ramipril-7144 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the ramipril-7144 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP10 A kinase (PRKA) anchor protein 10
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AXIN1 axin 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BRAP BRCA1 associated protein
C7ORF43 chromosome 7 open reading frame 43
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDON cell adhesion associated, oncogene regulated
CLDN15 claudin 15
CPNE7 copine VII
CTNND2 catenin (cadherin-associated protein), delta 2
CYHR1 cysteine/histidine-rich 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DESI2 desumoylating isopeptidase 2
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
EFCAB2 EF-hand calcium binding domain 2
EFNA5 ephrin-A5
ETV1 ets variant 1
FAM105A family with sequence similarity 105, member A
FAT4 FAT atypical cadherin 4
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GRK6 G protein-coupled receptor kinase 6
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
H2AFX H2A histone family, member X
HES2 hes family bHLH transcription factor 2
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HOXA4 homeobox A4
IFT74 intraflagellar transport 74
IGSF3 immunoglobulin superfamily, member 3
IL1RAP interleukin 1 receptor accessory protein
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITGA10 integrin, alpha 10
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
KMT2A lysine (K)-specific methyltransferase 2A
KRT34 keratin 34, type I
LAT2 linker for activation of T cells family, member 2
LMNB1 lamin B1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAGOH2P mago-nashi homolog 2, pseudogene
MAPK12 mitogen-activated protein kinase 12
MFGE8 milk fat globule-EGF factor 8 protein
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MXD4 MAX dimerization protein 4
NCKIPSD NCK interacting protein with SH3 domain
NF2 neurofibromin 2 (merlin)
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPM3 nucleophosmin/nucleoplasmin 3
NUP62CL nucleoporin 62kDa C-terminal like
OASL 2'-5'-oligoadenylate synthetase-like
PDLIM2 PDZ and LIM domain 2 (mystique)
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX5 peroxisomal biogenesis factor 5
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
RAB2A RAB2A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RANBP3 RAN binding protein 3
RNF122 ring finger protein 122
RUNX1 runt-related transcription factor 1
SAFB2 scaffold attachment factor B2
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SIAH1 siah E3 ubiquitin protein ligase 1
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SMG7 SMG7 nonsense mediated mRNA decay factor
SNHG3 small nucleolar RNA host gene 3
SPPL2B signal peptide peptidase like 2B
STXBP6 syntaxin binding protein 6 (amisyn)
SUN1 Sad1 and UNC84 domain containing 1
TBC1D22A TBC1 domain family, member 22A
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMF1 TATA element modulatory factor 1
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPP1 tripeptidyl peptidase I
TSSK2 testis-specific serine kinase 2
TTC12 tetratricopeptide repeat domain 12
TTC38 tetratricopeptide repeat domain 38
UGT8 UDP glycosyltransferase 8
USP20 ubiquitin specific peptidase 20
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
VWA8 von Willebrand factor A domain containing 8
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX3 zinc finger homeobox 3
ZFYVE9 zinc finger, FYVE domain containing 9
ZMYM5 zinc finger, MYM-type 5
ZNF222 zinc finger protein 222
ZNF43 zinc finger protein 43
ZNF589 zinc finger protein 589
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTN4 actinin, alpha 4
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ASTE1 asteroid homolog 1 (Drosophila)
ATAD2B ATPase family, AAA domain containing 2B
BAK1 BCL2-antagonist/killer 1
C16ORF59 chromosome 16 open reading frame 59
C1ORF159 chromosome 1 open reading frame 159
C9ORF91 chromosome 9 open reading frame 91
CALCOCO1 calcium binding and coiled-coil domain 1
CBY1 chibby homolog 1 (Drosophila)
CCS copper chaperone for superoxide dismutase
CDC37L1 cell division cycle 37-like 1
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COG4 component of oligomeric golgi complex 4
CPOX coproporphyrinogen oxidase
CUL9 cullin 9
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DLK2 delta-like 2 homolog (Drosophila)
DNM1 dynamin 1
DPY19L2P2 DPY19L2 pseudogene 2
EPHB6 EPH receptor B6
ERCC2 excision repair cross-complementation group 2
FAM155A family with sequence similarity 155, member A
GLCE glucuronic acid epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH1 G patch domain containing 1
GRWD1 glutamate-rich WD repeat containing 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IFT22 intraflagellar transport 22
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
ISL1 ISL LIM homeobox 1
KLC2 kinesin light chain 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK3 mitogen-activated protein kinase 3
METTL2B methyltransferase like 2B
MPDU1 mannose-P-dolichol utilization defect 1
MRPL44 mitochondrial ribosomal protein L44
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MTG1 mitochondrial ribosome-associated GTPase 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NDRG4 NDRG family member 4
NT5C 5', 3'-nucleotidase, cytosolic
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PID1 phosphotyrosine interaction domain containing 1
PLD2 phospholipase D2
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB3A RAB3A, member RAS oncogene family
RBM38 RNA binding motif protein 38
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFWD3 ring finger and WD repeat domain 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RPP25 ribonuclease P/MRP 25kDa subunit
RPUSD2 RNA pseudouridylate synthase domain containing 2
SDF2 stromal cell-derived factor 2
SERTAD3 SERTA domain containing 3
SETD1B SET domain containing 1B
SETD6 SET domain containing 6
SHPK sedoheptulokinase
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX15 sorting nexin 15
SOX12 SRY (sex determining region Y)-box 12
STARD13 StAR-related lipid transfer (START) domain containing 13
TEAD3 TEA domain family member 3
TGS1 trimethylguanosine synthase 1
THAP10 THAP domain containing 10
THBS3 thrombospondin 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TMEM242 transmembrane protein 242
TMEM51 transmembrane protein 51
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC23 tetratricopeptide repeat domain 23
TTC33 tetratricopeptide repeat domain 33
TTC4 tetratricopeptide repeat domain 4
TTF2 transcription termination factor, RNA polymerase II
UNC13B unc-13 homolog B (C. elegans)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
WDR37 WD repeat domain 37
ZBTB5 zinc finger and BTB domain containing 5
ZHX2 zinc fingers and homeoboxes 2
ZNF32 zinc finger protein 32
ZNF552 zinc finger protein 552
ZNF84 zinc finger protein 84