regulation of signal transduction Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the frequency, rate or extent of signal transduction. (Gene Ontology, GO_0009966)
External Link http://amigo.geneontology.org/amigo/term/GO:0009966
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Genes

212 genes participating in the regulation of signal transduction biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ACTRT1 actin-related protein T1
ACVR1 activin A receptor, type I
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
AFAP1 actin filament associated protein 1
ANKRD54 ankyrin repeat domain 54
APP amyloid beta (A4) precursor protein
C6ORF89 chromosome 6 open reading frame 89
CAV3 caveolin 3
CCNK cyclin K
CD177 CD177 molecule
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD46 CD46 molecule, complement regulatory protein
CD47 CD47 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD63 CD63 molecule
CD80 CD80 molecule
CDC42SE2 CDC42 small effector 2
CDK13 cyclin-dependent kinase 13
CDKN2AIP CDKN2A interacting protein
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
CLU clusterin
CLXN calaxin
CREBBP CREB binding protein
CRIPTO3 cripto, EGF-CFC family member 3
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSK c-src tyrosine kinase
CX3CL1 chemokine (C-X3-C motif) ligand 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2
DCDC2 doublecortin domain containing 2
DGKQ diacylglycerol kinase, theta 110kDa
DLL1 delta-like 1 (Drosophila)
DOK5 docking protein 5
DTNBP1 dystrobrevin binding protein 1
DTX1 deltex 1, E3 ubiquitin ligase
DYNLT1 dynein, light chain, Tctex-type 1
ERBB3 erb-b2 receptor tyrosine kinase 3
FBXL17 F-box and leucine-rich repeat protein 17
FFAR3 free fatty acid receptor 3
FGFR2 fibroblast growth factor receptor 2
FOXL1 forkhead box L1
FRMPD1 FERM and PDZ domain containing 1
FRRS1L ferric-chelate reductase 1-like
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
FUZ fuzzy planar cell polarity protein
FYN FYN proto-oncogene, Src family tyrosine kinase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GAS1 growth arrest-specific 1
GATA3 GATA binding protein 3
GDNF glial cell derived neurotrophic factor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GLI1 GLI family zinc finger 1
GLRX2 glutaredoxin 2
GNAS GNAS complex locus
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR158 G protein-coupled receptor 158
GRK1 G protein-coupled receptor kinase 1
GRK4 G protein-coupled receptor kinase 4
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GRK7 G protein-coupled receptor kinase 7
GSKIP GSK3B interacting protein
GUCA1ANB-GUCA1A GUCA1ANB-GUCA1A readthrough
GUCA1B guanylate cyclase activator 1B (retina)
GUCA1C guanylate cyclase activator 1C
HHIP hedgehog interacting protein
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HNF1A HNF1 homeobox A
HOMER1 homer scaffolding protein 1
HPCA hippocalcin
HPCAL1 hippocalcin-like 1
HPCAL4 hippocalcin like 4
IFT81 intraflagellar transport 81
IGFBP1 insulin-like growth factor binding protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IGFBP7 insulin-like growth factor binding protein 7
IGFBPL1 insulin-like growth factor binding protein-like 1
ILK integrin-linked kinase
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INTU inturned planar cell polarity protein
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK2 interleukin-1 receptor-associated kinase 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGB1BP1 integrin beta 1 binding protein 1
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNIP1 Kv channel interacting protein 1
KCNIP2 Kv channel interacting protein 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNIP4 Kv channel interacting protein 4
KCTD12 potassium channel tetramerization domain containing 12
KCTD16 potassium channel tetramerization domain containing 16
KCTD8 potassium channel tetramerization domain containing 8
KIF26A kinesin family member 26A
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LLGL2 lethal giant larvae homolog 2 (Drosophila)
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MDFI MyoD family inhibitor
MDFIC MyoD family inhibitor domain containing
MDFIC2 MyoD family inhibitor domain containing 2
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MGLL monoglyceride lipase
MPIG6B megakaryocyte and platelet inhibitory receptor G6b
MTCH1 mitochondrial carrier 1
MZB1 marginal zone B and B1 cell-specific protein
NCALD neurocalcin delta
NCAM1 neural cell adhesion molecule 1
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCLN nicalin
NCOA5 nuclear receptor coactivator 5
NCS1 neuronal calcium sensor 1
NLE1 notchless homolog 1 (Drosophila)
NLRP12 NLR family, pyrin domain containing 12
NOG noggin
NRP1 neuropilin 1
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
NUP62 nucleoporin 62kDa
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OTX2 orthodenticle homeobox 2
PGAP1 post-GPI attachment to proteins 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLSCR1 phospholipid scramblase 1
POFUT1 protein O-fucosyltransferase 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K
PPP6R1 protein phosphatase 6, regulatory subunit 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PPP6R3 protein phosphatase 6, regulatory subunit 3
PRAG1 PEAK1 related, kinase-activating pseudokinase 1
PRKD1 protein kinase D1
PRNP prion protein
PTCH1 patched 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PXDN peroxidasin
RCVRN recoverin
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RGS20 regulator of G-protein signaling 20
RGS3 regulator of G-protein signaling 3
RGS4 regulator of G-protein signaling 4
RGS5 regulator of G-protein signaling 5
RIC8B RIC8 guanine nucleotide exchange factor B
RORA RAR-related orphan receptor A
SAMD5 sterile alpha motif domain containing 5
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SASH3 SAM and SH3 domain containing 3
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SHARPIN SHANK-associated RH domain interactor
SIK2 salt-inducible kinase 2
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SNX3 sorting nexin 3
SOCS2 suppressor of cytokine signaling 2
SOCS5 suppressor of cytokine signaling 5
SP100 SP100 nuclear antigen
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF2 sterol regulatory element binding transcription factor 2
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites
STK11 serine/threonine kinase 11
STRN striatin, calmodulin binding protein
STRN4 striatin, calmodulin binding protein 4
SULF1 sulfatase 1
SYNJ2BP synaptojanin 2 binding protein
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM108 transmembrane protein 108
TMEM204 transmembrane protein 204
TMEM237 transmembrane protein 237
TRIM5 tripartite motif containing 5
TSC2 tuberous sclerosis 2
TSPAN15 tetraspanin 15
TSPAN32 tetraspanin 32
TSPEAR thrombospondin-type laminin G domain and EAR repeats
TSPYL2 TSPY-like 2
TULP3 tubby like protein 3
UBASH3B ubiquitin associated and SH3 domain containing B
UBTF upstream binding transcription factor, RNA polymerase I
UGCG UDP-glucose ceramide glucosyltransferase
USP20 ubiquitin specific peptidase 20
USP33 ubiquitin specific peptidase 33
VEPH1 ventricular zone expressed PH domain-containing 1
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VSNL1 visinin-like 1
VWA2 von Willebrand factor A domain containing 2
WDR11 WD repeat domain 11
YJEFN3 YjeF N-terminal domain containing 3
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZDHHC17 zinc finger, DHHC-type containing 17
ZDHHC3 zinc finger, DHHC-type containing 3
ZDHHC7 zinc finger, DHHC-type containing 7
ZFAND2B zinc finger, AN1-type domain 2B
ZIC1 Zic family member 1
ZMYND11 zinc finger, MYND-type containing 11