regulation of protein catabolic process Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. (Gene Ontology, GO_0042176)
External Link http://amigo.geneontology.org/amigo/term/GO:0042176
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Genes

130 genes participating in the regulation of protein catabolic process biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADGRB1 adhesion G protein-coupled receptor B1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AMER1 APC membrane recruitment protein 1
APOE apolipoprotein E
ASB11 ankyrin repeat and SOCS box containing 11, E3 ubiquitin protein ligase
ASB5 ankyrin repeat and SOCS box containing 5
ASB9 ankyrin repeat and SOCS box containing 9
ATG7 autophagy related 7
ATP13A2 ATPase type 13A2
ATRAID all-trans retinoic acid-induced differentiation factor
AXIN1 axin 1
AZIN1 antizyme inhibitor 1
AZIN2 antizyme inhibitor 2
BARD1 BRCA1 associated RING domain 1
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
CDK5RAP3 CDK5 regulatory subunit associated protein 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CENATAC centrosomal AT-AC splicing factor
CHEK2 checkpoint kinase 2
CHMP6 charged multivesicular body protein 6
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CREBRF CREB3 regulatory factor
CSNK2A2 casein kinase 2, alpha prime polypeptide
CSNK2A3 casein kinase 2, alpha 3 polypeptide
CTSA cathepsin A
CUL4A cullin 4A
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DAB2IP DAB2 interacting protein
DACT1 dishevelled-binding antagonist of beta-catenin 1
DAOA D-amino acid oxidase activator
DCAF1 DDB1 and CUL4 associated factor 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DNAAF4 dynein axonemal assembly factor 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGFR epidermal growth factor receptor
EGLN2 egl-9 family hypoxia-inducible factor 2
EZR ezrin
FAF1 Fas (TNFRSF6) associated factor 1
FLNA filamin A, alpha
FMN2 formin 2
FOXO1 forkhead box O1
FURIN furin (paired basic amino acid cleaving enzyme)
GFAP glial fibrillary acidic protein
GPC3 glypican 3
GPX1 glutathione peroxidase 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IDE insulin-degrading enzyme
INS insulin
IRAK3 interleukin-1 receptor-associated kinase 3
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MSN moesin
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NELL1 NEL-like 1 (chicken)
NKD1 naked cuticle homolog 1 (Drosophila)
NQO1 NAD(P)H dehydrogenase, quinone 1
NSF N-ethylmaleimide-sensitive factor
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15
OAZ1 ornithine decarboxylase antizyme 1
OAZ2 ornithine decarboxylase antizyme 2
OAZ3 ornithine decarboxylase antizyme 3
PDZD2 PDZ domain containing 2
PHB1 prohibitin 1
PHF20L1 PHD finger protein 20-like 1
PINK1 PTEN induced putative kinase 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLK2 polo-like kinase 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRICKLE1 prickle homolog 1 (Drosophila)
PRKCA protein kinase C, alpha
PRKCG protein kinase C, gamma
PRKN parkin RBR E3 ubiquitin protein ligase
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAB7A RAB7A, member RAS oncogene family
RBX1 ring-box 1, E3 ubiquitin protein ligase
RDX radixin
RGPD1 RANBP2-like and GRIP domain containing 1
RHBDD1 rhomboid domain containing 1
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RIC1 RAB6A GEF complex partner 1
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
SACK1D scaffolding CK1 anchoring protein D
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12
SF3B3 splicing factor 3b, subunit 3, 130kDa
SIRT2 sirtuin 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNF8 SNF8, ESCRT-II complex subunit
SNX12 sorting nexin 12
SNX3 sorting nexin 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
STX5 syntaxin 5
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM9 transmembrane protein 9
TMF1 TATA element modulatory factor 1
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TRIM32 tripartite motif containing 32
TRIM40 tripartite motif containing 40
TSPAN15 tetraspanin 15
TSPAN17 tetraspanin 17
TSPAN5 tetraspanin 5
UBB ubiquitin B
UBXN2A UBX domain protein 2A
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VCP valosin containing protein
VGLL4 vestigial-like family member 4
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WDR91 WD repeat domain 91
WNT5A wingless-type MMTV integration site family, member 5A
ZDHHC2 zinc finger, DHHC-type containing 2
ZNF268 zinc finger protein 268