| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
198 genes differentially expressed following the racecadotril-5755 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| APC | adenomatous polyposis coli |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASTN2 | astrotactin 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP10A | ATPase, class V, type 10A |
| BBC3 | BCL2 binding component 3 |
| BCL3 | B-cell CLL/lymphoma 3 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C3AR1 | complement component 3a receptor 1 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CCDC85C | coiled-coil domain containing 85C |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CD53 | CD53 molecule |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DFNB31 | deafness, autosomal recessive 31 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DKFZP434C153 | DKFZP434C153 protein |
| DMBT1 | deleted in malignant brain tumors 1 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FABP4 | fatty acid binding protein 4, adipocyte |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GHRHR | growth hormone releasing hormone receptor |
| GSTM5 | glutathione S-transferase mu 5 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| HOXB3 | homeobox B3 |
| HPCAL4 | hippocalcin like 4 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL1RN | interleukin 1 receptor antagonist |
| IL2 | interleukin 2 |
| ING1 | inhibitor of growth family, member 1 |
| ING4 | inhibitor of growth family, member 4 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KIAA1644 | KIAA1644 |
| KLHL22 | kelch-like family member 22 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MPZ | myelin protein zero |
| MTAP | methylthioadenosine phosphorylase |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NELL2 | NEL-like 2 (chicken) |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OR2B2 | olfactory receptor, family 2, subfamily B, member 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDH12 | protocadherin 12 |
| PDE12 | phosphodiesterase 12 |
| PHF20 | PHD finger protein 20 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PODNL1 | podocan-like 1 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| REC8 | REC8 meiotic recombination protein |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF39 | ring finger protein 39 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SFTPB | surfactant protein B |
| SIRT5 | sirtuin 5 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SNCAIP | synuclein, alpha interacting protein |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SRPK2 | SRSF protein kinase 2 |
| SULF1 | sulfatase 1 |
| THBD | thrombomodulin |
| TJP3 | tight junction protein 3 |
| TMEM180 | transmembrane protein 180 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPAN32 | tetraspanin 32 |
| U2SURP | U2 snRNP-associated SURP domain containing |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| USP29 | ubiquitin specific peptidase 29 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZNF225 | zinc finger protein 225 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ANXA10 | annexin A10 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1RL | complement component 1, r subcomponent-like |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNJL | cyclin J-like |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CLDN14 | claudin 14 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGFL7 | EGF-like-domain, multiple 7 |
| FAM102A | family with sequence similarity 102, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPX2 | glutathione peroxidase 2 |
| HIST1H3G | histone cluster 1, H3g |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HOXA7 | homeobox A7 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA14 | interferon, alpha 14 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| KRT9 | keratin 9, type I |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINS | lines homolog (Drosophila) |
| LMO7 | LIM domain 7 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MBTD1 | mbt domain containing 1 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRAS | muscle RAS oncogene homolog |
| NDRG4 | NDRG family member 4 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OTUD3 | OTU deubiquitinase 3 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRAMEF11 | PRAME family member 11 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR14L | proline rich 14-like |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCG2 | secretogranin II |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMA4 | glucuronidase, beta pseudogene |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STEAP4 | STEAP family member 4 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TENM1 | teneurin transmembrane protein 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM209 | transmembrane protein 209 |
| TNS2 | tensin 2 |
| TUBB2B | tubulin, beta 2B class IIb |
| UBTD1 | ubiquitin domain containing 1 |
| USP19 | ubiquitin specific peptidase 19 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT2 | xylosyltransferase II |
| ZNF362 | zinc finger protein 362 |
| ZNF671 | zinc finger protein 671 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
