regulation of innate immune response Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. (Gene Ontology, GO_0045088)
External Link http://amigo.geneontology.org/amigo/term/GO_0045088
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Genes

79 genes participating in the regulation of innate immune response biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AKIRIN2 akirin 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
APLP2 amyloid beta (A4) precursor-like protein 2
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ATG12 autophagy related 12
ATG5 autophagy related 5
AURKB aurora kinase B
BANF1 barrier to autointegration factor 1
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
CACTIN cactin, spliceosome C complex subunit
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD1D CD1d molecule
CDC37 cell division cycle 37
CEP63 centrosomal protein 63kDa
CFH complement factor H
CGAS cyclic GMP-AMP synthase
CXORF21 chromosome X open reading frame 21
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9
DTX4 deltex 4, E3 ubiquitin ligase
ERAP1 endoplasmic reticulum aminopeptidase 1
EREG epiregulin
FADD Fas (TNFRSF6)-associated via death domain
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGR FGR proto-oncogene, Src family tyrosine kinase
FPR2 formyl peptide receptor 2
GBP5 guanylate binding protein 5
HLA-E major histocompatibility complex, class I, E
IFI16 interferon, gamma-inducible protein 16
IFI35 interferon-induced protein 35
IFNB1 interferon, beta 1, fibroblast
IFNK interferon, kappa
IRAK3 interleukin-1 receptor-associated kinase 3
IRF1 interferon regulatory factor 1
IRG1 immunoresponsive 1 homolog (mouse)
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYAR Ly1 antibody reactive
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1C myosin IC
N4BP1 NEDD4 binding protein 1
NFE2L2 nuclear factor, erythroid 2-like 2
NLRC3 NLR family, CARD domain containing 3
PARP1 poly (ADP-ribose) polymerase 1
PARP9 poly (ADP-ribose) polymerase family, member 9
PCBP2 poly(rC) binding protein 2
PLSCR1 phospholipid scramblase 1
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD)
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD)
PPP6C protein phosphatase 6, catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RIOK3 RIO kinase 3
RNF135 ring finger protein 135
RNF185 ring finger protein 185
SAMHD1 SAM domain and HD domain 1
SH2D1B SH2 domain containing 1B
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TKFC triokinase/FMN cyclase
TLR8 toll-like receptor 8
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAFD1 TRAF-type zinc finger domain containing 1
TREM2 triggering receptor expressed on myeloid cells 2
TREX1 three prime repair exonuclease 1
TRIM21 tripartite motif containing 21
TRIM56 tripartite motif containing 56
TYRO3 TYRO3 protein tyrosine kinase
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZDHHC18 zinc finger, DHHC-type containing 18