regulation of apoptotic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the occurrence or rate of cell death by apoptotic process. (Gene Ontology, GO_0042981)
External Link http://amigo.geneontology.org/amigo/term/GO:0042981
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Genes

705 genes participating in the regulation of apoptotic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACER2 alkaline ceramidase 2
ACIN1 apoptotic chromatin condensation inducer 1
ACTL6A actin-like 6A
ACTN1 actinin, alpha 1
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACTN4 actinin, alpha 4
ACVR1C activin A receptor, type IC
ADAMTSL4 ADAMTS-like 4
AGXT alanine-glyoxylate aminotransferase
AHI1 Abelson helper integration site 1
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AIFM2 apoptosis-inducing factor, mitochondrion-associated, 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK2 alpha-kinase 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT1 angiopoietin 1
ANGPT4 angiopoietin 4
ANGPTL4 angiopoietin-like 4
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD13C ankyrin repeat domain 13C
ANO6 anoctamin 6
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
ANXA1 annexin A1
ANXA4 annexin A4
ANXA5 annexin A5
APAF1 apoptotic peptidase activating factor 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
API5 apoptosis inhibitor 5
APIP APAF1 interacting protein
APP amyloid beta (A4) precursor protein
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1
ARF4 ADP-ribosylation factor 4
ARHGAP10 Rho GTPase activating protein 10
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARMC10 armadillo repeat containing 10
ASCL1 achaete-scute family bHLH transcription factor 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATAD3A ATPase family, AAA domain containing 3A
ATF4 activating transcription factor 4
ATF5 activating transcription factor 5
ATF6 activating transcription factor 6
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
AVEN apoptosis, caspase activation inhibitor
AXL AXL receptor tyrosine kinase
AZU1 azurocidin 1
BABAM2 BRISC and BRCA1 A complex member 2
BAD BCL2-associated agonist of cell death
BAG1 BCL2-associated athanogene
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BAK1 BCL2-antagonist/killer 1
BARD1 BRCA1 associated RING domain 1
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L12 BCL2-like 12 (proline rich)
BCL2L2 BCL2-like 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCLAF1 BCL2-associated transcription factor 1
BEX2 brain expressed X-linked 2
BFAR bifunctional apoptosis regulator
BID BH3 interacting domain death agonist
BIK BCL2-interacting killer (apoptosis-inducing)
BIN1 bridging integrator 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BIRC6 baculoviral IAP repeat containing 6
BIRC7 baculoviral IAP repeat containing 7
BLID BH3-like motif containing, cell death inducer
BMF Bcl2 modifying factor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BOK BCL2-related ovarian killer
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD8 bromodomain containing 8
BRMS1L breast cancer metastasis-suppressor 1-like
C1QBP complement component 1, q subcomponent binding protein
C3ORF38 chromosome 3 open reading frame 38
CAAP1 caspase activity and apoptosis inhibitor 1
CALHM2 calcium homeostasis modulator 2
CALR calreticulin
CAPN3 calpain 3, (p94)
CARD14 caspase recruitment domain family, member 14
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX4 chromobox homolog 4
CCAR1 cell division cycle and apoptosis regulator 1
CCAR2 cell cycle and apoptosis regulator 2
CCND2 cyclin D2
CCNL1 cyclin L1
CCNL2 cyclin L2
CD27 CD27 molecule
CD28 CD28 molecule
CD38 CD38 molecule
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK5 cyclin-dependent kinase 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CERKL ceramide kinase-like
CFLAR CASP8 and FADD-like apoptosis regulator
CIAPIN1 cytokine induced apoptosis inhibitor 1
CIB1 calcium and integrin binding 1 (calmyrin)
CIDEA cell death-inducing DFFA-like effector a
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC5A C-type lectin domain family 5, member A
