regulation of programmed cell death Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. (Gene Ontology, GO_0043067)
External Link http://amigo.geneontology.org/amigo/term/GO:0043067
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Genes

196 genes participating in the regulation of programmed cell death biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
ACTL6A actin-like 6A
ACTN1 actinin, alpha 1
ACTN2 actinin, alpha 2
ACTN3 actinin, alpha 3 (gene/pseudogene)
ACTN4 actinin, alpha 4
AGXT alanine-glyoxylate aminotransferase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
ALK anaplastic lymphoma receptor tyrosine kinase
ALPK2 alpha-kinase 2
AMIGO2 adhesion molecule with Ig-like domain 2
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
APAF1 apoptotic peptidase activating factor 1
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATM ATM serine/threonine kinase
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCL2L2 BCL2-like 2
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BEX2 brain expressed X-linked 2
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRD8 bromodomain containing 8
BRMS1L breast cancer metastasis-suppressor 1-like
CALR calreticulin
CASP6 caspase 6, apoptosis-related cysteine peptidase
CCNL1 cyclin L1
CCNL2 cyclin L2
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK5 cyclin-dependent kinase 5
CIDEA cell death-inducing DFFA-like effector a
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLU clusterin
CREB3L4 cAMP responsive element binding protein 3-like 4
CRYAB crystallin, alpha B
CTSB cathepsin B
CXCL10 chemokine (C-X-C motif) ligand 10
DAPK1 death-associated protein kinase 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DAXX death-domain associated protein
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DMAP1 DNA methyltransferase 1 associated protein 1
DPP8 dipeptidyl-peptidase 8
DPP9 dipeptidyl-peptidase 9
DYNAP dynactin associated protein
EP400 E1A binding protein p400
EPC1 enhancer of polycomb homolog 1 (Drosophila)
EPC2 enhancer of polycomb homolog 2 (Drosophila)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FASN fatty acid synthase
FBXO10 F-box protein 10
FBXO11 F-box protein 11
FLT3 fms-related tyrosine kinase 3
GAS1 growth arrest-specific 1
GLS2 glutaminase 2 (liver, mitochondrial)
HAX1 HCLS1 associated protein X-1
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HS1BP3 HCLS1 binding protein 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IFT57 intraflagellar transport 57
IKZF3 IKAROS family zinc finger 3 (Aiolos)
ING3 inhibitor of growth family, member 3
IRF3 interferon regulatory factor 3
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KANK2 KN motif and ankyrin repeat domains 2
KAT5 K(lysine) acetyltransferase 5
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LCMT1 leucine carboxyl methyltransferase 1
LGALS1 lectin, galactoside-binding, soluble, 1
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRK2 leucine-rich repeat kinase 2
MADD MAP-kinase activating death domain
MAGED1 melanoma antigen family D1
MALT1 MALT1 paracaspase
MAP3K20 mitogen-activated protein kinase kinase kinase 20
MARK4 MAP/microtubule affinity-regulating kinase 4
MBTD1 mbt domain containing 1
MCL1 myeloid cell leukemia 1
MEAF6 MYST/Esa1-associated factor 6
MECOM MDS1 and EVI1 complex locus
MOAP1 modulator of apoptosis 1
MORF4L1 mortality factor 4 like 1
MORF4L2 mortality factor 4 like 2
MRGBP MRG/MORF4L binding protein
NAE1 NEDD8 activating enzyme E1 subunit 1
NAIP NLR family, apoptosis inhibitory protein
NF2 neurofibromin 2 (merlin)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NME2 NME/NM23 nucleoside diphosphate kinase 2
NOP53 NOP53 ribosome biogenesis factor
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP62 nucleoporin 62kDa
PAX2 paired box 2
PAX8 paired box 8
PDCD5 programmed cell death 5
PEPD peptidase D
PHB1 prohibitin 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PINK1 PTEN induced putative kinase 1
PLK5 polo-like kinase 5
PLSCR3 phospholipid scramblase 3
POTEF POTE ankyrin domain family, member F
POU4F1 POU class 4 homeobox 1
POU4F2 POU class 4 homeobox 2
PRDX2 peroxiredoxin 2
PRKN parkin RBR E3 ubiquitin protein ligase
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RARG retinoic acid receptor, gamma
RBM25 RNA binding motif protein 25
REST RE1-silencing transcription factor
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RIPK3 receptor-interacting serine-threonine kinase 3
RNASE3 ribonuclease, RNase A family, 3
RPS3 ribosomal protein S3
RSL1D1 ribosomal L1 domain containing 1
RTKN rhotekin
RTN4 reticulon 4
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SEPTIN4 septin 4
SGK1 serum/glucocorticoid regulated kinase 1
SIRT1 sirtuin 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLK STE20-like kinase
SOX9 SRY (sex determining region Y)-box 9
STAT1 signal transducer and activator of transcription 1, 91kDa
STK26 serine/threonine protein kinase 26
TANK TRAF family member-associated NFKB activator
TARDBP TAR DNA binding protein
TGM2 transglutaminase 2
TIGAR TP53 induced glycolysis regulatory phosphatase
TM7SF3 transmembrane 7 superfamily member 3
TMEM109 transmembrane protein 109
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TOMM70 translocase of outer mitochondrial membrane 70
TOX3 TOX high mobility group box family member 3
TP53 tumor protein p53
TPT1 tumor protein, translationally-controlled 1
TRIM24 tripartite motif containing 24
TRRAP transformation/transcription domain-associated protein
TSC22D1 TSC22 domain family, member 1
USP17L1 ubiquitin specific peptidase 17-like family member 1
USP17L10 ubiquitin specific peptidase 17-like family member 10
USP17L11 ubiquitin specific peptidase 17-like family member 11
USP17L12 ubiquitin specific peptidase 17-like family member 12
USP17L13 ubiquitin specific peptidase 17-like family member 13
USP17L15 ubiquitin specific peptidase 17-like family member 15
USP17L17 ubiquitin specific peptidase 17-like family member 17
USP17L18 ubiquitin specific peptidase 17-like family member 18
USP17L19 ubiquitin specific peptidase 17-like family member 19
USP17L2 ubiquitin specific peptidase 17-like family member 2
USP17L20 ubiquitin specific peptidase 17-like family member 20
USP17L21 ubiquitin specific peptidase 17-like family member 21
USP17L22 ubiquitin specific peptidase 17-like family member 22
USP17L24 ubiquitin specific peptidase 17-like family member 24
USP17L3 ubiquitin specific peptidase 17-like family member 3
USP17L4 ubiquitin specific peptidase 17-like family member 4
USP17L5 ubiquitin specific peptidase 17-like family member 5
USP17L7 ubiquitin specific peptidase 17-like family member 7
USP17L8 ubiquitin specific peptidase 17-like family member 8
USP36 ubiquitin specific peptidase 36
USP42 ubiquitin specific peptidase 42
UXT ubiquitously-expressed, prefoldin-like chaperone
VCP valosin containing protein
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae)
WFS1 Wolfram syndrome 1 (wolframin)
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
YEATS4 YEATS domain containing 4
ZBTB7A zinc finger and BTB domain containing 7A
ZDHHC17 zinc finger, DHHC-type containing 17