regulation of macroautophagy Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of macroautophagy. (Gene Ontology, GO_0016241)
External Link http://amigo.geneontology.org/amigo/term/GO:0016241
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Genes

107 genes participating in the regulation of macroautophagy biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ATG12 autophagy related 12
ATG14 autophagy related 14
ATG5 autophagy related 5
ATP13A2 ATPase type 13A2
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B1 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1E2 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
BECN1 beclin 1, autophagy related
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
C9ORF72 chromosome 9 open reading frame 72
CAPN1 calpain 1, (mu/I) large subunit
CAPNS1 calpain, small subunit 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CLEC16A C-type lectin domain family 16, member A
CLN3 ceroid-lipofuscinosis, neuronal 3
CSNK2A2 casein kinase 2, alpha prime polypeptide
DCN decorin
DNM1L dynamin 1-like
ERN1 endoplasmic reticulum to nucleus signaling 1
EXOC1 exocyst complex component 1
EXOC4 exocyst complex component 4
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP8 FK506 binding protein 8, 38kDa
FZD5 frizzled class receptor 5
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GBA1 glucosylceramidase beta 1
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GPSM1 G-protein signaling modulator 1
GSK3A glycogen synthase kinase 3 alpha
HDAC6 histone deacetylase 6
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL4 interleukin 4
KDR kinase insert domain receptor
LACRT lacritin
LARP1 La ribonucleoprotein domain family, member 1
LRRK2 leucine-rich repeat kinase 2
LZTS1 leucine zipper, putative tumor suppressor 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK8 mitogen-activated protein kinase 8
MTMR9 myotubularin related protein 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NRBP2 nuclear receptor binding protein 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARL presenilin associated, rhomboid-like
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PINK1 PTEN induced putative kinase 1
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
QSOX1 quiescin Q6 sulfhydryl oxidase 1
RHEB Ras homolog enriched in brain
RUFY4 RUN and FYVE domain containing 4
SCOC short coiled-coil protein
SESN1 sestrin 1
SESN2 sestrin 2
SESN3 sestrin 3
SH3GLB1 SH3-domain GRB2-like endophilin B1
SIRT1 sirtuin 1
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8
SNX32 sorting nexin 32
SNX5 sorting nexin 5
SNX6 sorting nexin 6
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
STING1 stimulator of interferon response cGAMP interactor 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TBC1D25 TBC1 domain family, member 25
TBK1 TANK-binding kinase 1
TECPR1 tectonin beta-propeller repeat containing 1
TRIM13 tripartite motif containing 13
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
UBQLN1 ubiquilin 1
UBQLN2 ubiquilin 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ULK1 unc-51 like autophagy activating kinase 1
USP36 ubiquitin specific peptidase 36
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS26B vacuolar protein sorting 26 homolog B (S. pombe)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WAC WW domain containing adaptor with coiled-coil
WDR24 WD repeat domain 24