rectal disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

153 genes co-occuring with the disease rectal disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
APOLD1 apolipoprotein L domain containing 1 1.92811
KLK3 kallikrein-related peptidase 3 1.3869
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.963728
PLEK2 pleckstrin 2 0.89623
CD6 CD6 molecule 0.882701
NXN nucleoredoxin 0.880653
ANKRD11 ankyrin repeat domain 11 0.735433
CAMKV CaM kinase-like vesicle-associated 0.725311
NMUR2 neuromedin U receptor 2 0.719654
CD4 CD4 molecule 0.715215
FREM1 FRAS1 related extracellular matrix 1 0.697911
TADA3 transcriptional adaptor 3 0.696707
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.696306
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.683093
ALAS1 5'-aminolevulinate synthase 1 0.663181
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.65288
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.65288
DYM dymeclin 0.650113
TAGAP T-cell activation RhoGTPase activating protein 0.644586
SUCLG1 succinate-CoA ligase, alpha subunit 0.581217
STK10 serine/threonine kinase 10 0.570718
PITX1 paired-like homeodomain 1 0.56722
CD68 CD68 molecule 0.555956
CAMP cathelicidin antimicrobial peptide 0.531541
ASMT acetylserotonin O-methyltransferase 0.52343
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.502675
SAMM50 SAMM50 sorting and assembly machinery component 0.492359
GSAP gamma-secretase activating protein 0.491597
LAX1 lymphocyte transmembrane adaptor 1 0.490454
MPO myeloperoxidase 0.478289
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.478289
LTF lactotransferrin 0.475634
PATE1 prostate and testis expressed 1 0.471089
FLNA filamin A, alpha 0.467306
DYNLRB1 dynein, light chain, roadblock-type 1 0.450324
TNF tumor necrosis factor 0.442795
HDGF hepatoma-derived growth factor 0.442795
CD79A CD79a molecule, immunoglobulin-associated alpha 0.440538
PLAU plasminogen activator, urokinase 0.431519
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.425139
NOD2 nucleotide-binding oligomerization domain containing 2 0.415398
EPX eosinophil peroxidase 0.40904
PLCH2 phospholipase C, eta 2 0.407172
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.39598
C5ORF38 chromosome 5 open reading frame 38 0.393374
MED28 mediator complex subunit 28 0.383708
FBLN1 fibulin 1 0.377031
FBLN5 fibulin 5 0.36741
OPRL1 opiate receptor-like 1 0.354499
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.352659
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.349717
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.3292
CRP C-reactive protein, pentraxin-related 0.318272
CXCL8 chemokine (C-X-C motif) ligand 8 0.313915
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.313915
EED embryonic ectoderm development 0.308842
ALB albumin 0.295492
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.294413
DYNLT1 dynein, light chain, Tctex-type 1 0.291898
CRYGD crystallin, gamma D 0.287593
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.284371
PPP4C protein phosphatase 4, catalytic subunit 0.280082
TLR6 toll-like receptor 6 0.270108
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.264431
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.249257
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.248203
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.243645
TGFB2 transforming growth factor, beta 2 0.238752
KNTC1 kinetochore associated 1 0.234573
BMPR1A bone morphogenetic protein receptor, type IA 0.232142
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.230755
TOX thymocyte selection-associated high mobility group box 0.230063
PER1 period circadian clock 1 0.228679
MMP8 matrix metallopeptidase 8 0.227988
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.218374
NCOA1 nuclear receptor coactivator 1 0.213621
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.212271
S100A12 S100 calcium binding protein A12 0.195501
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.191408
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.191097
COL3A1 collagen, type III, alpha 1 0.182375
LYZ lysozyme 0.181222
NOS1 nitric oxide synthase 1 (neuronal) 0.180652
A1BG alpha-1-B glycoprotein 0.17952
MRAP melanocortin 2 receptor accessory protein 0.175411
TCN2 transcobalamin II 0.172291
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.168617
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.161912
CCNA2 cyclin A2 0.158778
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.157765
WDFY2 WD repeat and FYVE domain containing 2 0.141538
CELA1 chymotrypsin-like elastase family, member 1 0.132326
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.132313
FUT2 fucosyltransferase 2 (secretor status included) 0.132106
CELA3B chymotrypsin-like elastase family, member 3B 0.131967
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.131549
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.13143
PRL prolactin 0.131386
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.131236
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.131007
LARS leucyl-tRNA synthetase 0.130913
GPANK1 G patch domain and ankyrin repeats 1 0.130772
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.130402
FBL fibrillarin 0.13002
GATA4 GATA binding protein 4 0.129711
PYY peptide YY 0.129694
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.12966
RAG2 recombination activating gene 2 0.12927
TGFB3 transforming growth factor, beta 3 0.127856
LCT lactase 0.127425
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.127342
FBLL1 fibrillarin-like 1 0.127237
ACE2 angiotensin I converting enzyme 2 0.126829
LDHA lactate dehydrogenase A 0.126564
IRF6 interferon regulatory factor 6 0.126475
GLUL glutamate-ammonia ligase 0.126251
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.125883
GAA glucosidase, alpha; acid 0.125647
CYGB cytoglobin 0.125044
FHIT fragile histidine triad 0.124028
NELFCD negative elongation factor complex member C/D 0.121094
RNASE3 ribonuclease, RNase A family, 3 0.120722
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.120595
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.120563
PDE5A phosphodiesterase 5A, cGMP-specific 0.120114
PLG plasminogen 0.120082
TLR1 toll-like receptor 1 0.11922
ADM adrenomedullin 0.119117
PTEN phosphatase and tensin homolog 0.119015
PRRC2A proline-rich coiled-coil 2A 0.118498
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.117862
THBD thrombomodulin 0.117753
HBA1 hemoglobin, alpha 1 0.11768
IL1B interleukin 1, beta 0.116456
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.116188
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.116149
AHR aryl hydrocarbon receptor 0.115877
TYMS thymidylate synthetase 0.1158
HBA2 hemoglobin, alpha 2 0.115528
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.115488
ANG angiogenin, ribonuclease, RNase A family, 5 0.115288
NOS3 nitric oxide synthase 3 (endothelial cell) 0.115248
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.114646
CFP complement factor properdin 0.113902
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.113861
TBX1 T-box 1 0.113734
NOS2 nitric oxide synthase 2, inducible 0.11301
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.112618
TLR9 toll-like receptor 9 0.111008
HLA-E major histocompatibility complex, class I, E 0.110728
MMP7 matrix metallopeptidase 7 0.110635
ATM ATM serine/threonine kinase 0.110635
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.110217