acid binding Ig-like lectin 7
SIM2 single-minded family bHLH transcription factor 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNTG1 syntrophin, gamma 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX19 T-box 19
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNNT3 troponin T type 3 (skeletal, fast)
TRAK1 trafficking protein, kinesin binding 1
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VASH1 vasohibin 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
YIPF4 Yip1 domain family, member 4
ZCCHC14 zinc finger, CCHC domain containing 14
ZER1 zyg-11 related, cell cycle regulator
ZFAND5 zinc finger, AN1-type domain 5
ZFPL1 zinc finger protein-like 1
ZNF202 zinc finger protein 202
ZNF37BP zinc finger protein 37B, pseudogene
ZNF821 zinc finger protein 821
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADCY7 adenylate cyclase 7
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMCX2 armadillo repeat containing, X-linked 2
ASIC3 acid sensing (proton gated) ion channel 3
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
C17ORF80 chromosome 17 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CCDC68 coiled-coil domain containing 68
CCNO cyclin O
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD83 CD83 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPJ centromere protein J
CHRM3 cholinergic receptor, muscarinic 3
CLCN6 chloride channel, voltage-sensitive 6
CNR2 cannabinoid receptor 2 (macrophage)
CORO7 coronin 7
CXADR coxsackie virus and adenovirus receptor
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DOCK1 dedicator of cytokinesis 1
DUSP2 dual specificity phosphatase 2
EDAR ectodysplasin A receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
F2R coagulation factor II (thrombin) receptor
FAM120C family with sequence similarity 120C
FAM212B family with sequence similarity 212, member B
FAM50B family with sequence similarity 50, member B
FBXL6 F-box and leucine-rich repeat protein 6
FGF23 fibroblast growth factor 23
FKBP10 FK506 binding protein 10, 65 kDa
FMOD fibromodulin
FOXN2 forkhead box N2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA4 GATA binding protein 4
GFI1 growth factor independent 1 transcription repressor
GK3P glycerol kinase 3 pseudogene
GLS2 glutaminase 2 (liver, mitochondrial)
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H4F histone cluster 1, H4f
HOXC11 homeobox C11
HOXC5 homeobox C5
IL22 interleukin 22
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM5C lysine (K)-specific demethylase 5C
KEL Kell blood group, metallo-endopeptidase
KLHL21 kelch-like family member 21
KLHL28 kelch-like family member 28
MAPK8 mitogen-activated protein kinase 8
MFAP2 microfibrillar-associated protein 2
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP2 matrix metallopeptidase 2
MYO1F myosin IF
MYOZ3 myozenin 3
N4BP3 NEDD4 binding protein 3
NCALD neurocalcin delta
NPFFR1 neuropeptide FF receptor 1
PLCG1 phospholipase C, gamma 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS22 protease, serine, 22
RAB3D RAB3D, member RAS oncogene family
SAYSD1 SAYSVFN motif domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A8 solute carrier family 12, member 8
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLIT2 slit homolog 2 (Drosophila)
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SP1 Sp1 transcription factor
SPINK5 serine peptidase inhibitor, Kazal type 5
STIM1 stromal interaction molecule 1
STK16 serine/threonine kinase 16
TCTN2 tectonic family member 2
TMEM121 transmembrane protein 121
TWISTNB TWIST neighbor
TYRP1 tyrosinase-related protein 1
WDR4 WD repeat domain 4
YY2 YY2 transcription factor
ZBTB22 zinc finger and BTB domain containing 22
ZBTB33 zinc finger and BTB domain containing 33
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF205 zinc finger protein 205
ZSCAN2 zinc finger and SCAN domain containing 2