rad52 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description RAD52 homolog (S. cerevisiae)|The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014] (NCBI Entrez Gene Database, 5893)
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Genes

13 genes co-occuring with the biological term rad52 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BRCA2 breast cancer 2, early onset
ERCC3 excision repair cross-complementation group 3
FEN1 flap structure-specific endonuclease 1
LIG4 ligase IV, DNA, ATP-dependent
MIR302A microRNA 302a
MUS81 MUS81 structure-specific endonuclease subunit
OGG1 8-oxoguanine DNA glycosylase
PTEN phosphatase and tensin homolog
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L RAD54-like (S. cerevisiae)
RPA1 replication protein A1, 70kDa
WRN Werner syndrome, RecQ helicase-like