Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the ramifenazone-7233 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACSF2 | acyl-CoA synthetase family member 2 |
ACTN2 | actinin, alpha 2 |
ADAM8 | ADAM metallopeptidase domain 8 |
AKR1C2 | aldo-keto reductase family 1, member C2 |
APLP2 | amyloid beta (A4) precursor-like protein 2 |
AQP3 | aquaporin 3 (Gill blood group) |
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
ATAT1 | alpha tubulin acetyltransferase 1 |
C17ORF59 | chromosome 17 open reading frame 59 |
C8ORF60 | chromosome 8 open reading frame 60 |
CASP10 | caspase 10, apoptosis-related cysteine peptidase |
CD82 | CD82 molecule |
CDRT1 | CMT1A duplicated region transcript 1 |
CLCA2 | chloride channel accessory 2 |
CNOT3 | CCR4-NOT transcription complex, subunit 3 |
CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
DLK2 | delta-like 2 homolog (Drosophila) |
DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
ELL2 | elongation factor, RNA polymerase II, 2 |
ELOVL5 | ELOVL fatty acid elongase 5 |
ELP6 | elongator acetyltransferase complex subunit 6 |
EML3 | echinoderm microtubule associated protein like 3 |
ESR1 | estrogen receptor 1 |
FAM13C | family with sequence similarity 13, member C |
FAM186A | family with sequence similarity 186, member A |
FKBP10 | FK506 binding protein 10, 65 kDa |
FUT7 | fucosyltransferase 7 (alpha (1,3) fucosyltransferase) |
GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
GJA9 | gap junction protein, alpha 9, 59kDa |
GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
GSK3A | glycogen synthase kinase 3 alpha |
HBS1L | HBS1-like translational GTPase |
HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
HNF1A | HNF1 homeobox A |
IGFBP5 | insulin-like growth factor binding protein 5 |
IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
INCENP | inner centromere protein antigens 135/155kDa |
INTS1 | integrator complex subunit 1 |
ITGB6 | integrin, beta 6 |
JAM3 | junctional adhesion molecule 3 |
KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
KIAA0368 | KIAA0368 |
LAT2 | linker for activation of T cells family, member 2 |
LEPR | leptin receptor |
LRRC6 | leucine rich repeat containing 6 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
MAN2A2 | mannosidase, alpha, class 2A, member 2 |
MINK1 | misshapen-like kinase 1 |
MMP25 | matrix metallopeptidase 25 |
MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
MYLK | myosin light chain kinase |
NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
OTUD4 | OTU deubiquitinase 4 |
PCSK6 | proprotein convertase subtilisin/kexin type 6 |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide |
PEX5 | peroxisomal biogenesis factor 5 |
PLLP | plasmolipin |
PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
PSD4 | pleckstrin and Sec7 domain containing 4 |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PXDC1 | PX domain containing 1 |
RAB3B | RAB3B, member RAS oncogene family |
RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
RPL18 | ribosomal protein L18 |
RUFY3 | RUN and FYVE domain containing 3 |
S100A9 | S100 calcium binding protein A9 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SERHL2 | serine hydrolase-like 2 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
SLIT2 | slit homolog 2 (Drosophila) |
SOX9 | SRY (sex determining region Y)-box 9 |
SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
SSX1 | synovial sarcoma, X breakpoint 1 |
SYCP1 | synaptonemal complex protein 1 |
TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
TAOK1 | TAO kinase 1 |
TDRKH | tudor and KH domain containing |
TM4SF1 | transmembrane 4 L six family member 1 |
TMEM120B | transmembrane protein 120B |
TMEM19 | transmembrane protein 19 |
TMPRSS2 | transmembrane protease, serine 2 |
TOP3A | topoisomerase (DNA) III alpha |
TPK1 | thiamin pyrophosphokinase 1 |
TPP1 | tripeptidyl peptidase I |
TSPAN1 | tetraspanin 1 |
UBA6 | ubiquitin-like modifier activating enzyme 6 |
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
