| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the raloxifene-6235 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ATM | ATM serine/threonine kinase |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BAX | BCL2-associated X protein |
| BTG2 | BTG family, member 2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CCNO | cyclin O |
| CD8B | CD8b molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHKB | choline kinase beta |
| CORO7 | coronin 7 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTSF | cathepsin F |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DOCK5 | dedicator of cytokinesis 5 |
| ECE1 | endothelin converting enzyme 1 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| FAAH | fatty acid amide hydrolase |
| FAM188A | family with sequence similarity 188, member A |
| FLCN | folliculin |
| FOXN2 | forkhead box N2 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HNF1A | HNF1 homeobox A |
| HOXA6 | homeobox A6 |
| IBSP | integrin-binding sialoprotein |
| IL1R1 | interleukin 1 receptor, type I |
| INSIG1 | insulin induced gene 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JRK | Jrk homolog (mouse) |
| JUND | jun D proto-oncogene |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL24 | kelch-like family member 24 |
| KRT14 | keratin 14, type I |
| KRT19P2 | keratin 19 pseudogene 2 |
| LPIN1 | lipin 1 |
| LRRC14 | leucine rich repeat containing 14 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAP1B | microtubule-associated protein 1B |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MID1 | midline 1 |
| MMP19 | matrix metallopeptidase 19 |
| MPPE1 | metallophosphoesterase 1 |
| MSR1 | macrophage scavenger receptor 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MXD4 | MAX dimerization protein 4 |
| N4BP1 | NEDD4 binding protein 1 |
| NDUFA5 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OTUD3 | OTU deubiquitinase 3 |
| OVOL1 | ovo-like zinc finger 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCGF2 | polycomb group ring finger 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCH1 | phospholipase C, eta 1 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRR4 | proline rich 4 (lacrimal) |
| PTRF | polymerase I and transcript release factor |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF24 | ring finger protein 24 |
| RNF39 | ring finger protein 39 |
| RPS3A | ribosomal protein S3A |
| SAMD4A | sterile alpha motif domain containing 4A |
| SAMD9 | sterile alpha motif domain containing 9 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SIK2 | salt-inducible kinase 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SP100 | SP100 nuclear antigen |
| SPAG8 | sperm associated antigen 8 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYNJ2 | synaptojanin 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIMELESS | timeless circadian clock |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM63A | transmembrane protein 63A |
| TRIM62 | tripartite motif containing 62 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UBE3A | ubiquitin protein ligase E3A |
| UBTD1 | ubiquitin domain containing 1 |
| UBXN1 | UBX domain protein 1 |
| ULBP2 | UL16 binding protein 2 |
| WDR1 | WD repeat domain 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| AXIN1 | axin 1 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CCND1 | cyclin D1 |
| CISH | cytokine inducible SH2-containing protein |
| COCH | cochlin |
| CRCP | CGRP receptor component |
| CTNNBL1 | catenin, beta like 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNM1 | dynamin 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EGR3 | early growth response 3 |
| EVPL | envoplakin |
| EXOC5 | exocyst complex component 5 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOSL1 | FOS-like antigen 1 |
| FPGS | folylpolyglutamate synthase |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF2I | general transcription factor IIi |
| H2AFY2 | H2A histone family, member Y2 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HPSE | heparanase |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL17RB | interleukin 17 receptor B |
| INO80D | INO80 complex subunit D |
| ISG15 | ISG15 ubiquitin-like modifier |
| KIAA0020 | KIAA0020 |
| KLF10 | Kruppel-like factor 10 |
| KLHL21 | kelch-like family member 21 |
| KRT13 | keratin 13, type I |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MANEA | mannosidase, endo-alpha |
| MED9 | mediator complex subunit 9 |
| METTL1 | methyltransferase like 1 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MREG | melanoregulin |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MXD3 | MAX dimerization protein 3 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDZK1 | PDZ domain containing 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PRR7 | proline rich 7 (synaptic) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RECQL4 | RecQ protein-like 4 |
| REEP4 | receptor accessory protein 4 |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| RPIA | ribose 5-phosphate isomerase A |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SAV1 | salvador family WW domain containing protein 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SMYD5 | SMYD family member 5 |
| STC2 | stanniocalcin 2 |
| SULF1 | sulfatase 1 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN1 | tectonic family member 1 |
| TGDS | TDP-glucose 4,6-dehydratase |
| TMC7 | transmembrane channel-like 7 |
| TMEM164 | transmembrane protein 164 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| UBXN6 | UBX domain protein 6 |
| XYLT2 | xylosyltransferase II |
| ZNF276 | zinc finger protein 276 |
| ZNF586 | zinc finger protein 586 |
| ZNF668 | zinc finger protein 668 |
| ZNF787 | zinc finger protein 787 |
| ZNF816 | zinc finger protein 816 |
| ZNF83 | zinc finger protein 83 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
