regulation of Wnt signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway. (Gene Ontology, GO_0030111)
External Link http://amigo.geneontology.org/amigo/term/GO:0030111
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Genes

113 genes participating in the regulation of Wnt signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AMER1 APC membrane recruitment protein 1
AMER2 APC membrane recruitment protein 2
AMER3 APC membrane recruitment protein 3
APCDD1 adenomatosis polyposis coli down-regulated 1
APP amyloid beta (A4) precursor protein
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
BMP2 bone morphogenetic protein 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C12ORF43 chromosome 12 open reading frame 43
C1D C1D nuclear receptor corepressor
CBY1 chibby homolog 1 (Drosophila)
CCDC134 coiled-coil domain containing 134
CCNY cyclin Y
CCNYL1 cyclin Y-like 1
CCNYL1B cyclin Y like 1B
CDC73 cell division cycle 73
CDK14 cyclin-dependent kinase 14
CER1 cerberus 1, DAN family BMP antagonist
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CRBN cereblon
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTNNBIP1 catenin, beta interacting protein 1
CTNND2 catenin (cadherin-associated protein), delta 2
CXXC4 CXXC finger protein 4
DAAM2 dishevelled associated activator of morphogenesis 2
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DCDC2 doublecortin domain containing 2
DEPDC1B DEP domain containing 1B
DISC1 disrupted in schizophrenia 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK4 dickkopf WNT signaling pathway inhibitor 4
EMD emerin
FAM53B family with sequence similarity 53, member B
FGFR2 fibroblast growth factor receptor 2
FOLR2 folate receptor 2 (fetal)
FOXL1 forkhead box L1
FRZB frizzled-related protein
FZD7 frizzled class receptor 7
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC3 glypican 3
GRB10 growth factor receptor-bound protein 10
GSKIP GSK3B interacting protein
HHEX hematopoietically expressed homeobox
HIC1 hypermethylated in cancer 1
HMGXB4 HMG box domain containing 4
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KANK1 KN motif and ankyrin repeat domains 1
KREMEN1 kringle containing transmembrane protein 1
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LRRK2 leucine-rich repeat kinase 2
MACF1 microtubule-actin crosslinking factor 1
MDFI MyoD family inhibitor
MDFIC MyoD family inhibitor domain containing
MDFIC2 MyoD family inhibitor domain containing 2
NKD1 naked cuticle homolog 1 (Drosophila)
NKD2 naked cuticle homolog 2 (Drosophila)
NLK nemo-like kinase
NOTUM notum pectinacetylesterase homolog (Drosophila)
NXN nucleoredoxin
OTULIN OTU deubiquitinase with linear linkage specificity
PCDH11Y protocadherin 11 Y-linked
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKN parkin RBR E3 ubiquitin protein ligase
PSEN1 presenilin 1
PTK7 protein tyrosine kinase 7 (inactive)
RACK1 receptor for activated C kinase 1
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RNF14 ring finger protein 14
RNF43 ring finger protein 43
RSPO1 R-spondin 1
RSPO2 R-spondin 2
RSPO3 R-spondin 3
RSPO4 R-spondin 4
SALL1 spalt-like transcription factor 1
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SHISA2 shisa family member 2
SKI SKI proto-oncogene
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNX3 sorting nexin 3
SOST sclerostin
SOSTDC1 sclerostin domain containing 1
SOX30 SRY (sex determining region Y)-box 30
SPNS1 spinster homolog 1 (Drosophila)
STK11 serine/threonine kinase 11
SULF1 sulfatase 1
SULF2 sulfatase 2
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TERT telomerase reverse transcriptase
TIAM1 T-cell lymphoma invasion and metastasis 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR2 toll-like receptor 2
TMEM237 transmembrane protein 237
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRABD2A TraB domain containing 2A
TRABD2B TraB domain containing 2B
TSC2 tuberous sclerosis 2
TSKU tsukushi, small leucine rich proteoglycan
VGLL4 vestigial-like family member 4
WIF1 WNT inhibitory factor 1
WLS wntless Wnt ligand secretion mediator
WWOX WW domain containing oxidoreductase
ZNF703 zinc finger protein 703
ZRANB1 zinc finger, RAN-binding domain containing 1