regulation of tumor necrosis factor-mediated signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor. (Gene Ontology, GO_0010803)
External Link http://amigo.geneontology.org/amigo/term/GO:0010803
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Genes

51 genes participating in the regulation of tumor necrosis factor-mediated signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
APOA1 apolipoprotein A-I
BIRC7 baculoviral IAP repeat containing 7
CARD16 caspase recruitment domain family, member 16
CARD8 caspase recruitment domain family, member 8
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC3 coiled-coil domain containing 3
CPNE1 copine I
CYLD cylindromatosis (turban tumor syndrome)
DICER1 dicer 1, ribonuclease type III
F2RL1 coagulation factor II (thrombin) receptor-like 1
GAS6 growth arrest-specific 6
GPS2 G protein pathway suppressor 2
GSTP1 glutathione S-transferase pi 1
H2BC11 H2B clustered histone 11
HIPK1 homeodomain interacting protein kinase 1
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
LAPTM5 lysosomal protein transmembrane 5
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MIB2 mindbomb E3 ubiquitin protein ligase 2
MMP8 matrix metallopeptidase 8
NAIP NLR family, apoptosis inhibitory protein
NLRP2B NLR family pyrin domain containing 2B
OTULIN OTU deubiquitinase with linear linkage specificity
PELI3 pellino E3 ubiquitin protein ligase family member 3
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKN parkin RBR E3 ubiquitin protein ligase
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PYCARD PYD and CARD domain containing
PYDC1 PYD (pyrin domain) containing 1
PYDC2 pyrin domain containing 2
RFFL ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
SHARPIN SHANK-associated RH domain interactor
SPATA2 spermatogenesis associated 2
SPHK1 sphingosine kinase 1
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SYK spleen tyrosine kinase
TMC8 transmembrane channel-like 8
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRAIP TRAF interacting protein
TRIM32 tripartite motif containing 32
UBE2K ubiquitin-conjugating enzyme E2K
ULK1 unc-51 like autophagy activating kinase 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF675 zinc finger protein 675