regulation of MAPK cascade Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade. (Gene Ontology, GO_0043408)
External Link http://amigo.geneontology.org/amigo/term/GO_0043408
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Genes

205 genes participating in the regulation of MAPK cascade biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADRA1B adrenoceptor alpha 1B
ADRA1D adrenoceptor alpha 1D
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
ALOX12B arachidonate 12-lipoxygenase, 12R type
APIP APAF1 interacting protein
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ART4 ADP-ribosyltransferase 4 (Dombrock blood group)
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AVPI1 arginine vasopressin-induced 1
AVPR1B arginine vasopressin receptor 1B
BCAR3 breast cancer anti-estrogen resistance 3
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
CARTPT CART prepropeptide
CASC2 cancer susceptibility candidate 2 (non-protein coding)
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CAV3 caveolin 3
CCNA2 cyclin A2
CD24 CD24 molecule
CD4 CD4 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD81 CD81 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CSF1R colony stimulating factor 1 receptor
CX3CL1 chemokine (C-X3-C motif) ligand 1
DAB2IP DAB2 interacting protein
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DHX33 DEAH (Asp-Glu-Ala-His) box polypeptide 33
DOK2 docking protein 2, 56kDa
DOK3 docking protein 3
DOK4 docking protein 4
DOK5 docking protein 5
DOK6 docking protein 6
DUPD1 dual specificity phosphatase and pro isomerase domain containing 1
DUSP1 dual specificity phosphatase 1
DUSP13 dual specificity phosphatase 13
DUSP16 dual specificity phosphatase 16
DUSP19 dual specificity phosphatase 19
DUSP2 dual specificity phosphatase 2
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
DUSP7 dual specificity phosphatase 7
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EPHA2 EPH receptor A2
EPHA7 EPH receptor A7
EPHA8 EPH receptor A8
EPHB1 EPH receptor B1
ERBB2 erb-b2 receptor tyrosine kinase 2
ETFA electron-transfer-flavoprotein, alpha polypeptide
F2R coagulation factor II (thrombin) receptor
FAS Fas cell surface death receptor
FCRL3 Fc receptor-like 3
FGF10 fibroblast growth factor 10
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
GDF15 growth differentiation factor 15
GFRAL GDNF family receptor alpha like
GHRL ghrelin/obestatin prepropeptide
GPER1 G protein-coupled estrogen receptor 1
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR37L1 G protein-coupled receptor 37 like 1
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GREM1 gremlin 1, DAN family BMP antagonist
GRM4 glutamate receptor, metabotropic 4
GSDME gasdermin E
GSTP1 glutathione S-transferase pi 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HRAS Harvey rat sarcoma viral oncogene homolog
IAPP islet amyloid polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP6 insulin-like growth factor binding protein 6
IL11 interleukin 11
IL1B interleukin 1, beta
IL6 interleukin 6
INAVA innate immunity activator
INS insulin
INSR insulin receptor
IQGAP1 IQ motif containing GTPase activating protein 1
JCAD junctional cadherin 5 associated
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KSR1 kinase suppressor of ras 1
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAPTM5 lysosomal protein transmembrane 5
LBH limb bud and heart development
LEP leptin
LIF leukemia inhibitory factor
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LILRP2 leukocyte immunoglobulin-like receptor pseudogene 2
LPAR1 lysophosphatidic acid receptor 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MINK1 misshapen-like kinase 1
MMP8 matrix metallopeptidase 8
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MYDGF myeloid-derived growth factor
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NBR1 neighbor of BRCA1 gene 1
NEK10 NIMA-related kinase 10
NF1 neurofibromin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OSM oncostatin M
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAGE4 P antigen family, member 4 (prostate associated)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PELI2 pellino E3 ubiquitin protein ligase family member 2
PHB2 prohibitin 2
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PLCE1 phospholipase C, epsilon 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPEF2 protein phosphatase, EF-hand calcium binding domain 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDM11 PR domain containing 11
PRDM15 PR domain containing 15
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRJ protein tyrosine phosphatase, receptor type, J
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
REN renin
RET ret proto-oncogene
RIT2 Ras-like without CAAX 2
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RRAS related RAS viral (r-ras) oncogene homolog
RYK receptor-like tyrosine kinase
SACK1D scaffolding CK1 anchoring protein D
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLA Src-like-adaptor
SOD1 superoxide dismutase 1, soluble
SOX2 SRY (sex determining region Y)-box 2
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY3 sprouty homolog 3 (Drosophila)
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
STYX serine/threonine/tyrosine interacting protein
STYXL2 serine/threonine/tyrosine interacting like 2
SYK spleen tyrosine kinase
TAOK2 TAO kinase 2
TAOK3 TAO kinase 3
TBX1 T-box 1
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TGFBR1 transforming growth factor, beta receptor 1
TGFBR3 transforming growth factor, beta receptor III
THPO thrombopoietin
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR9 toll-like receptor 9
TMEM106A transmembrane protein 106A
TNF tumor necrosis factor
TNIK TRAF2 and NCK interacting kinase
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase
TRIM5 tripartite motif containing 5
ULK4 unc-51 like kinase 4
VRK2 vaccinia related kinase 2
WDR54 WD repeat domain 54
WWC1 WW and C2 domain containing 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF622 zinc finger protein 622