ranitidine-5425 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the ranitidine-5425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADGB androglobin
AIF1 allograft inflammatory factor 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
AMOT angiomotin
ANKRD34C ankyrin repeat domain 34C
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
C1ORF54 chromosome 1 open reading frame 54
CCR7 chemokine (C-C motif) receptor 7
CD1A CD1a molecule
CDK6 cyclin-dependent kinase 6
CLTB clathrin, light chain B
COL1A1 collagen, type I, alpha 1
CTIF CBP80/20-dependent translation initiation factor
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3
DMPK dystrophia myotonica-protein kinase
EMID1 EMI domain containing 1
EXT1 exostosin glycosyltransferase 1
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FMO5 flavin containing monooxygenase 5
FOXG1 forkhead box G1
FPR1 formyl peptide receptor 1
FRS3 fibroblast growth factor receptor substrate 3
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GHRHR growth hormone releasing hormone receptor
GJA4 gap junction protein, alpha 4, 37kDa
GPX5 glutathione peroxidase 5
HSF4 heat shock transcription factor 4
IL11 interleukin 11
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KHSRP KH-type splicing regulatory protein
KIF13B kinesin family member 13B
KLF1 Kruppel-like factor 1 (erythroid)
LMF2 lipase maturation factor 2
LPAR4 lysophosphatidic acid receptor 4
LRP2 low density lipoprotein receptor-related protein 2
MAPK7 mitogen-activated protein kinase 7
MATN1 matrilin 1, cartilage matrix protein
MFAP5 microfibrillar associated protein 5
MFSD6 major facilitator superfamily domain containing 6
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NKX2-5 NK2 homeobox 5
NPY2R neuropeptide Y receptor Y2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OPRK1 opioid receptor, kappa 1
OR1E1 olfactory receptor, family 1, subfamily E, member 1
PARVA parvin, alpha
PDE4A phosphodiesterase 4A, cAMP-specific
PDZD7 PDZ domain containing 7
PIDD1 p53-induced death domain protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PITX1 paired-like homeodomain 1
PLA2G10 phospholipase A2, group X
PLSCR4 phospholipid scramblase 4
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
RARA retinoic acid receptor, alpha
RBM12B RNA binding motif protein 12B
RGS14 regulator of G-protein signaling 14
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RTEL1 regulator of telomere elongation helicase 1
SARM1 sterile alpha and TIR motif containing 1
SCAI suppressor of cancer cell invasion
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SHANK1 SH3 and multiple ankyrin repeat domains 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
TBCD tubulin folding cofactor D
TCF12 transcription factor 12
TECPR2 tectonin beta-propeller repeat containing 2
TEX14 testis expressed 14
TGM2 transglutaminase 2
TJAP1 tight junction associated protein 1 (peripheral)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TTLL5 tubulin tyrosine ligase-like family member 5
VGLL3 vestigial-like family member 3
ZNF280A zinc finger protein 280A
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD17B abhydrolase domain containing 17B
ACBD4 acyl-CoA binding domain containing 4
ADCY7 adenylate cyclase 7
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARRB1 arrestin, beta 1
ATF3 activating transcription factor 3
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B9D2 B9 protein domain 2
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
C5AR2 complement component 5a receptor 2
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC186 coiled-coil domain containing 186
CD82 CD82 molecule
CEP97 centrosomal protein 97kDa
CLCF1 cardiotrophin-like cytokine factor 1
CLDN15 claudin 15
CLSPN claspin
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
DBF4B DBF4 zinc finger B
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPHX2 epoxide hydrolase 2, cytoplasmic
FAM212B family with sequence similarity 212, member B
FGL1 fibrinogen-like 1
FOLR1 folate receptor 1 (adult)
GLRA1 glycine receptor, alpha 1
GMPR guanosine monophosphate reductase
GRB7 growth factor receptor-bound protein 7
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
IDI2-AS1 IDI2 antisense RNA 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM5C lysine (K)-specific demethylase 5C
KPNA5 karyopherin alpha 5 (importin alpha 6)
LOC100286895 cell division cycle 27 homolog pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MEFV Mediterranean fever
MOCS3 molybdenum cofactor synthesis 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MRPS18C mitochondrial ribosomal protein S18C
NDE1 nudE neurodevelopment protein 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5C 5', 3'-nucleotidase, cytosolic
OXTR oxytocin receptor
PARD6B par-6 family cell polarity regulator beta
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
POLH polymerase (DNA directed), eta
PRKCE protein kinase C, epsilon
PRR4 proline rich 4 (lacrimal)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAB30 RAB30, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RPGRIP1L RPGRIP1-like
S100A4 S100 calcium binding protein A4
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIRAL2 SIR2 antiphage like 2
SIX1 SIX homeobox 1
SKI SKI proto-oncogene
SLC12A9 solute carrier family 12, member 9
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SPRYD7 SPRY domain containing 7
SRBD1 S1 RNA binding domain 1
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
STRA6 stimulated by retinoic acid 6
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCTN1 tectonic family member 1
TET3 tet methylcytosine dioxygenase 3
TGFBI transforming growth factor, beta-induced, 68kDa
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAIP TRAF interacting protein
TRIM36 tripartite motif containing 36
TRIM5 tripartite motif containing 5
TUBG2 tubulin, gamma 2
VEGFC vascular endothelial growth factor C
ZBTB6 zinc finger and BTB domain containing 6
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF480 zinc finger protein 480
ZNF701 zinc finger protein 701