receptor ligand activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
External Link http://amigo.geneontology.org/amigo/term/GO:0048018
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Genes

381 genes performing the receptor ligand activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ADA2 adenosine deaminase 2
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADM2 adrenomedullin 2
AGXT alanine-glyoxylate aminotransferase
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ALKAL1 ALK and LTK ligand 1
ALKAL2 ALK and LTK ligand 2
AMBN ameloblastin (enamel matrix protein)
AMELX amelogenin, X-linked
AMH anti-Mullerian hormone
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANGPTL3 angiopoietin-like 3
APELA apelin receptor early endogenous ligand
APLN apelin
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ARTN artemin
BAG6 BCL2-associated athanogene 6
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP10 bone morphogenetic protein 10
BMP15 bone morphogenetic protein 15
BMP2 bone morphogenetic protein 2
BMP3 bone morphogenetic protein 3
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BMP8A bone morphogenetic protein 8a
BMP8B bone morphogenetic protein 8b
BTC betacellulin
C1QTNF12 C1q and TNF related 12
C3 complement component 3
CALCA calcitonin-related polypeptide alpha
CALCB calcitonin-related polypeptide beta
CCL11 chemokine (C-C motif) ligand 11
CCL15 chemokine (C-C motif) ligand 15
CCL16 chemokine (C-C motif) ligand 16
CCL2 chemokine (C-C motif) ligand 2
CCL24 chemokine (C-C motif) ligand 24
CCL25 chemokine (C-C motif) ligand 25
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCM2 cerebral cavernous malformation 2
CCN3 cellular communication network factor 3
CD274 CD274 molecule
CD40LG CD40 ligand
CD48 CD48 molecule
CD70 CD70 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CER1 cerberus 1, DAN family BMP antagonist
CERS1 ceramide synthase 1
CGB1 chorionic gonadotropin, beta polypeptide 1
CGB2 chorionic gonadotropin, beta polypeptide 2
CHGA chromogranin A
CHGB chromogranin B
CHLSN cholesin
CLCF1 cardiotrophin-like cytokine factor 1
CLEC11A C-type lectin domain family 11, member A
CLEC1B C-type lectin domain family 1, member B
CLU clusterin
CNTF ciliary neurotrophic factor
COLEC10 collectin sub-family member 10 (C-type lectin)
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRH corticotropin releasing hormone
CRIPTO3 cripto, EGF-CFC family member 3
CRLF1 cytokine receptor-like factor 1
CSF1 colony stimulating factor 1 (macrophage)
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSH2 chorionic somatomammotropin hormone 2
CSHL1 chorionic somatomammotropin hormone-like 1
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C)
CTF1 cardiotrophin 1
CTSG cathepsin G
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
DAND5 DAN domain family member 5, BMP antagonist
DEFB103A defensin, beta 103A
DEFB104A defensin, beta 104A
DEFB109B defensin beta 109B
DEFB110 defensin, beta 110
DEFB114 defensin, beta 114
DEFB130A defensin beta 130A
DEFB130B defensin beta 130B
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLL1 delta-like 1 (Drosophila)
DLL4 delta-like 4 (Drosophila)
DPP4 dipeptidyl-peptidase 4
EDA ectodysplasin A
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EGF epidermal growth factor
ENDOU endonuclease, polyU-specific
EPGN epithelial mitogen
EPHA7 EPH receptor A7
EPX eosinophil peroxidase
EREG epiregulin
ERFE erythroferrone
FAM3B family with sequence similarity 3, member B
FAM3C family with sequence similarity 3, member C
FAM3D family with sequence similarity 3, member D
FASLG Fas ligand (TNF superfamily, member 6)
FBN1 fibrillin 1
FBN2 fibrillin 2
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF13 fibroblast growth factor 13
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF20 fibroblast growth factor 20
FGF21 fibroblast growth factor 21
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
GAS6 growth arrest-specific 6
GAST gastrin
GCG glucagon
GDF10 growth differentiation factor 10
GDF11 growth differentiation factor 11
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF3 growth differentiation factor 3
GDF5 growth differentiation factor 5
GDF6 growth differentiation factor 6
GDF7 growth differentiation factor 7
GDF9 growth differentiation factor 9
GDNF glial cell derived neurotrophic factor
GH1 growth hormone 1
GH2 growth hormone 2
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GPNMB glycoprotein (transmembrane) nmb
GPR15LG G protein-coupled receptor 15 ligand
GREM1 gremlin 1, DAN family BMP antagonist
GREM2 gremlin 2, DAN family BMP antagonist
GRN granulin
GUCA2A guanylate cyclase activator 2A (guanylin)
HAMP hepcidin antimicrobial peptide
HBEGF heparin-binding EGF-like growth factor
HLA-E major histocompatibility complex, class I, E
HMGB1 high mobility group box 1
HMGB2 high mobility group box 2
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
IAPP islet amyloid polypeptide
ICOSLG inducible T-cell co-stimulator ligand
IFNA1 interferon, alpha 1
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA2 interferon, alpha 2