CLIP3 CAP-GLY domain containing linker protein 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CLU clusterin
COMP cartilage oligomeric matrix protein
COPS5 COP9 signalosome subunit 5
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CREB1 cAMP responsive element binding protein 1
CREB3L4 cAMP responsive element binding protein 3-like 4
CRIPTO3 cripto, EGF-CFC family member 3
CRYAB crystallin, alpha B
CSRNP3 cysteine-serine-rich nuclear protein 3
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBL1 catenin, beta like 1
CTSB cathepsin B
CTSD cathepsin D
CTSH cathepsin H
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL10 chemokine (C-X-C motif) ligand 10
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DCUN1D3 DCN1, defective in cullin neddylation 1, domain containing 3
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDRGK1 DDRGK domain containing 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIABLO diablo, IAP-binding mitochondrial protein
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKKL1 dickkopf-like 1
DMAP1 DNA methyltransferase 1 associated protein 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNM2 dynamin 2
DSG2 desmoglein 2
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP6 dual specificity phosphatase 6
DYNAP dynactin associated protein
E2F1 E2F transcription factor 1
ECT2 epithelial cell transforming 2
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EGLN2 egl-9 family hypoxia-inducible factor 2
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
EGR3 early growth response 3
EMILIN1 elastin microfibril interfacer 1
EMILIN2 elastin microfibril interfacer 2
EP400 E1A binding protein p400
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPC2 enhancer of polycomb homolog 2 (Drosophila)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC3 excision repair cross-complementation group 3
ERCC5 excision repair cross-complementation group 5
ERFE erythroferrone
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EVI2B ecotropic viral integration site 2B
F2R coagulation factor II (thrombin) receptor
FADD Fas (TNFRSF6)-associated via death domain
FAF1 Fas (TNFRSF6) associated factor 1
FAIM2 Fas apoptotic inhibitory molecule 2
FAM162A family with sequence similarity 162, member A
FANK1 fibronectin type III and ankyrin repeat domains 1
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FATE1 fetal and adult testis expressed 1
FBXO10 F-box protein 10
FBXO11 F-box protein 11
FCMR Fc fragment of IgM receptor
FFAR4 free fatty acid receptor 4
FHL2 four and a half LIM domains 2
FIGNL1 fidgetin-like 1
FKBP8 FK506 binding protein 8, 38kDa
FLCN folliculin
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FMN2 formin 2
FOXA1 forkhead box A1
FOXE3 forkhead box E3
FOXL2 forkhead box L2
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FRZB frizzled-related protein
FSTL1 follistatin-like 1
FXN frataxin
FZD9 frizzled class receptor 9
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GADD45G growth arrest and DNA-damage-inducible, gamma
GAS1 growth arrest-specific 1
GAS6 growth arrest-specific 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA6 GATA binding protein 6
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GLO1 glyoxalase I
GLS2 glutaminase 2 (liver, mitochondrial)
GLYAT glycine-N-acyltransferase
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPER1 G protein-coupled estrogen receptor 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRAMD4 GRAM domain containing 4
GREM1 gremlin 1, DAN family BMP antagonist
GRID2 glutamate receptor, ionotropic, delta 2
GRK5 G protein-coupled receptor kinase 5
GRM4 glutamate receptor, metabotropic 4
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HAX1 HCLS1 associated protein X-1
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HIPK3 homeodomain interacting protein kinase 3
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMGN5 high mobility group nucleosome binding domain 5
HNRNPK heterogeneous nuclear ribonucleoprotein K
HOXA5 homeobox A5
HPN hepsin
HRK harakiri, BCL2 interacting protein
