regulation of intrinsic apoptotic signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway. (Gene Ontology, GO_2001242)
External Link http://amigo.geneontology.org/amigo/term/GO:2001242
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Genes

47 genes participating in the regulation of intrinsic apoptotic signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCAP31 B-cell receptor-associated protein 31
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCLAF1 BCL2-associated transcription factor 1
BECN1 beclin 1, autophagy related
BID BH3 interacting domain death agonist
BOK BCL2-related ovarian killer
CAV1 caveolin 1, caveolae protein, 22kDa
CLU clusterin
CYLD cylindromatosis (turban tumor syndrome)
DAPK2 death-associated protein kinase 2
DDIT3 DNA-damage-inducible transcript 3
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GSDME gasdermin E
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
MMP9 matrix metallopeptidase 9
NKX3-1 NK3 homeobox 1
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NUPR1 nuclear protein, transcriptional regulator, 1
P4HB prolyl 4-hydroxylase, beta polypeptide
PINK1 PTEN induced putative kinase 1
PLAUR plasminogen activator, urokinase receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPIF peptidylprolyl isomerase F
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
PYCARD PYD and CARD domain containing
RACK1 receptor for activated C kinase 1
RTKN2 rhotekin 2
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SEPTIN4 septin 4
SGMS1 sphingomyelin synthase 1
SIAH1 siah E3 ubiquitin protein ligase 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STYXL1 serine/threonine/tyrosine interacting-like 1
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TP53 tumor protein p53
UBQLN1 ubiquilin 1
URI1 URI1, prefoldin-like chaperone