ramifenazone Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

24 genes differentially expressed following the ramifenazone small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SYNGR3 synaptogyrin 3 4.82368
ZNF586 zinc finger protein 586 4.61211
YME1L1 YME1-like 1 ATPase 3.96998
XIC X chromosome inactivation center 3.92159
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 3.83327
ZNF134 zinc finger protein 134 3.79145
STXBP1 syntaxin binding protein 1 3.72835
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.47049
ACSM3 acyl-CoA synthetase medium-chain family member 3 3.46992
CNTNAP2 contactin associated protein-like 2 3.39431
POLG2 polymerase (DNA directed), gamma 2, accessory subunit 3.30965
MOG myelin oligodendrocyte glycoprotein 3.21456
CCDC88A coiled-coil domain containing 88A 3.08752
GTPBP4 GTP binding protein 4 3.05121

decreased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 -4.65634
ZDHHC6 zinc finger, DHHC-type containing 6 -4.38639
EGR1 early growth response 1 -3.48073
CLDN15 claudin 15 -3.43255
BID BH3 interacting domain death agonist -3.23337
GLI2 GLI family zinc finger 2 -3.17706
KANSL3 KAT8 regulatory NSL complex subunit 3 -3.15249
ETFB electron-transfer-flavoprotein, beta polypeptide -3.12253
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -3.08238
GAB1 GRB2-associated binding protein 1 -3.01776