WDR55 | WD repeat domain 55 |
ZBTB33 | zinc finger and BTB domain containing 33 |
ZER1 | zyg-11 related, cell cycle regulator |
ZNF41 | zinc finger protein 41 |
Symbol | Name |
---|---|
ANXA2P3 | annexin A2 pseudogene 3 |
ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
BRAF | B-Raf proto-oncogene, serine/threonine kinase |
C22ORF29 | chromosome 22 open reading frame 29 |
CCDC25 | coiled-coil domain containing 25 |
CD302 | CD302 molecule |
CDON | cell adhesion associated, oncogene regulated |
CGREF1 | cell growth regulator with EF-hand domain 1 |
CIC | capicua transcriptional repressor |
CISH | cytokine inducible SH2-containing protein |
CLEC16A | C-type lectin domain family 16, member A |
CLSPN | claspin |
CPOX | coproporphyrinogen oxidase |
CRYBG3 | beta-gamma crystallin domain containing 3 |
CTSK | cathepsin K |
DSCAM | Down syndrome cell adhesion molecule |
DUSP2 | dual specificity phosphatase 2 |
DUSP8 | dual specificity phosphatase 8 |
DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
EXD3 | exonuclease 3'-5' domain containing 3 |
F3 | coagulation factor III (thromboplastin, tissue factor) |
FAM155B | family with sequence similarity 155, member B |
FAM169A | family with sequence similarity 169, member A |
FBXO2 | F-box protein 2 |
FLCN | folliculin |
FZD4 | frizzled class receptor 4 |
GALK1 | galactokinase 1 |
GAREM | GRB2 associated, regulator of MAPK1 |
GID4 | GID complex subunit 4 |
GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
GPATCH2L | G patch domain containing 2-like |
GPX2 | glutathione peroxidase 2 |
GRB7 | growth factor receptor-bound protein 7 |
GUSBP3 | glucuronidase, beta pseudogene 3 |
H2AFJ | H2A histone family, member J |
IFNA14 | interferon, alpha 14 |
IL15RA | interleukin 15 receptor, alpha |
IPO8 | importin 8 |
IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
IRF6 | interferon regulatory factor 6 |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
LNPEP | leucyl/cystinyl aminopeptidase |
MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
MAST3 | microtubule associated serine/threonine kinase 3 |
MBTD1 | mbt domain containing 1 |
MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
MTMR11 | myotubularin related protein 11 |
NUP62CL | nucleoporin 62kDa C-terminal like |
OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
PACS1 | phosphofurin acidic cluster sorting protein 1 |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PGP | phosphoglycolate phosphatase |
PGPEP1 | pyroglutamyl-peptidase I |
PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
QTRT1 | queuine tRNA-ribosyltransferase 1 |
R3HCC1L | R3H domain and coiled-coil containing 1-like |
RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
RIBC2 | RIB43A domain with coiled-coils 2 |
RNF2 | ring finger protein 2 |
ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
RPL23AP32 | ribosomal protein L23a pseudogene 32 |
RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SH2D4A | SH2 domain containing 4A |
SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
SMA4 | glucuronidase, beta pseudogene |
SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
SPIDR | scaffolding protein involved in DNA repair |
SPRYD7 | SPRY domain containing 7 |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
SYCP2 | synaptonemal complex protein 2 |
TBX19 | T-box 19 |
TCTN1 | tectonic family member 1 |
TDRD1 | tudor domain containing 1 |
TESK1 | testis-specific kinase 1 |
THBS3 | thrombospondin 3 |
TRAF2 | TNF receptor-associated factor 2 |
TRIM5 | tripartite motif containing 5 |
TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
WDR4 | WD repeat domain 4 |
WDR62 | WD repeat domain 62 |
WLS | wntless Wnt ligand secretion mediator |
ZBED1 | zinc finger, BED-type containing 1 |
ZFYVE16 | zinc finger, FYVE domain containing 16 |
ZMAT5 | zinc finger, matrin-type 5 |
ZNF141 | zinc finger protein 141 |
ZNF212 | zinc finger protein 212 |
ZNF492 | zinc finger protein 492 |
ZNF675 | zinc finger protein 675 |