quipazine-5887 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the quipazine-5887 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM2 absent in melanoma 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARMC6 armadillo repeat containing 6
ARNTL aryl hydrocarbon receptor nuclear translocator-like
AUTS2 autism susceptibility candidate 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP7 bone morphogenetic protein 7
CABP2 calcium binding protein 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALML3 calmodulin-like 3
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL27 chemokine (C-C motif) ligand 27
CCNJ cyclin J
CCNO cyclin O
CDK13 cyclin-dependent kinase 13
CELF2 CUGBP, Elav-like family member 2
CISH cytokine inducible SH2-containing protein
COL4A1 collagen, type IV, alpha 1
DESI2 desumoylating isopeptidase 2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMID1 EMI domain containing 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HEXIM1 hexamethylene bis-acetamide inducible 1
HIST1H4D histone cluster 1, H4d
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICOSLG inducible T-cell co-stimulator ligand
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL11 interleukin 11
INADL InaD-like (Drosophila)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCTD17 potassium channel tetramerization domain containing 17
KLHL36 kelch-like family member 36
KYNU kynureninase
LOC390998 ribosomal protein L10 pseudogene
LOC644450 uncharacterized LOC644450
LPAR4 lysophosphatidic acid receptor 4
LRRC61 leucine rich repeat containing 61
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MATN3 matrilin 3
MBNL2 muscleblind-like splicing regulator 2
MCC mutated in colorectal cancers
MMRN2 multimerin 2
MNDA myeloid cell nuclear differentiation antigen
MTA2 metastasis associated 1 family, member 2
NEK11 NIMA-related kinase 11
NFX1 nuclear transcription factor, X-box binding 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSBPL10 oxysterol binding protein-like 10
PAX2 paired box 2
PDE10A phosphodiesterase 10A
PDE4DIP phosphodiesterase 4D interacting protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLD2 phospholipase D2
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAD51B RAD51 paralog B
RAD52 RAD52 homolog (S. cerevisiae)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS17 regulator of G-protein signaling 17
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SCARF1 scavenger receptor class F, member 1
SCIN scinderin
SIKE1 suppressor of IKBKE 1
SLC16A6 solute carrier family 16, member 6
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC46A3 solute carrier family 46, member 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOS1 son of sevenless homolog 1 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPN sialophorin
STX7 syntaxin 7
SYCP2 synaptonemal complex protein 2
TCF12 transcription factor 12
TCF15 transcription factor 15 (basic helix-loop-helix)
TP53I11 tumor protein p53 inducible protein 11
TSPAN8 tetraspanin 8
TSSK2 testis-specific serine kinase 2
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VNN2 vanin 2
WDR62 WD repeat domain 62
WNT7A wingless-type MMTV integration site family, member 7A
ZBTB22 zinc finger and BTB domain containing 22
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF117 zinc finger protein 117
ZNF358 zinc finger protein 358

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
APOLD1 apolipoprotein L domain containing 1
ATG7 autophagy related 7
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCORL1 BCL6 corepressor-like 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTC betacellulin
C17ORF70 chromosome 17 open reading frame 70
CCNT1 cyclin T1
CDADC1 cytidine and dCMP deaminase domain containing 1
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHMP7 charged multivesicular body protein 7
CIR1 corepressor interacting with RBPJ, 1
CNTNAP3B contactin associated protein-like 3B
CST6 cystatin E/M
CXORF56 chromosome X open reading frame 56
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ERCC1 excision repair cross-complementation group 1
FAM172A family with sequence similarity 172, member A
FAM53B family with sequence similarity 53, member B
FBXL15 F-box and leucine-rich repeat protein 15
GALT galactose-1-phosphate uridylyltransferase
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GRWD1 glutamate-rich WD repeat containing 1
HAMP hepcidin antimicrobial peptide
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HOXC10 homeobox C10
IGFLR1 IGF-like family receptor 1
IL4R interleukin 4 receptor
IL6 interleukin 6
ITPKC inositol-trisphosphate 3-kinase C
KIAA0355 KIAA0355
KRT31 keratin 31, type I
KRT75 keratin 75, type II
LIG1 ligase I, DNA, ATP-dependent
LIMS2 LIM and senescent cell antigen-like domains 2
LRP3 low density lipoprotein receptor-related protein 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD3 LY6/PLAUR domain containing 3
LZTR1 leucine-zipper-like transcription regulator 1
MAP6D1 MAP6 domain containing 1
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MCRS1 microspherule protein 1
MCTP2 multiple C2 domains, transmembrane 2
NPM3 nucleophosmin/nucleoplasmin 3
NRSN2 neurensin 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NXPE3 neurexophilin and PC-esterase domain family, member 3
PALMD palmdelphin
PARD6A par-6 family cell polarity regulator alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PRPH peripherin
PRSS16 protease, serine, 16 (thymus)
PTGES2 prostaglandin E synthase 2
PTGFR prostaglandin F receptor (FP)
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB17 RAB17, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGCC regulator of cell cycle
RPL13P5 ribosomal protein L13 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAMP4 secretory carrier membrane protein 4
SCN1B sodium channel, voltage gated, type I beta subunit
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SETD8 SET domain containing (lysine methyltransferase) 8
SGK2 serum/glucocorticoid regulated kinase 2
SHPK sedoheptulokinase
SIK1 salt-inducible kinase 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLITRK5 SLIT and NTRK-like family, member 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN3 transgelin 3
TCTN1 tectonic family member 1
TENM4 teneurin transmembrane protein 4
TESK2 testis-specific kinase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
ZNF10 zinc finger protein 10
ZNF204P zinc finger protein 204, pseudogene
ZNF215 zinc finger protein 215
ZNF230 zinc finger protein 230
ZNF35 zinc finger protein 35
ZNF592 zinc finger protein 592
ZNF671 zinc finger protein 671