regulation of extrinsic apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway. (Gene Ontology, GO_2001236)
External Link http://amigo.geneontology.org/amigo/term/GO:2001236
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Genes

66 genes participating in the regulation of extrinsic apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ACVR1 activin A receptor, type I
AGTR2 angiotensin II receptor, type 2
AGXT alanine-glyoxylate aminotransferase
APP amyloid beta (A4) precursor protein
AREG amphiregulin
BCL10 B-cell CLL/lymphoma 10
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BID BH3 interacting domain death agonist
BIRC6 baculoviral IAP repeat containing 6
BMP4 bone morphogenetic protein 4
CAV1 caveolin 1, caveolae protein, 22kDa
CD40LG CD40 ligand
CFLAR CASP8 and FADD-like apoptosis regulator
CYLD cylindromatosis (turban tumor syndrome)
DEDD2 death effector domain containing 2
DEPTOR DEP domain containing MTOR-interacting protein
FADD Fas (TNFRSF6)-associated via death domain
FASLG Fas ligand (TNF superfamily, member 6)
FEM1B fem-1 homolog b (C. elegans)
G0S2 G0/G1 switch 2
GPER1 G protein-coupled estrogen receptor 1
GSTP1 glutathione S-transferase pi 1
HYAL2 hyaluronoglucosaminidase 2
IGF1 insulin-like growth factor 1 (somatomedin C)
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
LGALS3 lectin, galactoside-binding, soluble, 3
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MADD MAP-kinase activating death domain
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
PARK7 parkinson protein 7
PELI3 pellino E3 ubiquitin protein ligase family member 3
PHIP pleckstrin homology domain interacting protein
PKN2 protein kinase N2
PML promyelocytic leukemia
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PYCARD PYD and CARD domain containing
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SCG2 secretogranin II
SH3RF1 SH3 domain containing ring finger 1
SIAH2 siah E3 ubiquitin protein ligase 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SP100 SP100 nuclear antigen
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STX4 syntaxin 4
TANK TRAF family member-associated NFKB activator
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TMC8 transmembrane channel-like 8
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRAF1 TNF receptor-associated factor 1
WWOX WW domain containing oxidoreductase
ZMYND11 zinc finger, MYND-type containing 11