regulation of proteasomal protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome. (Gene Ontology, GO_0061136)
External Link http://amigo.geneontology.org/amigo/term/GO:0061136
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Genes

57 genes participating in the regulation of proteasomal protein catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ALAD aminolevulinate dehydratase
APOE apolipoprotein E
ARAF A-Raf proto-oncogene, serine/threonine kinase
BAG2 BCL2-associated athanogene 2
COMMD1 copper metabolism (Murr1) domain containing 1
DAB2IP DAB2 interacting protein
DDRGK1 DDRGK domain containing 1
DESI2 desumoylating isopeptidase 2
DNAAF4 dynein axonemal assembly factor 4
ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator
F8A1 coagulation factor VIII-associated 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMR1 fragile X mental retardation 1
FOXF2 forkhead box F2
GABARAPL2 GABA(A) receptor-associated protein-like 2
GLMN glomulin, FKBP associated protein
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GPX1 glutathione peroxidase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
LAMP3 lysosomal-associated membrane protein 3
MARCHF7 membrane associated ring-CH-type finger 7
NEURL3 neuralized E3 ubiquitin protein ligase 3
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
NUPR1 nuclear protein, transcriptional regulator, 1
OPHN1 oligophrenin 1
OSBPL7 oxysterol binding protein-like 7
PINK1 PTEN induced putative kinase 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PRKCA protein kinase C, alpha
PRKCG protein kinase C, gamma
PRKN parkin RBR E3 ubiquitin protein ligase
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
PSME3IP1 proteasome activator subunit 3 interacting protein 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
RAD23A RAD23 homolog A (S. cerevisiae)
RAD23B RAD23 homolog B (S. cerevisiae)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
TMF1 TATA element modulatory factor 1
TMTC3 transmembrane and tetratricopeptide repeat containing 3
TREM2 triggering receptor expressed on myeloid cells 2
UBB ubiquitin B
UBQLN4 ubiquilin 4
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UFL1 UFM1-specific ligase 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
USP19 ubiquitin specific peptidase 19
XPO1 exportin 1
ZNF418 zinc finger protein 418