| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the raloxifene-376 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| APCS | amyloid P component, serum |
| ARMC4 | armadillo repeat containing 4 |
| ARMC7 | armadillo repeat containing 7 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| BCL7C | B-cell CLL/lymphoma 7C |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CCNG2 | cyclin G2 |
| CCPG1 | cell cycle progression 1 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CIAO1 | cytosolic iron-sulfur assembly component 1 |
| CKAP2 | cytoskeleton associated protein 2 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CUL4B | cullin 4B |
| CYFIP1 | cytoplasmic FMR1 interacting protein 1 |
| DUS2 | dihydrouridine synthase 2 |
| DVL3 | dishevelled segment polarity protein 3 |
| DXO | decapping exoribonuclease |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| EFNA1 | ephrin-A1 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EPHA1 | EPH receptor A1 |
| FAM188A | family with sequence similarity 188, member A |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FNBP1L | formin binding protein 1-like |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GLG1 | golgi glycoprotein 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GON4L | gon-4-like (C. elegans) |
| GTPBP2 | GTP binding protein 2 |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLHL28 | kelch-like family member 28 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC23 | leucine rich repeat containing 23 |
| LUZP1 | leucine zipper protein 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MID1 | midline 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MRC2 | mannose receptor, C type 2 |
| NELL2 | NEL-like 2 (chicken) |
| OTUD3 | OTU deubiquitinase 3 |
| PCDH7 | protocadherin 7 |
| PCDHB3 | protocadherin beta 3 |
| PEPD | peptidase D |
| PGRMC2 | progesterone receptor membrane component 2 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PLCD1 | phospholipase C, delta 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| RAB27B | RAB27B, member RAS oncogene family |
| RGS3 | regulator of G-protein signaling 3 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
| SEC23A | Sec23 homolog A (S. cerevisiae) |
| SETD2 | SET domain containing 2 |
| SH2B2 | SH2B adaptor protein 2 |
| SIGMAR1 | sigma non-opioid intracellular receptor 1 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SVIL | supervillin |
| TANK | TRAF family member-associated NFKB activator |
| TESK2 | testis-specific kinase 2 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM53 | transmembrane protein 53 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIM23 | tripartite motif containing 23 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSC22D3 | TSC22 domain family, member 3 |
| TYK2 | tyrosine kinase 2 |
| UBOX5 | U-box domain containing 5 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| WWOX | WW domain containing oxidoreductase |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZMYM4 | zinc finger, MYM-type 4 |
| ZNF43 | zinc finger protein 43 |
| ZNF446 | zinc finger protein 446 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| ARG1 | arginase 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BMP10 | bone morphogenetic protein 10 |
| CAV3 | caveolin 3 |
| CCL16 | chemokine (C-C motif) ligand 16 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CDH17 | cadherin 17, LI cadherin (liver-intestine) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORT | cortistatin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRYAB | crystallin, alpha B |
| CSF1R | colony stimulating factor 1 receptor |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTSE | cathepsin E |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXORF21 | chromosome X open reading frame 21 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DUSP13 | dual specificity phosphatase 13 |
| EGR3 | early growth response 3 |
| EVPL | envoplakin |
| EXOSC9 | exosome component 9 |
| FANCE | Fanconi anemia, complementation group E |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOLR2 | folate receptor 2 (fetal) |
| FOXC1 | forkhead box C1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSTL1 | follistatin-like 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HDAC11 | histone deacetylase 11 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4G | histone cluster 1, H4g |
| HIST1H4J | histone cluster 1, H4j |
| HMP19 | HMP19 protein |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| IL2RG | interleukin 2 receptor, gamma |
| IL6 | interleukin 6 |
| INE1 | inactivation escape 1 (non-protein coding) |
| ITK | IL2-inducible T-cell kinase |
| JAM2 | junctional adhesion molecule 2 |
| KCNJ10 | potassium channel, inwardly rectifying subfamily J, member 10 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 |
| LHX6 | LIM homeobox 6 |
| LMTK1 | lemur tail kinase 1 |
| LOC440895 | two pore channel 3 pseudogene |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MXRA5 | matrix-remodelling associated 5 |
| MYBPC3 | myosin binding protein C, cardiac |
| MYH7 | myosin, heavy chain 7, cardiac muscle, beta |
| MYL5 | myosin, light chain 5, regulatory |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPTX1 | neuronal pentraxin I |
| NUPL1 | nucleoporin like 1 |
| ONECUT2 | one cut homeobox 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PEX26 | peroxisomal biogenesis factor 26 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR14L | proline rich 14-like |
| SCGN | secretagogin, EF-hand calcium binding protein |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPAG11A | sperm associated antigen 11A |
| SPRR3 | small proline-rich protein 3 |
| STAB2 | stabilin 2 |
| SUSD4 | sushi domain containing 4 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TRAC | T cell receptor alpha constant |
| TRAV8-3 | T cell receptor alpha variable 8-3 |
| TTN | titin |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USP29 | ubiquitin specific peptidase 29 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| XYLT2 | xylosyltransferase II |
| ZNF652 | zinc finger protein 652 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZNRF4 | zinc and ring finger 4 |
