regulation of insulin secretion Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the regulated release of insulin. (Gene Ontology, GO_0050796)
External Link http://amigo.geneontology.org/amigo/term/GO_0050796
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Genes

88 genes participating in the regulation of insulin secretion biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AACS acetoacetyl-CoA synthetase
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACSL4 acyl-CoA synthetase long-chain family member 4
ADCY5 adenylate cyclase 5
ADCY8 adenylate cyclase 8 (brain)
ADRA2A adrenoceptor alpha 2A
ALOX5 arachidonate 5-lipoxygenase
ARNTL aryl hydrocarbon receptor nuclear translocator-like
BAD BCL2-associated agonist of cell death
BLK BLK proto-oncogene, Src family tyrosine kinase
BMP8A bone morphogenetic protein 8a
BRSK2 BR serine/threonine kinase 2
CAPN10 calpain 10
CCL5 chemokine (C-C motif) ligand 5
CCN3 cellular communication network factor 3
CDK16 cyclin-dependent kinase 16
CELA2A chymotrypsin-like elastase family, member 2A
CHGA chromogranin A
CLOCK clock circadian regulator
DOC2B double C2-like domains, beta
EFNA5 ephrin-A5
EIPR1 EARP complex and GARP complex interacting protein 1
ENSA endosulfine alpha
EPHA5 EPH receptor A5
FAM3D family with sequence similarity 3, member D
FFAR1 free fatty acid receptor 1
FOXA2 forkhead box A2
FOXO1 forkhead box O1
G6PC2 glucose-6-phosphatase, catalytic, 2
GCG glucagon
GCK glucokinase (hexokinase 4)
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GIPR gastric inhibitory polypeptide receptor
GLUD1 glutamate dehydrogenase 1
GPER1 G protein-coupled estrogen receptor 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HNF4A hepatocyte nuclear factor 4, alpha
IFNG interferon, gamma
IL1B interleukin 1, beta
IL6 interleukin 6
INHBB inhibin, beta B
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ISL1 ISL LIM homeobox 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
LRP5 low density lipoprotein receptor-related protein 5
LRRC8A leucine rich repeat containing 8 family, member A
MCU mitochondrial calcium uniporter
MIDN midnolin
MTNR1B melatonin receptor 1B
MYRIP myosin VIIA and Rab interacting protein
NEUROD1 neuronal differentiation 1
NLGN2 neuroligin 2
NNAT neuronatin
NOS2 nitric oxide synthase 2, inducible
NR1D1 nuclear receptor subfamily 1, group D, member 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
PARK2 parkin RBR E3 ubiquitin protein ligase
PDX1 pancreatic and duodenal homeobox 1
PER2 period circadian clock 2
PICK1 protein interacting with PRKCA 1
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
REST RE1-silencing transcription factor
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RFX6 regulatory factor X, 6
SFRP1 secreted frizzled-related protein 1
SIRT4 sirtuin 4
SIRT6 sirtuin 6
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC30A8 solute carrier family 30 (zinc transporter), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SSTR5 somatostatin receptor 5
STX1A syntaxin 1A (brain)
STXBP4 syntaxin binding protein 4
SYT7 synaptotagmin VII
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TM7SF3 transmembrane 7 superfamily member 3
TNF tumor necrosis factor
TRH thyrotropin-releasing hormone
UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2