HS1BP3 HCLS1 binding protein 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTRA1 HtrA serine peptidase 1
HTRA2 HtrA serine peptidase 2
HTRA4 HtrA serine peptidase 4
HYPK huntingtin interacting protein K
IAPP islet amyloid polypeptide
IER3 immediate early response 3
IER3IP1 immediate early response 3 interacting protein 1
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFT57 intraflagellar transport 57
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL31RA interleukin 31 receptor A
IL4 interleukin 4
IL6 interleukin 6
IL6ST interleukin 6 signal transducer
IL7 interleukin 7
ING3 inhibitor of growth family, member 3
ING4 inhibitor of growth family, member 4
ING5 inhibitor of growth family, member 5
IP6K2 inositol hexakisphosphate kinase 2
IRF3 interferon regulatory factor 3
IRF5 interferon regulatory factor 5
ITCH itchy E3 ubiquitin protein ligase
ITGA6 integrin, alpha 6
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JMY junction mediating and regulatory protein, p53 cofactor
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KHDC3L KH domain containing 3-like, subcortical maternal complex member
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIF14 kinesin family member 14
KLF11 Kruppel-like factor 11
KLHL20 kelch-like family member 20
KNG1 kininogen 1
KRT18 keratin 18, type I
LACRT lacritin
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LCMT1 leucine carboxyl methyltransferase 1
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC102724652 alpha-crystallin A chain
LONP1 lon peptidase 1, mitochondrial
LRP2 low density lipoprotein receptor-related protein 2
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LTF lactotransferrin
LTK leukocyte receptor tyrosine kinase
MADD MAP-kinase activating death domain
MAGEA4 melanoma antigen family A4
MAGED1 melanoma antigen family D1
MALT1 MALT1 paracaspase
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MBD4 methyl-CpG binding domain protein 4
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEAF6 MYST/Esa1-associated factor 6
MED12 mediator complex subunit 12
MEF2C myocyte enhancer factor 2C
MELK maternal embryonic leucine zipper kinase
MGMT O-6-methylguanine-DNA methyltransferase
MIEN1 migration and invasion enhancer 1
MINDY4 MINDY lysine 48 deubiquitinase 4
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MOAP1 modulator of apoptosis 1
MORF4L1 mortality factor 4 like 1
MORF4L2 mortality factor 4 like 2
MPO myeloperoxidase
MRE11 MRE11 homolog, double strand break repair nuclease
MRGBP MRG/MORF4L binding protein
MTCH1 mitochondrial carrier 1
MTCH2 mitochondrial carrier 2
MTDH metadherin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYDGF myeloid-derived growth factor
MYO18A myosin XVIIIA
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
NAE1 NEDD8 activating enzyme E1 subunit 1
NAIP NLR family, apoptosis inhibitory protein
NCKAP1L NCK-associated protein 1-like
NEURL1 neuralized E3 ubiquitin protein ligase 1
NEUROD1 neuronal differentiation 1
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NIBAN2 niban apoptosis regulator 2
NKX2-5 NK2 homeobox 5
NKX2-6 NK2 homeobox 6
NLRC4 NLR family, CARD domain containing 4
NLRP2B NLR family pyrin domain containing 2B
NLRP3 NLR family, pyrin domain containing 3
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOP53 NOP53 ribosome biogenesis factor
NOTCH2 notch 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTSR1 neurotensin receptor 1 (high affinity)
NUAK2 NUAK family, SNF1-like kinase, 2
NUGGC nuclear GTPase, germinal center associated
NUP62 nucleoporin 62kDa
NUPR1 nuclear protein, transcriptional regulator, 1
OLFM1 olfactomedin 1
OMA1 OMA1 zinc metallopeptidase
OPN3 opsin 3
OSR1 odd-skipped related transciption factor 1
PA2G4 proliferation-associated 2G4, 38kDa
PAGE4 P antigen family, member 4 (prostate associated)
PANO1 proapoptotic nucleolar protein 1
PARK7 parkinson protein 7
PAWR PRKC, apoptosis, WT1, regulator
PAX2 paired box 2
PAX7 paired box 7
PAX8 paired box 8
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD10 programmed cell death 10
PDCD2 programmed cell death 2
PDCD5 programmed cell death 5
