regulation of proteolysis Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. (Gene Ontology, GO_0030162)
External Link http://amigo.geneontology.org/amigo/term/GO:0030162
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Genes

54 genes participating in the regulation of proteolysis biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ASPH aspartate beta-hydroxylase
AURKAIP1 aurora kinase A interacting protein 1
BAD BCL2-associated agonist of cell death
BAG6 BCL2-associated athanogene 6
BAK1 BCL2-antagonist/killer 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPN3 calpain 3, (p94)
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CST3 cystatin C
CST4 cystatin S
CSTA cystatin A (stefin A)
CSTB cystatin B (stefin B)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
FADD Fas (TNFRSF6)-associated via death domain
FBXW11 F-box and WD repeat domain containing 11
FGFR4 fibroblast growth factor receptor 4
GSAP gamma-secretase activating protein
HDAC2 histone deacetylase 2
HDAC6 histone deacetylase 6
IST1 increased sodium tolerance 1 homolog (yeast)
KNG1 kininogen 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PARL presenilin associated, rhomboid-like
PERP PERP, TP53 apoptosis effector
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
PRSS37 protease, serine, 37
RHOBTB3 Rho-related BTB domain containing 3
RNF139 ring finger protein 139
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SHH sonic hedgehog
SPOP speckle-type POZ protein
SPOPL speckle-type POZ protein-like
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TBC1D10A TBC1 domain family, member 10A
TM4SF20 transmembrane 4 L six family member 20
TRAF3 TNF receptor-associated factor 3
TRIM32 tripartite motif containing 32
TSPAN15 tetraspanin 15
TSPAN17 tetraspanin 17
TSPAN5 tetraspanin 5
TTF2 transcription termination factor, RNA polymerase II
UBXN2A UBX domain protein 2A