| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the raloxifene-3480 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARL4C | ADP-ribosylation factor-like 4C |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BTG2 | BTG family, member 2 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCDC186 | coiled-coil domain containing 186 |
| CCNG2 | cyclin G2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EPOR | erythropoietin receptor |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FSTL1 | follistatin-like 1 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GOSR2 | golgi SNAP receptor complex member 2 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIST1H2BC | histone cluster 1, H2bc |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IFT140 | intraflagellar transport 140 |
| IFT27 | intraflagellar transport 27 |
| INSIG1 | insulin induced gene 1 |
| KLHL24 | kelch-like family member 24 |
| KLHL25 | kelch-like family member 25 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED16 | mediator complex subunit 16 |
| MEFV | Mediterranean fever |
| MPZL2 | myelin protein zero-like 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTRF1L | mitochondrial translational release factor 1-like |
| MVD | mevalonate (diphospho) decarboxylase |
| MVK | mevalonate kinase |
| MXD3 | MAX dimerization protein 3 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRSS16 | protease, serine, 16 (thymus) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RIN2 | Ras and Rab interactor 2 |
| RNF31 | ring finger protein 31 |
| RNF43 | ring finger protein 43 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEC24D | SEC24 family member D |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMIM14 | small integral membrane protein 14 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SQLE | squalene epoxidase |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STON1 | stonin 1 |
| STRA6 | stimulated by retinoic acid 6 |
| STX5 | syntaxin 5 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TESK2 | testis-specific kinase 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| VEGFB | vascular endothelial growth factor B |
| VLDLR | very low density lipoprotein receptor |
| WFDC2 | WAP four-disulfide core domain 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF287 | zinc finger protein 287 |
| ZNF350 | zinc finger protein 350 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5AR2 | complement component 5a receptor 2 |
| CA2 | carbonic anhydrase II |
| CAPN15 | calpain 15 |
| CCDC69 | coiled-coil domain containing 69 |
| CCND1 | cyclin D1 |
| CDK20 | cyclin-dependent kinase 20 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPO | centromere protein O |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DACH1 | dachshund family transcription factor 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EGR3 | early growth response 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM155B | family with sequence similarity 155, member B |
| FAM169A | family with sequence similarity 169, member A |
| FBXO5 | F-box protein 5 |
| FHL2 | four and a half LIM domains 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FMOD | fibromodulin |
| FOXC1 | forkhead box C1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT22 | intraflagellar transport 22 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL17RA | interleukin 17 receptor A |
| IL17RB | interleukin 17 receptor B |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KLK5 | kallikrein-related peptidase 5 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MBTD1 | mbt domain containing 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MITF | microphthalmia-associated transcription factor |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSMB | microseminoprotein, beta- |
| MTCP1 | mature T-cell proliferation 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARD6B | par-6 family cell polarity regulator beta |
| PDZK1 | PDZ domain containing 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLL | polymerase (DNA directed), lambda |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTGES | prostaglandin E synthase |
| RAB3D | RAB3D, member RAS oncogene family |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF170 | ring finger protein 170 |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STC2 | stanniocalcin 2 |
| TARP | TCR gamma alternate reading frame protein |
| TDRD1 | tudor domain containing 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS1 | thrombospondin 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAIP | TRAF interacting protein |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| WDR43 | WD repeat domain 43 |
| WDR76 | WD repeat domain 76 |
| ZNF205 | zinc finger protein 205 |
| ZNF34 | zinc finger protein 34 |
