racecadotril-1782 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the racecadotril-1782 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABHD2 abhydrolase domain containing 2
ACTC1 actin, alpha, cardiac muscle 1
AIF1 allograft inflammatory factor 1
APOM apolipoprotein M
ARHGAP1 Rho GTPase activating protein 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATXN2L ataxin 2-like
BAIAP2 BAI1-associated protein 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CADM3 cell adhesion molecule 3
CCDC33 coiled-coil domain containing 33
CD5 CD5 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHN2 chimerin 2
CLDN6 claudin 6
CLTA clathrin, light chain A
COPS6 COP9 signalosome subunit 6
CRMP1 collapsin response mediator protein 1
CTNS cystinosin, lysosomal cystine transporter
CYB561 cytochrome b561
EFNB3 ephrin-B3
ELMO2 engulfment and cell motility 2
FAM105A family with sequence similarity 105, member A
FAM153A family with sequence similarity 153, member A
FAM89B family with sequence similarity 89, member B
FBXL15 F-box and leucine-rich repeat protein 15
FBXL18 F-box and leucine-rich repeat protein 18
FNDC3A fibronectin type III domain containing 3A
GALR3 galanin receptor 3
GATA2 GATA binding protein 2
GCDH glutaryl-CoA dehydrogenase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIPK2 homeodomain interacting protein kinase 2
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
ITGB5 integrin, beta 5
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIF3C kinesin family member 3C
KIF5A kinesin family member 5A
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAGED2 melanoma antigen family D2
MBTD1 mbt domain containing 1
MED18 mediator complex subunit 18
MOB3B MOB kinase activator 3B
MTRF1L mitochondrial translational release factor 1-like
MYO9B myosin IXB
NADK NAD kinase
NDRG2 NDRG family member 2
NLRP3 NLR family, pyrin domain containing 3
NOP16 NOP16 nucleolar protein
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OVGP1 oviductal glycoprotein 1, 120kDa
PARM1 prostate androgen-regulated mucin-like protein 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDH17 protocadherin 17
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POMT1 protein-O-mannosyltransferase 1
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PPP6R2 protein phosphatase 6, regulatory subunit 2
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS12 regulator of G-protein signaling 12
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPL18 ribosomal protein L18
RPS9 ribosomal protein S9
S1PR4 sphingosine-1-phosphate receptor 4
SCARB2 scavenger receptor class B, member 2
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC45A2 solute carrier family 45, member 2
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SPATA5L1 spermatogenesis associated 5-like 1
STAP2 signal transducing adaptor family member 2
SUPT7L suppressor of Ty 7 (S. cerevisiae)-like
TEX2 testis expressed 2
TOP3A topoisomerase (DNA) III alpha
TRADD TNFRSF1A-associated via death domain
TRBC1 T cell receptor beta constant 1
TRIM66 tripartite motif containing 66
TRMT61A tRNA methyltransferase 61A
TSC22D3 TSC22 domain family, member 3
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
VPRBP Vpr (HIV-1) binding protein
YTHDC1 YTH domain containing 1
ZNF185 zinc finger protein 185 (LIM domain)
ZNF764 zinc finger protein 764

decreased expression

Symbol Name
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3
AGPS alkylglycerone phosphate synthase
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AUP1 ancient ubiquitous protein 1
AVEN apoptosis, caspase activation inhibitor
BAHD1 bromo adjacent homology domain containing 1
BCL10 B-cell CLL/lymphoma 10
CA2 carbonic anhydrase II
CAPN15 calpain 15
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CCDC130 coiled-coil domain containing 130
CD302 CD302 molecule
CD9 CD9 molecule
CDCA3 cell division cycle associated 3
CDK8 cyclin-dependent kinase 8
CDK9 cyclin-dependent kinase 9
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDR2 cerebellar degeneration-related protein 2, 62kDa
CFAP20 cilia and flagella associated protein 20
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CS citrate synthase
CXORF40A chromosome X open reading frame 40A
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DERL1 derlin 1
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DMTF1 cyclin D binding myb-like transcription factor 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
ENO2 enolase 2 (gamma, neuronal)
EPS8 epidermal growth factor receptor pathway substrate 8
ERCC3 excision repair cross-complementation group 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM189B family with sequence similarity 189, member B
FBXO5 F-box protein 5
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FPGS folylpolyglutamate synthase
GBAS glioblastoma amplified sequence
GPR183 G protein-coupled receptor 183
HARS histidyl-tRNA synthetase
HIST3H2A histone cluster 3, H2a
HOMER1 homer scaffolding protein 1
HOOK2 hook microtubule-tethering protein 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPE1 heat shock 10kDa protein 1
IRF7 interferon regulatory factor 7
JOSD1 Josephin domain containing 1
KIAA1551 KIAA1551
KIZ kizuna centrosomal protein
LACTB2 lactamase, beta 2
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
LAS1L LAS1-like (S. cerevisiae)
MFSD12 major facilitator superfamily domain containing 12
MOSPD3 motile sperm domain containing 3
NCAPH non-SMC condensin I complex, subunit H
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
NEK11 NIMA-related kinase 11
NMB neuromedin B
NOP10 NOP10 ribonucleoprotein
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAQR3 progestin and adipoQ receptor family member III
PCDHGB5 protocadherin gamma subfamily B, 5
PCNA proliferating cell nuclear antigen
PDHX pyruvate dehydrogenase complex, component X
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PES1 pescadillo ribosomal biogenesis factor 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PPARG peroxisome proliferator-activated receptor gamma
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRPF39 pre-mRNA processing factor 39
PXMP2 peroxisomal membrane protein 2, 22kDa
RARS arginyl-tRNA synthetase
RIC8B RIC8 guanine nucleotide exchange factor B
SLC25A40 solute carrier family 25, member 40
SMAD7 SMAD family member 7
SMNDC1 survival motor neuron domain containing 1
SNX10 sorting nexin 10
SNX6 sorting nexin 6
SUCLG1 succinate-CoA ligase, alpha subunit
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM45A transmembrane protein 45A
TMEM53 transmembrane protein 53
TOE1 target of EGR1, member 1 (nuclear)
TOM1L1 target of myb1 (chicken)-like 1
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TTC27 tetratricopeptide repeat domain 27
TWF2 twinfilin actin binding protein 2
UBE3C ubiquitin protein ligase E3C
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
WDR3 WD repeat domain 3
WDR82 WD repeat domain 82
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YEATS4 YEATS domain containing 4
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586
ZSCAN9 zinc finger and SCAN domain containing 9
ZWINT ZW10 interacting kinetochore protein