regulation of epithelial to mesenchymal transition Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. (Gene Ontology, GO_0010717)
External Link http://amigo.geneontology.org/amigo/term/GO:0010717
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Genes

92 genes participating in the regulation of epithelial to mesenchymal transition biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
ADIPOR1 adiponectin receptor 1
AGXT alanine-glyoxylate aminotransferase
ALX1 ALX homeobox 1
APLF aprataxin and PNKP like factor
AXIN2 axin 2
BAMBI BMP and activin membrane-bound inhibitor
BCL9L B-cell CLL/lymphoma 9-like
BMP2 bone morphogenetic protein 2
BMP5 bone morphogenetic protein 5
CLASP1 cytoplasmic linker associated protein 1
CLASP2 cytoplasmic linker associated protein 2
COL1A1 collagen, type I, alpha 1
CRB2 crumbs family member 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DAB2IP DAB2 interacting protein
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DSG2 desmoglein 2
EFNA1 ephrin-A1
ELL3 elongation factor RNA polymerase II-like 3
EPHA3 EPH receptor A3
EPHA4 EPH receptor A4
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FBXO11 F-box protein 11
FERMT2 fermitin family member 2
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXC1 forkhead box C1
GATA3 GATA binding protein 3
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GLIPR2 GLI pathogenesis-related 2
GREM1 gremlin 1, DAN family BMP antagonist
GSK3B glycogen synthase kinase 3 beta
HPN hepsin
IL17RD interleukin 17 receptor D
IL1B interleukin 1, beta
IL6 interleukin 6
KAT8 K(lysine) acetyltransferase 8
KDM1A lysine (K)-specific demethylase 1A
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEF1 lymphoid enhancer-binding factor 1
LOXL2 lysyl oxidase-like 2
LRG1 leucine-rich alpha-2-glycoprotein 1
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MARK1 MAP/microtubule affinity-regulating kinase 1
MCRIP1 MAPK regulated corepressor interacting protein 1
MDK midkine (neurite growth-promoting factor 2)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NKX2-1 NK2 homeobox 1
OLFM1 olfactomedin 1
OVOL2 ovo-like zinc finger 2
PDPN podoplanin
PHLDB1 pleckstrin homology-like domain, family B, member 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
QKI QKI, KH domain containing, RNA binding
RGCC regulator of cell cycle
SDCBP syndecan binding protein (syntenin)
SDHAF2 succinate dehydrogenase complex assembly factor 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SNAI1 snail family zinc finger 1
SPRED1 sprouty-related, EVH1 domain containing 1
SPRED2 sprouty-related, EVH1 domain containing 2
SPRED3 sprouty-related, EVH1 domain containing 3
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
TBX5 T-box 5
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIAM1 T-cell lymphoma invasion and metastasis 1
TNXB tenascin XB
TWIST1 twist family bHLH transcription factor 1
USF3 upstream transcription factor family member 3
VASN vasorin
WWTR1 WW domain containing transcription regulator 1
ZNF703 zinc finger protein 703
ZNF750 zinc finger protein 750