PDCD6 programmed cell death 6
PDPN podoplanin
PHB1 prohibitin 1
PHB2 prohibitin 2
PHIP pleckstrin homology domain interacting protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA3 pleckstrin homology-like domain, family A, member 3
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIDD1 p53-induced death domain protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
PINK1 PTEN induced putative kinase 1
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKN2 protein kinase N2
PLAUR plasminogen activator, urokinase receptor
PLEKHN1 pleckstrin homology domain containing, family N member 1
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
PLK5 polo-like kinase 5
PLSCR3 phospholipid scramblase 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA1 paraneoplastic Ma antigen 1
PNMA2 paraneoplastic Ma antigen 2
PNMA3 paraneoplastic Ma antigen 3
PNMA5 paraneoplastic Ma antigen family member 5
POTEF POTE ankyrin domain family, member F
POU3F3 POU class 3 homeobox 3
POU4F1 POU class 4 homeobox 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPID peptidylprolyl isomerase D
PPIF peptidylprolyl isomerase F
PPT1 palmitoyl-protein thioesterase 1
PRAME preferentially expressed antigen in melanoma
PRAP1 proline-rich acidic protein 1
PRDM9 PR domain containing 9
PRDX2 peroxiredoxin 2
PRDX3 peroxiredoxin 3
PRDX5 peroxiredoxin 5
PRELID1 PRELI domain containing 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKN parkin RBR E3 ubiquitin protein ligase
PRLR prolactin receptor
PRMT2 protein arginine methyltransferase 2
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROK2 prokineticin 2
PRPF38B pre-mRNA processing factor 38B
PRR5 proline rich 5 (renal)
PRR7 proline rich 7 (synaptic)
PSEN1 presenilin 1
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTMA prothymosin, alpha
PTMS parathymosin
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPRA protein tyrosine phosphatase, receptor type, A
PYCARD PYD and CARD domain containing
QRICH1 glutamine-rich 1
RACK1 receptor for activated C kinase 1
RARG retinoic acid receptor, gamma
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM25 RNA binding motif protein 25
RBM5 RNA binding motif protein 5
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REST RE1-silencing transcription factor
RHBDD1 rhomboid domain containing 1
RHOB ras homolog family member B
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE3 ribonuclease, RNase A family, 3
RNF122 ring finger protein 122
RNF144B ring finger protein 144B
RNF157 ring finger protein 157
RNPS1 RNA binding protein S1, serine-rich domain
RPL15 ribosomal protein L15
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RRP1B ribosomal RNA processing 1B
RSL1D1 ribosomal L1 domain containing 1
RTKN rhotekin
RTN4 reticulon 4
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
RYBP RING1 and YY1 binding protein
S100A9 S100 calcium binding protein A9
SAP18 Sin3A-associated protein, 18kDa
SAV1 salvador family WW domain containing protein 1
SCIN scinderin
SCRIB scribbled planar cell polarity protein
SCX scleraxis basic helix-loop-helix transcription factor
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEPTIN4 septin 4
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SH3RF1 SH3 domain containing ring finger 1
SH3RF2 SH3 domain containing ring finger 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SIGMAR1 sigma non-opioid intracellular receptor 1
SIRT1 sirtuin 1
SIX4 SIX homeobox 4
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLIT2 slit homolog 2 (Drosophila)
SLK STE20-like kinase
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS2 suppressor of cytokine signaling 2
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SON SON DNA binding protein
SOS1 son of sevenless homolog 1 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SPDEF SAM pointed domain containing ETS transcription factor
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPRY2 sprouty homolog 2 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STIL SCL/TAL1 interrupting locus
STK17A serine/threonine kinase 17a
STK17B serine/threonine kinase 17b
