| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the racecadotril-6231 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AIM1L | absent in melanoma 1-like |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CCKBR | cholecystokinin B receptor |
| CCNO | cyclin O |
| CCPG1 | cell cycle progression 1 |
| CDC25A | cell division cycle 25A |
| COL4A4 | collagen, type IV, alpha 4 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EXOC7 | exocyst complex component 7 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| GIMAP5 | GTPase, IMAP family member 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-C | major histocompatibility complex, class I, C |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL22 | interleukin 22 |
| IL6R | interleukin 6 receptor |
| ING4 | inhibitor of growth family, member 4 |
| IRF4 | interferon regulatory factor 4 |
| JRK | Jrk homolog (mouse) |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KHSRP | KH-type splicing regulatory protein |
| LDB1 | LIM domain binding 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMNB1 | lamin B1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MICALL1 | MICAL-like 1 |
| MINK1 | misshapen-like kinase 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MUC1 | mucin 1, cell surface associated |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKD3 | protein kinase D3 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RANBP3 | RAN binding protein 3 |
| RARG | retinoic acid receptor, gamma |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAMD9 | sterile alpha motif domain containing 9 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SRPX | sushi-repeat containing protein, X-linked |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK3 | serine/threonine kinase 3 |
| STRN | striatin, calmodulin binding protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TAF1 | TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPP1 | tripeptidyl peptidase I |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM14 | tripartite motif containing 14 |
| TRMT1 | tRNA methyltransferase 1 homolog (S. cerevisiae) |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TUBG2 | tubulin, gamma 2 |
| ULBP2 | UL16 binding protein 2 |
| VEGFC | vascular endothelial growth factor C |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF273 | zinc finger protein 273 |
| ZNF318 | zinc finger protein 318 |
| ZNF329 | zinc finger protein 329 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF576 | zinc finger protein 576 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATF3 | activating transcription factor 3 |
| BBC3 | BCL2 binding component 3 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC170 | coiled-coil domain containing 170 |
| CENPT | centromere protein T |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CTAGE9 | CTAGE family, member 9 |
| CTSK | cathepsin K |
| CXORF56 | chromosome X open reading frame 56 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FBRS | fibrosin |
| FBXO31 | F-box protein 31 |
| FCHO1 | FCH domain only 1 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GPR19 | G protein-coupled receptor 19 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HTRA1 | HtrA serine peptidase 1 |
| IL17RA | interleukin 17 receptor A |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| JADE3 | jade family PHD finger 3 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIFAP3 | kinesin-associated protein 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB2 | lamin B2 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MITF | microphthalmia-associated transcription factor |
| MNS1 | meiosis-specific nuclear structural 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NCAM2 | neural cell adhesion molecule 2 |
| NLK | nemo-like kinase |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLD3 | phospholipase D family, member 3 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PRR14L | proline rich 14-like |
| PRR15L | proline rich 15-like |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RBL1 | retinoblastoma-like 1 |
| RNF219 | ring finger protein 219 |
| SCAI | suppressor of cancer cell invasion |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHARPIN | SHANK-associated RH domain interactor |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TBL3 | transducin (beta)-like 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM66 | tripartite motif containing 66 |
| UBXN6 | UBX domain protein 6 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR19 | WD repeat domain 19 |
| ZNF141 | zinc finger protein 141 |
| ZNF23 | zinc finger protein 23 |
| ZNF552 | zinc finger protein 552 |
| ZNF573 | zinc finger protein 573 |
| ZNF768 | zinc finger protein 768 |
