receptor-mediated endocytosis Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles. (Gene Ontology, GO_0006898)
External Link http://amigo.geneontology.org/amigo/term/GO:0006898
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Genes

183 genes participating in the receptor-mediated endocytosis biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
ACHE acetylcholinesterase (Yt blood group)
ACKR2 atypical chemokine receptor 2
ACKR3 atypical chemokine receptor 3
ACKR4 atypical chemokine receptor 4
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
ALB albumin
AMBP alpha-1-microglobulin/bikunin precursor
AMN amnion associated transmembrane protein
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOBR apolipoprotein B receptor
APOE apolipoprotein E
APOL1 apolipoprotein L, 1
ARHGAP27 Rho GTPase activating protein 27
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ASGR1 asialoglycoprotein receptor 1
ASGR2 asialoglycoprotein receptor 2
CALCR calcitonin receptor
CALCRL calcitonin receptor-like
CALR calreticulin
CANX calnexin
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CD163 CD163 molecule
CD163L1 CD163 molecule-like 1
CD36 CD36 molecule (thrombospondin receptor)
CD5 CD5 molecule
CD5L CD5 molecule-like
CD6 CD6 molecule
CETP cholesteryl ester transfer protein, plasma
CFI complement factor I
CLEC9A C-type lectin domain family 9, member A
CLN3 ceroid-lipofuscinosis, neuronal 3
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CNTN2 contactin 2 (axonal)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
COLEC11 collectin sub-family member 11
COLEC12 collectin sub-family member 12
CTTN cortactin
CUBN cubilin (intrinsic factor-cobalamin receptor)
CXCL16 chemokine (C-X-C motif) ligand 16
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBNL drebrin-like
DMBT1 deleted in malignant brain tumors 1
DNM1 dynamin 1
DNM2 dynamin 2
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
ENDOU endonuclease, polyU-specific
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
EPS15 epidermal growth factor receptor pathway substrate 15
EZR ezrin
FCHO1 FCH domain only 1
FCHO2 FCH domain only 2
FNBP1L formin binding protein 1-like
FOLR1 folate receptor 1 (adult)
FTH1 ferritin, heavy polypeptide 1
FTL ferritin, light polypeptide
GAK cyclin G associated kinase
GRB2 growth factor receptor-bound protein 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK4 G protein-coupled receptor kinase 4
HBB hemoglobin, beta
HHIPL1 HHIP-like 1
HIP1R huntingtin interacting protein 1 related
HP haptoglobin
HPR haptoglobin-related protein
HPX hemopexin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPH1 heat shock 105kDa/110kDa protein 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HYOU1 hypoxia up-regulated 1
IGF2R insulin-like growth factor 2 receptor
ILDR1 immunoglobulin-like domain containing receptor 1
LDLR low density lipoprotein receptor
LDLRAD3 low density lipoprotein receptor class A domain containing 3
LDLRAP1 low density lipoprotein receptor adaptor protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMBRD1 LMBR1 domain containing 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
LRP1 low density lipoprotein receptor-related protein 1
LRP12 low density lipoprotein receptor-related protein 12
LRP1B low density lipoprotein receptor-related protein 1B
LRP2 low density lipoprotein receptor-related protein 2
LRP3 low density lipoprotein receptor-related protein 3
LRP6 low density lipoprotein receptor-related protein 6
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRPAP1 low density lipoprotein receptor-related protein associated protein 1
M6PR mannose-6-phosphate receptor (cation dependent)
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MARCO macrophage receptor with collagenous structure
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MICALL1 MICAL-like 1
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MRC1 mannose receptor, C type 1
MSR1 macrophage scavenger receptor 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NLGN3 neuroligin 3
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PGBD1 piggyBac transposable element derived 1
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PICALM phosphatidylinositol binding clathrin assembly protein
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PPT1 palmitoyl-protein thioesterase 1
PRG4 proteoglycan 4
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB31 RAB31, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAMP3 receptor (G protein-coupled) activity modifying protein 3
REPS1 RALBP1 associated Eps domain containing 1
SAA1 serum amyloid A1
SBSPON somatomedin B and thrombospondin, type 1 domain containing
SCARA3 scavenger receptor class A, member 3
SCARA5 scavenger receptor class A, member 5
SCARB1 scavenger receptor class B, member 1
SCARF1 scavenger receptor class F, member 1
SCARF2 scavenger receptor class F, member 2
SCGB3A2 secretoglobin, family 3A, member 2
SCYL2 SCY1-like 2 (S. cerevisiae)
SFTPD surfactant protein D
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNX1 sorting nexin 1
SNX17 sorting nexin 17
SNX9 sorting nexin 9
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SSC4D scavenger receptor cysteine rich family, 4 domains
SSC5D scavenger receptor cysteine rich family, 5 domains
STAB1 stabilin 1
STAB2 stabilin 2
SUSD2 sushi domain containing 2
TFR2 transferrin receptor 2
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TINAG tubulointerstitial nephritis antigen
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMPRSS13 transmembrane protease, serine 13
TMPRSS15 transmembrane protease, serine 15
TMPRSS2 transmembrane protease, serine 2
TMPRSS3 transmembrane protease, serine 3
TMPRSS4 transmembrane protease, serine 4
TMPRSS5 transmembrane protease, serine 5
ULK1 unc-51 like autophagy activating kinase 1
VLDLR very low density lipoprotein receptor
VTN vitronectin