STK24 serine/threonine kinase 24
STK26 serine/threonine protein kinase 26
STK4 serine/threonine kinase 4
STPG1 sperm-tail PG-rich repeat containing 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SYNGAP1 synaptic Ras GTPase activating protein 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TANK TRAF family member-associated NFKB activator
TARDBP TAR DNA binding protein
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TBX3 T-box 3
TCIM transcriptional and immune response regulator
TCTN3 tectonic family member 3
TEK TEK tyrosine kinase, endothelial
TENT5B terminal nucleotidyltransferase 5B
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TFRC transferrin receptor
TGFB3 transforming growth factor, beta 3
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TJP1 tight junction protein 1
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMBIM6 transmembrane BAX inhibitor motif containing 6
TMC8 transmembrane channel-like 8
TMEM14A transmembrane protein 14A
TMEM196 transmembrane protein 196
TMIGD1 transmembrane and immunoglobulin domain containing 1
TNF tumor necrosis factor
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOMM70 translocase of outer mitochondrial membrane 70
TOP2A topoisomerase (DNA) II alpha 170kDa
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TPT1 tumor protein, translationally-controlled 1
TRADD TNFRSF1A-associated via death domain
TRIAP1 TP53 regulated inhibitor of apoptosis 1
TRIM2 tripartite motif containing 2
TRIM24 tripartite motif containing 24
TRIM35 tripartite motif containing 35
TRRAP transformation/transcription domain-associated protein
TSC22D1 TSC22 domain family, member 1
TSLP thymic stromal lymphopoietin
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum)
UBB ubiquitin B
UBD ubiquitin D
UBE2Z ubiquitin-conjugating enzyme E2Z
UFM1 ubiquitin-fold modifier 1
UNC13B unc-13 homolog B (C. elegans)
USP17L1 ubiquitin specific peptidase 17-like family member 1
USP17L10 ubiquitin specific peptidase 17-like family member 10
USP17L11 ubiquitin specific peptidase 17-like family member 11
USP17L12 ubiquitin specific peptidase 17-like family member 12
USP17L13 ubiquitin specific peptidase 17-like family member 13
USP17L15 ubiquitin specific peptidase 17-like family member 15
USP17L17 ubiquitin specific peptidase 17-like family member 17
USP17L18 ubiquitin specific peptidase 17-like family member 18
USP17L19 ubiquitin specific peptidase 17-like family member 19
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP17L20 ubiquitin specific peptidase 17-like family member 20
USP17L21 ubiquitin specific peptidase 17-like family member 21
USP17L22 ubiquitin specific peptidase 17-like family member 22
USP17L24 ubiquitin specific peptidase 17-like family member 24
USP17L3 ubiquitin specific peptidase 17-like family member 3
USP17L4 ubiquitin specific peptidase 17-like family member 4
USP17L5 ubiquitin specific peptidase 17-like family member 5
USP17L7 ubiquitin specific peptidase 17-like family member 7
USP17L8 ubiquitin specific peptidase 17-like family member 8
USP27X ubiquitin specific peptidase 27, X-linked
USP36 ubiquitin specific peptidase 36
USP42 ubiquitin specific peptidase 42
UTP11 UTP11 small subunit processome component
UXT ubiquitously-expressed, prefoldin-like chaperone
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VEGFB vascular endothelial growth factor B
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
VTCN1 V-set domain containing T cell activation inhibitor 1
WDR73 WD repeat domain 73
WFS1 Wolfram syndrome 1 (wolframin)
WNK3 WNK lysine deficient protein kinase 3
WNT1 wingless-type MMTV integration site family, member 1
WNT10B wingless-type MMTV integration site family, member 10B
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YEATS4 YEATS domain containing 4
YME1L1 YME1-like 1 ATPase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBP1 Z-DNA binding protein 1
ZBTB7A zinc finger and BTB domain containing 7A
ZFAND6 zinc finger, AN1-type domain 6
ZNF16 zinc finger protein 16
ZNF268 zinc finger protein 268
ZNF622 zinc finger protein 622
ZNF830 zinc finger protein 830