regulation of bone resorption Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). (Gene Ontology, GO_0045124)
External Link http://amigo.geneontology.org/amigo/term/GO:0045124
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Genes

31 genes participating in the regulation of bone resorption biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
BGLAP bone gamma-carboxyglutamate (gla) protein
CALCA calcitonin-related polypeptide alpha
CARTPT CART prepropeptide
CSF1R colony stimulating factor 1 receptor
CXXC1 CXXC finger protein 1
DCSTAMP dendrocyte expressed seven transmembrane protein
DEF8 differentially expressed in FDCP 8 homolog (mouse)
GPR137 G protein-coupled receptor 137
GPR137B G protein-coupled receptor 137B
IL6 interleukin 6
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
MC4R melanocortin 4 receptor
NF1 neurofibromin 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PRKCA protein kinase C, alpha
RUFY4 RUN and FYVE domain containing 4
S1PR1 sphingosine-1-phosphate receptor 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC4A2 solute carrier family 4 (anion exchanger), member 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TMEM119 transmembrane protein 119
TMEM64 transmembrane protein 64
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
UBASH3B ubiquitin associated and SH3 domain containing B