regulation of canonical Wnt signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. (Gene Ontology, GO_0060828)
External Link http://amigo.geneontology.org/amigo/term/GO_0060828
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Genes

208 genes participating in the regulation of canonical Wnt signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
AMER1 APC membrane recruitment protein 1
AMER2 APC membrane recruitment protein 2
AMER3 APC membrane recruitment protein 3
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANKRD6 ankyrin repeat domain 6
APC adenomatous polyposis coli
APC2 adenomatosis polyposis coli 2
APOE apolipoprotein E
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
AXIN1 axin 1
AXIN2 axin 2
BAMBI BMP and activin membrane-bound inhibitor
BICC1 BicC family RNA binding protein 1
BIRC8 baculoviral IAP repeat containing 8
BMP2 bone morphogenetic protein 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPRIN2 caprin family member 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCAR2 cell cycle and apoptosis regulator 2
CCDC88C coiled-coil domain containing 88C
CCL14 chemokine (C-C motif) ligand 14
CCNY cyclin Y
CCNYL1 cyclin Y-like 1
CCNYL2 cyclin Y-like 2, pseudogene
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK14 cyclin-dependent kinase 14
CHD8 chromodomain helicase DNA binding protein 8
COL1A1 collagen, type I, alpha 1
CSNK1A1 casein kinase 1, alpha 1
CSNK1A1L casein kinase 1, alpha 1-like
CSNK1D casein kinase 1, delta
CSNK1E casein kinase 1, epsilon
CSNK1G1 casein kinase 1, gamma 1
CSNK1G2 casein kinase 1, gamma 2
CSNK1G3 casein kinase 1, gamma 3
CTNND1 catenin (cadherin-associated protein), delta 1
CTNND2 catenin (cadherin-associated protein), delta 2
CYLD cylindromatosis (turban tumor syndrome)
DAAM2 dishevelled associated activator of morphogenesis 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DACT3 dishevelled-binding antagonist of beta-catenin 3
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DKK4 dickkopf WNT signaling pathway inhibitor 4
DKKL1 dickkopf-like 1
DRAXIN dorsal inhibitory axon guidance protein
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EMD emerin
FAM53B family with sequence similarity 53, member B
FGF10 fibroblast growth factor 10
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FRMD8 FERM domain containing 8
FRMD8P1 FERM domain containing 8 pseudogene 1
FRZB frizzled-related protein
FUZ fuzzy planar cell polarity protein
FZD6 frizzled class receptor 6
FZD7 frizzled class receptor 7
FZD9 frizzled class receptor 9
GID8 GID complex subunit 8
GLI1 GLI family zinc finger 1
GLI3 GLI family zinc finger 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPC3 glypican 3
GPC5 glypican 5
GPRC5B G protein-coupled receptor, class C, group 5, member B
GREM1 gremlin 1, DAN family BMP antagonist
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSKIP GSK3B interacting protein
HDAC1 histone deacetylase 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HHEX hematopoietically expressed homeobox
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IGFBP6 insulin-like growth factor binding protein 6
ILK integrin-linked kinase
INVS inversin
JADE1 jade family PHD finger 1
JRK Jrk homolog (mouse)
JUP junction plakoglobin
KANK1 KN motif and ankyrin repeat domains 1
KREMEN1 kringle containing transmembrane protein 1
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LGR6 leucine-rich repeat containing G protein-coupled receptor 6
LIMD1 LIM domains containing 1
LMBR1L limb development membrane protein 1-like
LOC102724928 putative cyclin-Y-like protein 3
LRP4 low density lipoprotein receptor-related protein 4
LRRK1 leucine-rich repeat kinase 1
LRRK2 leucine-rich repeat kinase 2
LYPD6 LY6/PLAUR domain containing 6
LZTS2 leucine zipper, putative tumor suppressor 2
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MCC mutated in colorectal cancers
MDK midkine (neurite growth-promoting factor 2)
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MRPS12 mitochondrial ribosomal protein S12
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKD1 naked cuticle homolog 1 (Drosophila)
NKD2 naked cuticle homolog 2 (Drosophila)
NKX2-5 NK2 homeobox 5
NOG noggin
NPHP3 nephronophthisis 3 (adolescent)
NPHP4 nephronophthisis 4
NRARP NOTCH-regulated ankyrin repeat protein
OTUD5 OTU deubiquitinase 5
OTULIN OTU deubiquitinase with linear linkage specificity
PARK2 parkin RBR E3 ubiquitin protein ligase
PFDN5 prefoldin subunit 5
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRDM15 PR domain containing 15
PRICKLE1 prickle homolog 1 (Drosophila)
PSEN1 presenilin 1
PTK7 protein tyrosine kinase 7 (inactive)
PTPRO protein tyrosine phosphatase, receptor type, O
PTPRU protein tyrosine phosphatase, receptor type, U
RBMS3 RNA binding motif, single stranded interacting protein 3
RBX1 ring-box 1, E3 ubiquitin protein ligase
RNF14 ring finger protein 14
RNF146 ring finger protein 146
RNF220 ring finger protein 220
RSPO1 R-spondin 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SCEL sciellin
SDHAF2 succinate dehydrogenase complex assembly factor 2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SFRP4 secreted frizzled-related protein 4
SFRP5 secreted frizzled-related protein 5
SHISA6 shisa family member 6
SIAH2 siah E3 ubiquitin protein ligase 2
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SNAI2 snail family zinc finger 2
SOST sclerostin
SOX13 SRY (sex determining region Y)-box 13
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SOX4 SRY (sex determining region Y)-box 4
SOX7 SRY (sex determining region Y)-box 7
SOX9 SRY (sex determining region Y)-box 9
STK11 serine/threonine kinase 11
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TBL1X transducin (beta)-like 1X-linked
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE2 transducin-like enhancer of split 2
TLE3 transducin-like enhancer of split 3
TLE4 transducin-like enhancer of split 4
TLE5 TLE family member 5, transcriptional modulator
TLE6 transducin-like enhancer of split 6
TLE7 TLE family member 7
TMEM131L transmembrane 131 like
TMEM170B transmembrane protein 170B
TMEM198 transmembrane protein 198
TMEM64 transmembrane protein 64
TMEM88 transmembrane protein 88
TMEM88B transmembrane protein 88B
TMEM9 transmembrane protein 9
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPBG trophoblast glycoprotein
TPBGL trophoblast glycoprotein-like
TRPM4 transient receptor potential cation channel, subfamily M, member 4
UBAC2 UBA domain containing 2
UBE2B ubiquitin-conjugating enzyme E2B
UBR5 ubiquitin protein ligase E3 component n-recognin 5
USP34 ubiquitin specific peptidase 34
USP47 ubiquitin specific peptidase 47
USP8 ubiquitin specific peptidase 8
VCP valosin containing protein
WLS wntless Wnt ligand secretion mediator
WNK1 WNK lysine deficient protein kinase 1
WNK2 WNK lysine deficient protein kinase 2
WNT11 wingless-type MMTV integration site family, member 11
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
WWTR1 WW domain containing transcription regulator 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZBED3 zinc finger, BED-type containing 3
ZEB2 zinc finger E-box binding homeobox 2
ZNF703 zinc finger protein 703
ZNRF3 zinc and ring finger 3