raloxifene-202 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the raloxifene-202 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADAM22 ADAM metallopeptidase domain 22
AGRN agrin
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARNT aryl hydrocarbon receptor nuclear translocator
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ATR ATR serine/threonine kinase
BAIAP2 BAI1-associated protein 2
C21ORF2 chromosome 21 open reading frame 2
CA11 carbonic anhydrase XI
CADM1 cell adhesion molecule 1
CHD9 chromodomain helicase DNA binding protein 9
CORO1B coronin, actin binding protein, 1B
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTC1 CTS telomere maintenance complex component 1
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DUSP22 dual specificity phosphatase 22
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXTL3 exostosin-like glycosyltransferase 3
FAM114A2 family with sequence similarity 114, member A2
FBLN1 fibulin 1
FKBP2 FK506 binding protein 2, 13kDa
FXR2 fragile X mental retardation, autosomal homolog 2
GALR3 galanin receptor 3
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPR107 G protein-coupled receptor 107
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HEG1 heart development protein with EGF-like domains 1
HIST1H2BD histone cluster 1, H2bd
HLA-E major histocompatibility complex, class I, E
IGKC immunoglobulin kappa constant
IL15RA interleukin 15 receptor, alpha
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITSN1 intersectin 1 (SH3 domain protein)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KHNYN KH and NYN domain containing
KYNU kynureninase
LENEP lens epithelial protein
LHX2 LIM homeobox 2
LRP6 low density lipoprotein receptor-related protein 6
MALT1 MALT1 paracaspase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MMP19 matrix metallopeptidase 19
MSH3 mutS homolog 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDRG2 NDRG family member 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NF1 neurofibromin 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PADI2 peptidyl arginine deiminase, type II
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase
PCSK7 proprotein convertase subtilisin/kexin type 7
PCTP phosphatidylcholine transfer protein
PDGFA platelet-derived growth factor alpha polypeptide
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
PLA2G12A phospholipase A2, group XIIA
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PRDM11 PR domain containing 11
RBBP6 retinoblastoma binding protein 6
RBL2 retinoblastoma-like 2
RPS17P5 ribosomal protein S17 pseudogene 5
SH3BGR SH3 domain binding glutamate-rich protein
SHB Src homology 2 domain containing adaptor protein B
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SOD2 superoxide dismutase 2, mitochondrial
TEK TEK tyrosine kinase, endothelial
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMCC1 transmembrane and coiled-coil domain family 1
TMEM127 transmembrane protein 127
TPI1 triosephosphate isomerase 1
TRA2A transformer 2 alpha homolog (Drosophila)
TRABD TraB domain containing
TRAK1 trafficking protein, kinesin binding 1
TRAPPC12 trafficking protein particle complex 12
TRD T cell receptor delta locus
TRIM2 tripartite motif containing 2
TSN translin
UNC93B1 unc-93 homolog B1 (C. elegans)
UPP1 uridine phosphorylase 1
USP20 ubiquitin specific peptidase 20
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
ZFAND5 zinc finger, AN1-type domain 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYM1 zinc finger, MYM-type 1
ZNF331 zinc finger protein 331
ZNF473 zinc finger protein 473
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCK3 aarF domain containing kinase 3
AEN apoptosis enhancing nuclease
AHSP alpha hemoglobin stabilizing protein
AMN amnion associated transmembrane protein
ARMT1 acidic residue methyltransferase 1
ASPA aspartoacylase
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BEST2 bestrophin 2
C19ORF40 chromosome 19 open reading frame 40
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CALB2 calbindin 2
CAV3 caveolin 3
CD48 CD48 molecule
CD5 CD5 molecule
CDHR2 cadherin-related family member 2
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CENPO centromere protein O
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHGA chromogranin A
CLSTN3 calsyntenin 3
CNTD2 cyclin N-terminal domain containing 2
COBL cordon-bleu WH2 repeat protein
COLEC12 collectin sub-family member 12
CXCL9 chemokine (C-X-C motif) ligand 9
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ERCC2 excision repair cross-complementation group 2
EXOSC9 exosome component 9
FCHSD2 FCH and double SH3 domains 2
FLRT1 fibronectin leucine rich transmembrane protein 1
FUT2 fucosyltransferase 2 (secretor status included)
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GFRA1 GDNF family receptor alpha 1
GPA33 glycoprotein A33 (transmembrane)
GPR27 G protein-coupled receptor 27
GRM4 glutamate receptor, metabotropic 4
GSTP1 glutathione S-transferase pi 1
HAMP hepcidin antimicrobial peptide
HIST1H1C histone cluster 1, H1c
HIST1H4G histone cluster 1, H4g
HOXC4 homeobox C4
IL7R interleukin 7 receptor
INA internexin neuronal intermediate filament protein, alpha
KLHL36 kelch-like family member 36
KRI1 KRI1 homolog (S. cerevisiae)
LGMN legumain
LONRF3 LON peptidase N-terminal domain and ring finger 3
LY86 lymphocyte antigen 86
MT3 metallothionein 3
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
OR1F1 olfactory receptor, family 1, subfamily F, member 1
PADI1 peptidyl arginine deiminase, type I
PCDHB3 protocadherin beta 3
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PKD2L1 polycystic kidney disease 2-like 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLCD1 phospholipase C, delta 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
RNF121 ring finger protein 121
S1PR4 sphingosine-1-phosphate receptor 4
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC26A10 solute carrier family 26, member 10
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SND1-IT1 SND1 intronic transcript 1
SOBP sine oculis binding protein homolog (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
SRPK3 SRSF protein kinase 3
ST5 suppression of tumorigenicity 5
STAB2 stabilin 2
STAC SH3 and cysteine rich domain
STARD5 StAR-related lipid transfer (START) domain containing 5
STX5 syntaxin 5
SYNPO synaptopodin
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGM5 transglutaminase 5
TMEM176A transmembrane protein 176A
TMEM74B transmembrane protein 74B
TMSB4Y thymosin beta 4, Y-linked
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
WASF1 WAS protein family, member 1
WWC2 WW and C2 domain containing 2
ZCCHC2 zinc finger, CCHC domain containing 2
ZFHX3 zinc finger homeobox 3
ZFHX4 zinc finger homeobox 4
ZNRD1-AS1 ZNRD1 antisense RNA 1