rac1 Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)|The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 5879)
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Genes

129 proteins co-occuring with the biological term rac1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACTN4 actinin, alpha 4
ADD1 adducin 1 (alpha)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AQP9 aquaporin 9
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP22 Rho GTPase activating protein 22
ARHGAP31 Rho GTPase activating protein 31
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ATF2 activating transcription factor 2
BAD BCL2-associated agonist of cell death
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD28 CD28 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CFL1 cofilin 1 (non-muscle)
CHN2 chimerin 2
CLASP2 cytoplasmic linker associated protein 2
CREB1 cAMP responsive element binding protein 1
CRYAB crystallin, alpha B
CSNK1E casein kinase 1, epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCR4 chemokine (C-X-C motif) receptor 4
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCD dermcidin
DCX doublecortin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DLG4 discs, large homolog 4 (Drosophila)
DOCK1 dedicator of cytokinesis 1
DOCK6 dedicator of cytokinesis 6
DOCK7 dedicator of cytokinesis 7
DYNLT1 dynein, light chain, Tctex-type 1
ECT2 epithelial cell transforming 2
EGFR epidermal growth factor receptor
EPHA2 EPH receptor A2
EZR ezrin
FOXO3 forkhead box O3
GAB1 GRB2-associated binding protein 1
GMFG glia maturation factor, gamma
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GSK3B glycogen synthase kinase 3 beta
IQGAP1 IQ motif containing GTPase activating protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JUN jun proto-oncogene
KALRN kalirin, RhoGEF kinase
KDR kinase insert domain receptor
LIMK2 LIM domain kinase 2
LTB4R2 leukotriene B4 receptor 2
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK4 mitogen-activated protein kinase 4
MAPK6 mitogen-activated protein kinase 6
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MITF microphthalmia-associated transcription factor
MSN moesin
MYL12B myosin, light chain 12B, regulatory
MYL9 myosin, light chain 9, regulatory
NET1 neuroepithelial cell transforming 1
NF2 neurofibromin 2 (merlin)
NGEF neuronal guanine nucleotide exchange factor
NOS3 nitric oxide synthase 3 (endothelial cell)
NOXA1 NADPH oxidase activator 1
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NREP neuronal regeneration related protein
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
PACSIN1 protein kinase C and casein kinase substrate in neurons 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PARD3 par-3 family cell polarity regulator
PARVA parvin, alpha
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLD2 phospholipase D2
PLK1 polo-like kinase 1
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRDX6 peroxiredoxin 6
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCD protein kinase C, delta
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RDX radixin
RHOA ras homolog family member A
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SDCBP syndecan binding protein (syntenin)
SGK1 serum/glucocorticoid regulated kinase 1
SH3BP2 SH3-domain binding protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHCBP1 SHC SH2-domain binding protein 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STMN1 stathmin 1
SYK spleen tyrosine kinase
TIAM1 T-cell lymphoma invasion and metastasis 1
TIAM2 T-cell lymphoma invasion and metastasis 2
TRIO trio Rho guanine nucleotide exchange factor
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VIM vimentin
WASF1 WAS protein family, member 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa