relapse Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The recurrence of a disease after treatment (Experimental Factor Ontology, EFO_0004952)
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Genes

301 genes co-occuring with the biological term relapse in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACKR3 atypical chemokine receptor 3
ACRBP acrosin binding protein
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALCAM activated leukocyte cell adhesion molecule
ALK anaplastic lymphoma receptor tyrosine kinase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
AQP4 aquaporin 4
AR androgen receptor
ATG16L2 autophagy related 16-like 2 (S. cerevisiae)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAALC brain and acute leukemia, cytoplasmic
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L12 BCL2-like 12 (proline rich)
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BSG basigin (Ok blood group)
C1QBP complement component 1, q subcomponent binding protein
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CALCA calcitonin-related polypeptide alpha
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCND1 cyclin D1
CD19 CD19 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD8A CD8a molecule
CD96 CD96 molecule
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CDX4 caudal type homeobox 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPA centromere protein A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
COMT catechol-O-methyltransferase
CREBBP CREB binding protein
CRHR1 corticotropin releasing hormone receptor 1
CRLF2 cytokine receptor-like factor 2
CRP C-reactive protein, pentraxin-related
CSMD1 CUB and Sushi multiple domains 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSD cathepsin D
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAOA D-amino acid oxidase activator
DIO2 deiodinase, iodothyronine, type II
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD2 dopamine receptor D2
EFNA1 ephrin-A1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EMP3 epithelial membrane protein 3
ENO2 enolase 2 (gamma, neuronal)
EPCAM epithelial cell adhesion molecule
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETV6 ets variant 6
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
FASLG Fas ligand (TNF superfamily, member 6)
FAT1 FAT atypical cadherin 1
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FHIT fragile histidine triad
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FOXM1 forkhead box M1
FOXP3 forkhead box P3
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GAS6 growth arrest-specific 6
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GDF15 growth differentiation factor 15
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLI1 GLI family zinc finger 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HPX hemopexin
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGH immunoglobulin heavy locus
IGHE immunoglobulin heavy constant epsilon
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL12A interleukin 12A
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
IRF4 interferon regulatory factor 4
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK2 Janus kinase 2
KDM1A lysine (K)-specific demethylase 1A
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK14 kallikrein-related peptidase 14
KLK3 kallikrein-related peptidase 3
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LCK LCK proto-oncogene, Src family tyrosine kinase
LDHA lactate dehydrogenase A
LEP leptin
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MCAM melanoma cell adhesion molecule
MCL1 myeloid cell leukemia 1
MDK midkine (neurite growth-promoting factor 2)
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MIR10A microRNA 10a
MIR10B microRNA 10b
MIR126 microRNA 126
MIR145 microRNA 145
MIR185 microRNA 185
MIR215 microRNA 215
MIR296 microRNA 296
MIR29C microRNA 29c
MIR30A microRNA 30a
MIR367 microRNA 367
MIR410 microRNA 410
MKI67 marker of proliferation Ki-67
MME membrane metallo-endopeptidase
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MOG myelin oligodendrocyte glycoprotein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCAM1 neural cell adhesion molecule 1
NCOR1 nuclear receptor corepressor 1
NEU3 sialidase 3 (membrane sialidase)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFRKB nuclear factor related to kappaB binding protein
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOVA1 neuro-oncological ventral antigen 1
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NT5C2 5'-nucleotidase, cytosolic II
NUCLEOLIN nucleolin multifunctional protein
NUP214 nucleoporin 214kDa
OPRK1 opioid receptor, kappa 1
P2RY8 purinergic receptor P2Y, G-protein coupled, 8
PDCD1LG2 programmed cell death 1 ligand 2
PDCD2 programmed cell death 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEBP1 phosphatidylethanolamine binding protein 1
PGR progesterone receptor
PI3 peptidase inhibitor 3, skin-derived
PICK1 protein interacting with PRKCA 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PML promyelocytic leukemia
PON1 paraoxonase 1
POU2AF1 POU class 2 associating factor 1
PRAME preferentially expressed antigen in melanoma
PRKCH protein kinase C, eta
PRKCZ protein kinase C, zeta
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP2 RAN binding protein 2
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
REG4 regenerating islet-derived family, member 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RFC1 replication factor C (activator 1) 1, 145kDa
RUNX1 runt-related transcription factor 1
S100A1 S100 calcium binding protein A1
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SDC1 syndecan 1
SELE selectin E
SELL selectin L
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD7 SMAD family member 7
SOCS3 suppressor of cytokine signaling 3
SOD2 superoxide dismutase 2, mitochondrial
SRRT serrate, RNA effector molecule
ST2 suppression of tumorigenicity 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
STC1 stanniocalcin 1
STK11 serine/threonine kinase 11
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYK spleen tyrosine kinase
SYNM synemin, intermediate filament protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TET2 tet methylcytosine dioxygenase 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TPMT thiopurine S-methyltransferase
TRAF2 TNF receptor-associated factor 2
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TYMS thymidylate synthetase
VCAN versican
VEGFA vascular endothelial growth factor A
WFDC2 WAP four-disulfide core domain 2
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
WWC1 WW and C2 domain containing 1
XPC xeroderma pigmentosum, complementation group C
YBX1 Y box binding protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZNF652 zinc finger protein 652