regulation of angiogenesis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of angiogenesis. (Gene Ontology, GO_0045765)
External Link http://amigo.geneontology.org/amigo/term/GO:0045765
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Genes

212 genes participating in the regulation of angiogenesis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA2 adhesion G protein-coupled receptor A2
ADGRB1 adhesion G protein-coupled receptor B1
ADM2 adrenomedullin 2
AGGF1 angiogenic factor with G patch and FHA domains 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
ALOX5 arachidonate 5-lipoxygenase
AMOT angiomotin
ANGPT4 angiopoietin 4
ANGPTL3 angiopoietin-like 3
ANGPTL4 angiopoietin-like 4
ANXA3 annexin A3
APELA apelin receptor early endogenous ligand
APLNR apelin receptor
APOH apolipoprotein H (beta-2-glycoprotein I)
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BMPER BMP binding endothelial regulator
BRCA1 breast cancer 1, early onset
BTG1 B-cell translocation gene 1, anti-proliferative
CCM2 cerebral cavernous malformation 2
CCN6 cellular communication network factor 6
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CD160 CD160 molecule
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH5 cadherin 5, type 2 (vascular endothelium)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMIP2 cell migration inducing hyaluronidase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLDN5 claudin 5
CLSTN1 calsyntenin 1
CNMD chondromodulin
COL4A2 collagen, type IV, alpha 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSH cathepsin H
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2IP DAB2 interacting protein
DAND5 DAN domain family member 5, BMP antagonist
DCN decorin
ECM1 extracellular matrix protein 1
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
EFNA3 ephrin-A3
EGLN1 egl-9 family hypoxia-inducible factor 1
EMC10 ER membrane protein complex subunit 10
EMILIN1 elastin microfibril interfacer 1
EMILIN2 elastin microfibril interfacer 2
EMP2 epithelial membrane protein 2
EPHA1 EPH receptor A1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F3 coagulation factor III (thromboplastin, tissue factor)
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FGF13 fibroblast growth factor 13
FGF16 fibroblast growth factor 16
FGF18 fibroblast growth factor 18
FLT1 fms-related tyrosine kinase 1
FOXC1 forkhead box C1
FOXJ2 forkhead box J2
FOXO4 forkhead box O4
GATA2 GATA binding protein 2
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GDF2 growth differentiation factor 2
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
GTF2I general transcription factor IIi
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HHEX hematopoietically expressed homeobox
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HOOK2 hook microtubule-tethering protein 2
HOXA5 homeobox A5
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPG2 heparan sulfate proteoglycan 2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IL17F interleukin 17F
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
ISL1 ISL LIM homeobox 1
ISM1 isthmin 1, angiogenesis inhibitor
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB8 integrin, beta 8
JUP junction plakoglobin
KDR kinase insert domain receptor
KLF4 Kruppel-like factor 4 (gut)
KLKB1 kallikrein B, plasma (Fletcher factor) 1
KRIT1 KRIT1, ankyrin repeat containing
KRT1 keratin 1, type II
LEP leptin
LRG1 leucine-rich alpha-2-glycoprotein 1
MECP2 methyl CpG binding protein 2
MINAR1 membrane integral NOTCH2 associated receptor 1
MINDY4 MINDY lysine 48 deubiquitinase 4
MTDH metadherin
MYDGF myeloid-derived growth factor
NANOS3 nanos homolog 3 (Drosophila)
NAXE NAD(P)HX epimerase
NF1 neurofibromin 1
NINJ1 ninjurin 1
NODAL nodal growth differentiation factor
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
OR10J5 olfactory receptor, family 10, subfamily J, member 5
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PDCD10 programmed cell death 10
PDCD6 programmed cell death 6
PDCL3 phosducin-like 3
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDPK1 3-phosphoinositide dependent protein kinase 1
PF4 platelet factor 4
PGK1 phosphoglycerate kinase 1
PIGU phosphatidylinositol glycan anchor biosynthesis, class U
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6
PLCG1 phospholipase C, gamma 1
PLXND1 plexin D1
PML promyelocytic leukemia
PPARG peroxisome proliferator-activated receptor gamma
PPP1R16B protein phosphatase 1, regulatory subunit 16B
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRL prolactin
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRM protein tyrosine phosphatase, receptor type, M
QKI QKI, KH domain containing, RNA binding
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGCC regulator of cell cycle
RHOB ras homolog family member B
RHOJ ras homolog family member J
RLN2 relaxin 2
RNASEH1 ribonuclease H1
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RRAS related RAS viral (r-ras) oncogene homolog
RTN4 reticulon 4
RUNX1 runt-related transcription factor 1
SARS1 seryl-tRNA synthetase 1
SASH1 SAM and SH3 domain containing 1
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMOC2 SPARC related modular calcium binding 2
SP100 SP100 nuclear antigen
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRED1 sprouty-related, EVH1 domain containing 1
SPRY2 sprouty homolog 2 (Drosophila)
STAB1 stabilin 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STIM1 stromal interaction molecule 1
SULF1 sulfatase 1
SYNJ2BP synaptojanin 2 binding protein
TEK TEK tyrosine kinase, endothelial
TGFB2 transforming growth factor, beta 2
THBS1 thrombospondin 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNMD tenomodulin
TSPAN12 tetraspanin 12
TSPAN18 tetraspanin 18
TWIST1 twist family bHLH transcription factor 1
VASH1 vasohibin 1
VASH2 vasohibin 2
VEGFA vascular endothelial growth factor A
WARS1 tryptophanyl-tRNA synthetase 1
WNK1 WNK lysine deficient protein kinase 1
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
YJEFN3 YjeF N-terminal domain containing 3
ZC3H12A zinc finger CCCH-type containing 12A
ZNF304 zinc finger protein 304