rbpj Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description recombination signal binding protein for immunoglobulin kappa J region|The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2013] (NCBI Entrez Gene Database, 3516)
Similar Terms
Downloads & Tools

Genes

11 genes co-occuring with the biological term rbpj in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BCL2A1 BCL2-related protein A1
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung)
JAG1 jagged 1
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NOTCH1 notch 1
PTF1A pancreas specific transcription factor, 1a
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like
RUNX3 runt-related transcription factor 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)