regarding Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

259 genes co-occuring with the biological term regarding in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ADAM12 ADAM metallopeptidase domain 12
ADAM17 ADAM metallopeptidase domain 17
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2B adenosine A2b receptor
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AIP aryl hydrocarbon receptor interacting protein
ALK anaplastic lymphoma receptor tyrosine kinase
APOA1 apolipoprotein A-I
APOA2 apolipoprotein A-II
APOA5 apolipoprotein A-V
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARMS2 age-related maculopathy susceptibility 2
AVPR2 arginine vasopressin receptor 2
BIRC5 baculoviral IAP repeat containing 5
BMP15 bone morphogenetic protein 15
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C19ORF80 chromosome 19 open reading frame 80
C3 complement component 3
CAV1 caveolin 1, caveolae protein, 22kDa
CBFB core-binding factor, beta subunit
CCK cholecystokinin
CCL22 chemokine (C-C motif) ligand 22
CCND1 cyclin D1
CD24 CD24 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD81 CD81 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFH complement factor H
CFHR5 complement factor H-related 5
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DCLK1 doublecortin-like kinase 1
DMD dystrophin
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
EZR ezrin
F10 coagulation factor X
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FABP2 fatty acid binding protein 2, intestinal
FASLG Fas ligand (TNF superfamily, member 6)
FGFR3 fibroblast growth factor receptor 3
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT4 fms-related tyrosine kinase 4
FMR1 fragile X mental retardation 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP3 forkhead box P3
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLA galactosidase, alpha
GPX1 glutathione peroxidase 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRN granulin
GSTM1 glutathione S-transferase mu 1
H2AFZ H2A histone family, member Z
HARS histidyl-tRNA synthetase
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRH4 histamine receptor H4
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA4 heat shock 70kDa protein 4
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
IDO1 indoleamine 2,3-dioxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGH immunoglobulin heavy locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL22 interleukin 22
IL32 interleukin 32
IL6 interleukin 6
ILK integrin-linked kinase
INHBB inhibin, beta B
IRF6 interferon regulatory factor 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
KHDC3L KH domain containing 3-like, subcortical maternal complex member
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK4 kallikrein-related peptidase 4
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS3 lectin, galactoside-binding, soluble, 3
LHCGR luteinizing hormone/choriogonadotropin receptor
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAOB monoamine oxidase B
MAP2 microtubule-associated protein 2
MASP2 mannan-binding lectin serine peptidase 2
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MC4R melanocortin 4 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MFN2 mitofusin 2
MGMT O-6-methylguanine-DNA methyltransferase
MIR146B microRNA 146b
MIR200A microRNA 200a
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPL MPL proto-oncogene, thrombopoietin receptor
MSTN myostatin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MYH11 myosin, heavy chain 11, smooth muscle
NASP nuclear autoantigenic sperm protein (histone-binding)
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NEFL neurofilament, light polypeptide
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NOD1 nucleotide-binding oligomerization domain containing 1
NPPB natriuretic peptide B
NPS neuropeptide S
NPSR1 neuropeptide S receptor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OPA1 optic atrophy 1 (autosomal dominant)
OPTN optineurin
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAH phenylalanine hydroxylase
PARK2 parkin RBR E3 ubiquitin protein ligase
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDYN prodynorphin
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PINK1 PTEN induced putative kinase 1
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLCD1 phospholipase C, delta 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POR P450 (cytochrome) oxidoreductase
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRNP prion protein
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RAB25 RAB25, member RAS oncogene family
REN renin
RETN resistin
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
S100B S100 calcium binding protein B
SCARA3 scavenger receptor class A, member 3
SCARB1 scavenger receptor class B, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT6 sirtuin 6
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC46A1 solute carrier family 46 (folate transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
STK11 serine/threonine kinase 11
STX1A syntaxin 1A (brain)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMSB10 thymosin beta 10
TMSB4X thymosin beta 4, X-linked
TNF tumor necrosis factor
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNI3 troponin I type 3 (cardiac)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP73 tumor protein p73
TRB T cell receptor beta locus
TSHR thyroid stimulating hormone receptor
TSPO translocator protein (18kDa)
TYMS thymidylate synthetase
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGT1A UDP glucuronosyltransferase 1 family, polypeptide A complex locus
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VKORC1 vitamin K epoxide reductase complex, subunit 1
VWF von Willebrand factor
WLS wntless Wnt ligand secretion mediator
WRN Werner syndrome, RecQ helicase-like
WT1 Wilms tumor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFPM2 zinc finger protein, FOG family member 2