| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the ramipril-7144 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKAP10 | A kinase (PRKA) anchor protein 10 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| AXIN1 | axin 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BRAP | BRCA1 associated protein |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDON | cell adhesion associated, oncogene regulated |
| CLDN15 | claudin 15 |
| CPNE7 | copine VII |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DESI2 | desumoylating isopeptidase 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EFNA5 | ephrin-A5 |
| ETV1 | ets variant 1 |
| FAM105A | family with sequence similarity 105, member A |
| FAT4 | FAT atypical cadherin 4 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GRK6 | G protein-coupled receptor kinase 6 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| H2AFX | H2A histone family, member X |
| HES2 | hes family bHLH transcription factor 2 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HOXA4 | homeobox A4 |
| IFT74 | intraflagellar transport 74 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL1RAP | interleukin 1 receptor accessory protein |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGA10 | integrin, alpha 10 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITGB4 | integrin, beta 4 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT34 | keratin 34, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LMNB1 | lamin B1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAPK12 | mitogen-activated protein kinase 12 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MXD4 | MAX dimerization protein 4 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NF2 | neurofibromin 2 (merlin) |
| NKX3-2 | NK3 homeobox 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PEX5 | peroxisomal biogenesis factor 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| RAB2A | RAB2A, member RAS oncogene family |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RANBP3 | RAN binding protein 3 |
| RNF122 | ring finger protein 122 |
| RUNX1 | runt-related transcription factor 1 |
| SAFB2 | scaffold attachment factor B2 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPPL2B | signal peptide peptidase like 2B |
| STXBP6 | syntaxin binding protein 6 (amisyn) |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TBC1D22A | TBC1 domain family, member 22A |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMF1 | TATA element modulatory factor 1 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TPP1 | tripeptidyl peptidase I |
| TSSK2 | testis-specific serine kinase 2 |
| TTC12 | tetratricopeptide repeat domain 12 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UGT8 | UDP glycosyltransferase 8 |
| USP20 | ubiquitin specific peptidase 20 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| VWA8 | von Willebrand factor A domain containing 8 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFHX3 | zinc finger homeobox 3 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZMYM5 | zinc finger, MYM-type 5 |
| ZNF222 | zinc finger protein 222 |
| ZNF43 | zinc finger protein 43 |
| ZNF589 | zinc finger protein 589 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAK1 | BCL2-antagonist/killer 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCS | copper chaperone for superoxide dismutase |
| CDC37L1 | cell division cycle 37-like 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| COG4 | component of oligomeric golgi complex 4 |
| CPOX | coproporphyrinogen oxidase |
| CUL9 | cullin 9 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNM1 | dynamin 1 |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| EPHB6 | EPH receptor B6 |
| ERCC2 | excision repair cross-complementation group 2 |
| FAM155A | family with sequence similarity 155, member A |
| GLCE | glucuronic acid epimerase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPATCH1 | G patch domain containing 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IFT22 | intraflagellar transport 22 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ISL1 | ISL LIM homeobox 1 |
| KLC2 | kinesin light chain 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| METTL2B | methyltransferase like 2B |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDRG4 | NDRG family member 4 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLD2 | phospholipase D2 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RAB3A | RAB3A, member RAS oncogene family |
| RBM38 | RNA binding motif protein 38 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFWD3 | ring finger and WD repeat domain 3 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SDF2 | stromal cell-derived factor 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD1B | SET domain containing 1B |
| SETD6 | SET domain containing 6 |
| SHPK | sedoheptulokinase |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNX15 | sorting nexin 15 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TEAD3 | TEA domain family member 3 |
| TGS1 | trimethylguanosine synthase 1 |
| THAP10 | THAP domain containing 10 |
| THBS3 | thrombospondin 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM242 | transmembrane protein 242 |
| TMEM51 | transmembrane protein 51 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTF2 | transcription termination factor, RNA polymerase II |
| UNC13B | unc-13 homolog B (C. elegans) |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WDR37 | WD repeat domain 37 |
| ZBTB5 | zinc finger and BTB domain containing 5 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF32 | zinc finger protein 32 |
| ZNF552 | zinc finger protein 552 |
| ZNF84 | zinc finger protein 84 |