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNG interferon, gamma
IFNK interferon, kappa
IFNL4 interferon, lambda 4 (gene/pseudogene)
IFNW1 interferon, omega 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL11 interleukin 11
IL12A interleukin 12A
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL16 interleukin 16
IL17D interleukin 17D
IL17F interleukin 17F
IL18 interleukin 18
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1F10 interleukin 1 family, member 10 (theta)
IL2 interleukin 2
IL20 interleukin 20
IL22 interleukin 22
IL24 interleukin 24
IL26 interleukin 26
IL3 interleukin 3
IL31 interleukin 31
IL33 interleukin 33
IL36A interleukin 36, alpha
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL37 interleukin 37
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL7 interleukin 7
IL9 interleukin 9
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INHBC inhibin, beta C
INHBE inhibin, beta E
INS insulin
INSL6 insulin-like 6
ITPRIPL1 inositol 1,4,5-trisphosphate receptor interacting protein-like 1
IZUMO1 izumo sperm-egg fusion 1
JAG1 jagged 1
JAG2 jagged 2
KITLG KIT ligand
KNG1 kininogen 1
LACRT lacritin
LAMA5 laminin, alpha 5
LEFTY1 left-right determination factor 1
LEFTY2 left-right determination factor 2
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS9 lectin, galactoside-binding, soluble, 9
LIF leukemia inhibitory factor
LINC02762 long intergenic non-protein coding RNA 2762
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
MDK midkine (neurite growth-promoting factor 2)
METRN meteorin, glial cell differentiation regulator
METRNL meteorin, glial cell differentiation regulator-like
MICA MHC class I polypeptide-related sequence A
MMRN2 multimerin 2
MSTN myostatin
NCR3LG1 natural killer cell cytotoxicity receptor 3 ligand 1
NDP Norrie disease (pseudoglioma)
NECTIN2 nectin cell adhesion molecule 2
NECTIN4 nectin cell adhesion molecule 4
NGF nerve growth factor (beta polypeptide)
NODAL nodal growth differentiation factor
NPFF neuropeptide FF-amide peptide precursor
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPVF neuropeptide VF precursor
NRG1 neuregulin 1
NRG3 neuregulin 3
NRG4 neuregulin 4
NRTN neurturin
NTF3 neurotrophin 3
NTF4 neurotrophin 4
NTS neurotensin
NXNL1 nucleoredoxin-like 1
OSGIN1 oxidative stress induced growth inhibitor 1
OSGIN2 oxidative stress induced growth inhibitor family member 2
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PENK proenkephalin
PF4 platelet factor 4
PGF placental growth factor
PGLYRP1 peptidoglycan recognition protein 1
POMC proopiomelanocortin
PPY pancreatic polypeptide
PRL prolactin
PRLH prolactin releasing hormone
PSPN persephin
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
PTRH2 peptidyl-tRNA hydrolase 2
PVR poliovirus receptor
PYY peptide YY
REG1A regenerating islet-derived 1 alpha
REG3A regenerating islet-derived 3 alpha
RELN reelin
RIPK2 receptor-interacting serine-threonine kinase 2
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SCG2 secretogranin II
SCGB3A1 secretoglobin, family 3A, member 1
SCT secretin
SECTM1 secreted and transmembrane 1
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SFRP2 secreted frizzled-related protein 2
SHH sonic hedgehog
SLURP1 secreted LY6/PLAUR domain containing 1
SOS1 son of sevenless homolog 1 (Drosophila)
SST somatostatin
TAC1 tachykinin, precursor 1
TAC4 tachykinin 4 (hemokinin)
TAFA1 TAFA chemokine like family member 1
TAFA2 TAFA chemokine like family member 2
TAFA3 TAFA chemokine like family member 3
TAFA4 TAFA chemokine like family member 4
TAFA5 TAFA chemokine like family member 5
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THPO thrombopoietin
TIMP1 TIMP metallopeptidase inhibitor 1
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TOR2A torsin family 2, member A
TSLP thymic stromal lymphopoietin
TTF2 transcription termination factor, RNA polymerase II
ULBP1 UL16 binding protein 1
ULBP2 UL16 binding protein 2
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VEGFC vascular endothelial growth factor C
VEGFD vascular endothelial growth factor D
VGF VGF nerve growth factor inducible
WNT1 wingless-type MMTV integration site family, member 1
WNT10A wingless-type MMTV integration site family, member 10A
WNT10B wingless-type MMTV integration site family, member 10B
WNT11 wingless-type MMTV integration site family, member 11
WNT16 wingless-type MMTV integration site family, member 16
WNT2 wingless-type MMTV integration site family member 2
WNT2B wingless-type MMTV integration site family, member 2B
WNT3 wingless-type MMTV integration site family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
WNT5B wingless-type MMTV integration site family, member 5B
WNT6 wingless-type MMTV integration site family, member 6
WNT7A wingless-type MMTV integration site family, member 7A
WNT7B wingless-type MMTV integration site family, member 7B
WNT8A wingless-type MMTV integration site family, member 8A
WNT8B wingless-type MMTV integration site family, member 8B
WNT9A wingless-type MMTV integration site family, member 9A
WNT9B wingless-type MMTV integration site family, member 9B
ZP3 zona pellucida glycoprotein 3 (sperm receptor)