regulation of GTPase activity Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate of GTP hydrolysis by a GTPase. (Gene Ontology, GO_0043087)
External Link http://amigo.geneontology.org/amigo/term/GO:0043087
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Genes

135 genes participating in the regulation of GTPase activity biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AGRN agrin
ALS2 amyotrophic lateral sclerosis 2 (juvenile)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP11A Rho GTPase activating protein 11A
ARHGAP11B Rho GTPase activating protein 11B
ARHGAP44 Rho GTPase activating protein 44
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL2 ADP-ribosylation factor-like 2
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
BCAR3 breast cancer anti-estrogen resistance 3
BVES blood vessel epicardial substance
CAV2 caveolin 2
CCL11 chemokine (C-C motif) ligand 11
CCL19 chemokine (C-C motif) ligand 19
CCL24 chemokine (C-C motif) ligand 24
CCL26 chemokine (C-C motif) ligand 26
CFAP73 cilia and flagella associated protein 73
CRK v-crk avian sarcoma virus CT10 oncogene homolog
DAB2IP DAB2 interacting protein
DOCK10 dedicator of cytokinesis 10
DOCK11 dedicator of cytokinesis 11
DOCK8 dedicator of cytokinesis 8
DOCK9 dedicator of cytokinesis 9
DVL3 dishevelled segment polarity protein 3
ECT2 epithelial cell transforming 2
EFNA5 ephrin-A5
EPHA1 EPH receptor A1
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EPHA5 EPH receptor A5
EPHB3 EPH receptor B3
EVI5 ecotropic viral integration site 5
EVI5L ecotropic viral integration site 5-like
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
FGD1 FYVE, RhoGEF and PH domain containing 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGD5 FYVE, RhoGEF and PH domain containing 5
FGD6 FYVE, RhoGEF and PH domain containing 6
FICD FIC domain containing
GMIP GEM interacting protein
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPR137B G protein-coupled receptor 137B
GPSM1 G-protein signaling modulator 1
HRAS Harvey rat sarcoma viral oncogene homolog
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LARS1 leucyl-tRNA synthetase 1
LIMS1 LIM and senescent cell antigen-like domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRK2 leucine-rich repeat kinase 2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MMUT methylmalonyl-CoA mutase
NDEL1 nudE neurodevelopment protein 1-like 1
NF1 neurofibromin 1
NGEF neuronal guanine nucleotide exchange factor
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ODAM odontogenic, ameloblast asssociated
PDZD2 PDZ domain containing 2
PKP4 plakophilin 4
PLXNB1 plexin B1
PLXNB2 plexin B2
PLXNB3 plexin B3
PRKG1 protein kinase, cGMP-dependent, type I
PROM2 prominin 2
PRPF38B pre-mRNA processing factor 38B
PRTN3 proteinase 3
PTK2 protein tyrosine kinase 2
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABGAP1 RAB GTPase activating protein 1
RACK1 receptor for activated C kinase 1
RAP1A RAP1A, member of RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASA4 RAS p21 protein activator 4
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASIP1 Ras interacting protein 1
RCC2 regulator of chromosome condensation 2
RDX radixin
REPS1 RALBP1 associated Eps domain containing 1
RGPD1 RANBP2-like and GRIP domain containing 1
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
RGS16 regulator of G-protein signaling 16
RGS6 regulator of G-protein signaling 6
RGS7 regulator of G-protein signaling 7
RGS8 regulator of G-protein signaling 8
RIC1 RAB6A GEF complex partner 1
RRP1B ribosomal RNA processing 1B
RSU1 Ras suppressor protein 1
RTN4R reticulon 4 receptor
S100A10 S100 calcium binding protein A10
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGSM2 small G protein signaling modulator 2
SGSM3 small G protein signaling modulator 3
SH3BP1 SH3-domain binding protein 1
SH3BP4 SH3-domain binding protein 4
SIPA1L1 signal-induced proliferation-associated 1 like 1
SNX13 sorting nexin 13
SNX18 sorting nexin 18
SNX9 sorting nexin 9
SOD1 superoxide dismutase 1, soluble
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
TBC1D10B TBC1 domain family, member 10B
TBC1D15 TBC1 domain family, member 15
TBC1D2 TBC1 domain family, member 2
TBC1D20 TBC1 domain family, member 20
TBC1D30 TBC1 domain family, member 30
TBC1D7 TBC1 domain family, member 7
TGM2 transglutaminase 2
THY1 Thy-1 cell surface antigen
TMED2 transmembrane emp24 domain trafficking protein 2
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP6NL USP6 N-terminal like
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
ZC3H15 zinc finger CCCH-type containing 15